Pressure profile magnetic compression anastomosis devices
Compression anastomosis devices having a plurality of distinct pressure profile zones on the surface of the device. The anastomosis devices may be comprised of a plurality of magnetic connecting members arranged in an annular geometry, e.g., a polygon or circle. The anastomosis device may also be a continuous, non-segmented magnet, or other compression anastomosis device. The compression anastomosis device is deployed into a body lumen, e.g., endoscopically and/or laparoscopically, at a target site. A second compression anastomosis device is placed at an adjacent target site in an adjacent lumen. The compression anastomosis devices are brought together and mate, e.g., magnetically, creating an anastomosis.
1. A magnetic compression anastomosis device comprising:
at least one magnetic member that forms an annular shape including a tissue-engaging surface comprising a plurality of distinct pressure profile zones, where the plurality of distinct pressure profile zones comprises:
an inner cutting zone;
a fast release zone adjacent to the inner cutting zone;
a tissue fusion zone adjacent to the fast release zone; and
a relief zone adjacent to the tissue fusion zone.
2. A device according to claim 1 , wherein:
the relief zone is capable of generating pressure between around 0 psi to around 25 psi on body tissues;
the tissue fusion zone is capable of generating between around 25 psi to around 250 psi on body tissues;
the fast release zone is capable of generating between around 250 psi to around 40,000 psi on body tissues; and
the cutting zone is capable of generating between around 40,000 psi to around 75,000 psi on body tissues.
3. A device according to claim 1 , wherein the tissue-engaging surface comprises a knurled or cross-hatched geometric profile.
4. A device according to claim 1 , wherein a geometric profile of at least one of the distinct pressure profile zones is non-uniform and non-linear.
5. A device according to claim 1 , wherein the cutting zone comprises an angled cutting pressure profile.
6. A device according to claim 1 , wherein the annular shape is a polygon.
7. A device according to claim 1 , wherein the annular shape is a circle.
8. A device according to claim 1 , wherein the at least one magnetic member comprises a plurality of magnetic members that assemble into the annular shape.
9. A device according to claim 1 , wherein the at least one magnetic member is a unitary magnetic member forming the annular shape.
10. A system comprising:
a first magnetic compression anastomosis device comprising at least one magnetic member that forms an annular shape including a tissue-engaging surface comprising a plurality of distinct pressure profile zones, wherein the plurality of distinct pressure profile zones comprises an inner cutting zone, a fast release zone adjacent to the inner cutting zone, a tissue fusion zone adjacent to the fast release zone, and a relief zone adjacent to the tissue fusion zone; and
a second magnetic compression anastomosis device comprising at least one magnetic member that forms an annular shape including a tissue-engaging surface comprising a plurality of distinct pressure profile zones, wherein the plurality of distinct pressure profile zones comprises an inner cutting zone, a fast release zone adjacent to the inner cutting zone, a tissue fusion zone adjacent to the fast release zone, and a relief zone adjacent to the tissue fusion zone, the second magnetic compression anastomosis device and configured to engage with the first magnetic compression anastomosis device.
11. A system according to claim 10 , wherein:
the relief zone of each magnetic compression anastomosis device is capable of generating pressure between around 0 psi to around 25 psi on body tissues;
the tissue fusion zone of each magnetic compression anastomosis device is capable of generating between around 25 psi to around 250 psi on body tissues;
the fast release zone of each magnetic compression anastomosis device is capable of generating between around 250 psi to around 40,000 psi on body tissues; and
the cutting zone of each magnetic compression anastomosis device is capable of generating between around 40,000 psi to around 75,000 psi on body tissues.
12. A system according to claim 10 , wherein the tissue-engaging surface of at least one magnetic compression anastomosis device comprises a knurled or cross-hatched geometric profile.
13. A system according to claim 10 , wherein a geometric profile of at least one of the distinct pressure profile zones of each magnetic compression anastomosis device is non-uniform and non-linear.
14. A system according to claim 10 , wherein the cutting zone of each magnetic compression anastomosis device comprises an angled cutting pressure profile.
15. A system according to claim 10 , wherein the annular shape of each magnetic compression anastomosis device is a polygon.
16. A system according to claim 10 , wherein the annular shape of each magnetic compression anastomosis device is a circle.
17. A system according to claim 10 , wherein the at least one magnetic member of each magnetic compression anastomosis device comprises a plurality of magnetic members that assemble into the annular shape.
18. A system according to claim 10 , wherein the at least one magnetic member of each magnetic compression anastomosis device is a unitary magnetic member forming the annular shape.
19. A system according to claim 10 , wherein the first and second devices have the same pressure profile configurations.
20. A system according to claim 10 , wherein the first and second devices have different but complementary pressure profile configurations.