Pressure profile magnetic compression anastomosis devices
Compression anastomosis devices having a plurality of distinct pressure profile zones on the surface of the device. The anastomosis devices may be comprised of a plurality of magnetic connecting members arranged in an annular geometry, e.g., a polygon or circle. The anastomosis device may also be a continuous, non-segmented magnet, or other compression anastomosis device. The compression anastomosis device is deployed into a body lumen, e.g., endoscopically and/or laparoscopically, at a target site. A second compression anastomosis device is placed at an adjacent target site in an adjacent lumen. The compression anastomosis devices are brought together and mate, e.g., magnetically, creating an anastomosis.
1 . A magnetic compression anastomosis device comprising:
a plurality of magnetic connecting members configured to assemble into a magnetic compression anastomosis device having a tissue-engaging face composed of face portions of the plurality of magnetic connecting members, the tissue-engaging face including a plurality of distinct pressure profile zones selected from the group consisting of a cutting zone, a fast release zone, a tissue fusion zone, a relief zone, and a securing zone, wherein each distinct pressure profile zone is configured to generate pressure within a predetermined pressure range, and wherein the pressure ranges of the plurality of distinct pressure profile zones are configured to decrease radially outward from an inner diameter to an outer diameter of the magnetic compression anastomosis device.
2 . A device according to claim 1 , wherein the magnetic connecting members are configured to form an annular magnetic compression anastomosis device.
3 . A device according to claim 1 , wherein the magnetic connecting members are configured to self-assemble into the magnetic compression anastomosis device.
4 . A device according to claim 1 , wherein each of the magnetic connecting members includes a plurality of distinct pressure profile zones that collectively form the composite tissue-engaging face when the plurality of magnetic connecting members assemble into the magnetic compression anastomosis device.
5 . A device according to claim 1 , wherein:
the relief zone is capable of generating pressure between around 0 psi to around 25 psi on body tissues;
the tissue fusion zone is capable of generating between around 25 psi to around 250 psi on body tissues;
the fast release zone is capable of generating between around 250 psi to around 40,000 psi on body tissues; and
the cutting zone is capable of generating between around 40,000 psi to around 75,000 psi on body tissues.
6 . A device according to claim 1 , wherein at least one of:
the securing zone has a knurled or cross-hatched geometric profile; or
the cutting zone comprises an angled cutting pressure profile.
7 . A device according to claim 1 , wherein a geometric profile of at least one of the distinct pressure profile zones is non-uniform and non-linear.
8 . A device according to claim 1 , wherein the plurality of distinct pressure profile zones includes at least three distinct pressure profile zones.
9 . A device according to claim 2 , wherein the annular magnetic compression anastomosis device comprises a polygon or circle geometry.
10 . A system comprising:
a first magnetic compression anastomosis device according to claim 1 ; and
a second device configured to magnetically engage with the first magnetic compression anastomosis device.
11 . A system according to claim 10 , wherein the magnetic connecting members are configured to form an annular magnetic compression anastomosis device.
12 . A system according to claim 10 , wherein the magnetic connecting members are configured to self-assemble into the magnetic compression anastomosis device.
13 . A system according to claim 10 , wherein each of the magnetic connecting members includes a plurality of distinct pressure profile zones that collectively form the composite tissue-engaging face when the plurality of magnetic connecting members assemble into the magnetic compression anastomosis device.
14 . A system according to claim 10 , wherein:
the relief zone is capable of generating pressure between around 0 psi to around 25 psi on body tissues;
the tissue fusion zone is capable of generating between around 25 psi to around 250 psi on body tissues;
the fast release zone is capable of generating between around 250 psi to around 40,000 psi on body tissues; and
the cutting zone is capable of generating between around 40,000 psi to around 75,000 psi on body tissues.
15 . A system according to claim 10 , wherein at least one of:
the securing zone has a knurled or cross-hatched geometric profile; or
the cutting zone comprises an angled cutting pressure profile.
16 . A system according to claim 10 , wherein a geometric profile of at least one of the distinct pressure profile zones is non-uniform and non-linear.
17 . A system according to claim 10 , wherein the plurality of distinct pressure profile zones includes at least three distinct pressure profile zones.
18 . A system according to claim 11 , wherein the annular magnetic compression anastomosis device comprises a polygon or circle geometry.
19 . A system according to claim 10 , wherein the first and second devices have the same pressure profile configurations.
20 . A system according to claim 10 , wherein the first and second devices have different but complementary pressure profile configurations.