Granted Patent
B2
US 12,186,315 · App. 18/130,178 · Granted Jan 7, 2025
Cholesteryl ester transfer protein (CETP) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases
Inventors:
John Ford (Cambridgeshire, GB); Patrick Round (Suffolk, GB); John Kastelein (Amsterdam, NL); Atsuhiro Kawaguchi (Osaka, JP); Koichi Tomiyasu (Osaka, JP); Kozo Oka (Osaka, JP)
Assignee:
NewAmsterdam Pharma B.V.
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Abstract
The present invention relates to a cholesteryl ester transfer protein (CETP) inhibitor: (Compound A) for use in the treatment of subjects suffering from or having an increased risk for cardiovascular diseases, in particular hyperlipidemia or mixed dyslipidemia. A further aspect of the present invention relates to a pharmaceutical composition for use in the treatment of subjects suffering from or having an increased risk for cardiovascular diseases, wherein the composition comprises a therapeutically effective amount of said Compound A CETP inhibitor.
Claims (5)
1. An oral daily dosage form comprising 1 to 25 mg of the compound:
(hereinafter: Compound A) or a pharmaceutically acceptable salt thereof.
2. The oral daily dosage form according to claim 1 , wherein the dosage form is a tablet.
3. The oral daily dosage form according to claim 2 , wherein the tablet comprises 10 mg of Compound A or the pharmaceutically acceptable salt thereof.
4. The oral daily dosage form according to claim 2 , wherein the tablet comprises 5 mg of Compound A or the pharmaceutically acceptable salt thereof.
Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 22, 2024
From: DEZIMA PHARMA B.V.
To: NEWAMSTERDAM PHARMA B.V.
Reel/Frame 066646/0337 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 22, 2024
From: KAWAGUCHI, ATSUHIRO; TOMIYASU, KOUICHI; OKA, KOUZOU
To: MITSUBISHI TANABE PHARMA CORPORATION
Reel/Frame 066528/0300 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 22, 2024
From: MITSUBISHI TANABE PHARMA CORPORATION
To: DEZIMA PHARMA B.V.
Reel/Frame 066528/0407 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 3, 2023
From: FORD, JOHN; ROUND, PATRICK; KASTELEIN, JOHN
To: DEZIMA PHARMA B.V.
Reel/Frame 063207/0010 →
Continuity (4)
Division
15117154
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