IP Library › Granted Patent US 12,186,535
Granted Patent B2
US 12,186,535 · App. 18/213,555 · Granted Jan 7, 2025

System and method for an injection using a syringe needle

Inventors: John B. Slate (Encinitas, CA); Richard J. Koerner (San Diego, CA); Corey M. Magers (Oceanside, CA); Michael W. Burk (San Marcos, CA)
Assignee: AVANT MEDICAL CORP.
A61M5/20A61M5/326A61M2005/206A61M2005/208A61M2005/31588A61M2205/50A61M2205/6045
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Quick Facts
Patent No.
US 12,186,535
App. No.
18/213,555
Granted
Jan 7, 2025
Kind
B2
Abstract

An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection.

Claims (31)

1. A system for injecting a fluid medicament into a patient which comprises:

a cassette having: a housing; a latch mechanism; and a hypodermic syringe, wherein the latch mechanism is operable to selectively hold the hypodermic syringe in the housing;

an injector configured to be selectively coupled with the cassette such that the cassette is removably received in the injector;

a first motor mounted on the injector, the first motor being engageable with the cassette for moving the hypodermic syringe relative to the housing between a first position and a second position;

a second motor mounted on the injector, the second motor being engageable with the hypodermic syringe for expelling the fluid medicament from the hypodermic syringe; and

a computer mounted on the injector for coordinated control of the first and second motors.

2. The system as recited in claim 1 , wherein the hypodermic syringe comprises:

a syringe chamber for holding the fluid medicament therein;

an injection needle extending from the syringe chamber; and

a plunger slidably mounted for advancement into the syringe chamber to expel the fluid medicament therefrom through the injection needle.

3. The system as recited in claim 2 , wherein the first position is characterized by the injection needle being withdrawn and concealed within the housing, and the second position is characterized by having the injection needle extend from the housing and from the injector for expelling the fluid medicament from the hypodermic syringe.

4. The system as recited in claim 3 , wherein the latch mechanism is operable to fixedly hold the hypodermic syringe in the first position.

5. The system as recited in claim 4 , wherein a duty cycle requires, in sequence:

computer control of the first motor for movement of the hypodermic syringe at a predetermined speed from the first position to the second position;

computer control of the second motor for advancement of the plunger into the syringe chamber at a predetermined rate for expelling fluid medicament from the hypodermic syringe; and

computer control of the first motor for withdrawal of the hypodermic syringe from the second position to the first position and for activation of the latch mechanism to fixedly hold the hypodermic syringe in the first position.

6. The system as recited in claim 5 , wherein the predetermined speed for advancement of the hypodermic syringe from the first position to the second position is approximately 0.1 to 1 m/s.

7. The system as recited in claim 3 , wherein the housing is formed with an orifice to allow for extension of the injection needle from the housing, and the system further comprises a skin sensor mounted on the injector adjacent the orifice to generate a contact signal whenever the orifice is positioned against the skin of the patient.

8. The system as recited in claim 1 , wherein the cassette further comprises: a sleeve slidingly coupled to the housing such that the sleeve is selectively movable between the first position and the second position, wherein the hypodermic syringe is fixedly held on the sleeve for movement therewith, and the latch mechanism includes a first part formed on the housing and a second part formed on the sleeve.

9. A system for injecting a fluid medicament into a patient which comprises:

a hypodermic syringe having a syringe chamber for holding the fluid medicament therein, an injection needle extending from the syringe chamber, and a plunger slidably mounted for advancement into the syringe chamber to expel fluid medicament therefrom through the injection needle;

a cassette for holding the hypodermic syringe, the cassette being operable such that the hypodermic syringe is selectively moveable between a first position wherein the injection needle is withdrawn and concealed and a second position wherein the injection needle extends from the cassette for expelling the fluid medicament from the hypodermic syringe; and

an injector configured to be selectively coupled with the cassette such that the cassette is removably received in the injector, the injector comprising a drive means configured to be engaged with the cassette and the hypodermic syringe, the drive means being bifurcated to have a first motor for moving the hypodermic syringe between the first and second positions and a second motor for advancing the plunger into the syringe chamber to expel the fluid medicament when the hypodermic syringe is in the second position.

10. The system as recited in claim 9 , wherein the cassette includes:

a housing; and

a latch mechanism comprising a portion of the housing operable to hold the hypodermic syringe in the first position.

11. The system as recited in claim 10 , wherein the cassette further comprises a sleeve slidingly coupled to the housing such that the sleeve is movable between the first position and the second position, wherein the hypodermic syringe is fixedly held on the sleeve for movement therewith, and the latch mechanism comprises the portion of the housing and a portion of the sleeve.

12. The system as recited in claim 10 , wherein the first motor is engageable with the housing for moving the hypodermic syringe between the first and second positions.

13. The system as recited in claim 10 , further comprising a computer coupled to the drive means for coordinated control of the first motor and the second motor.

14. The system as recited in claim 13 , wherein a duty cycle requires, in sequence: computer control of the first motor for movement of the hypodermic syringe at a predetermined speed from the first position to the second position; computer control of the second motor for advancement of the plunger into the syringe chamber with a predetermined force at a predetermined rate for expelling fluid medicament from the hypodermic syringe; and computer control of the first motor for withdrawal of the hypodermic syringe from the first position to the second position and for activation of the latch mechanism to fixedly hold the hypodermic syringe in the first position.

15. The system as recited in claim 14 , wherein the predetermined speed for advancement of the hypodermic syringe from the first position to the second position is approximately 0.1 to 1 m/s.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2023
From: SLATE, JOHN B., MR.; KOERNER, RICHARD J., MR.; MAGERS, COREY M., MR.; BURK, MICHAEL W., MR.
To: AVANT MEDICAL CORP.
Reel/Frame 064509/0886 →
Continuity (5)
Continuation 16832987 · Mar 27, 2020
Division 15440420 · Feb 23, 2017
Division 13269750 · Oct 10, 2011
Continuation 12178447 · Jul 23, 2008
Related Publication 20230330338A1 · Oct 19, 2023
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