IP Library › Granted Patent US 12,226,233
Granted Patent B2
US 12,226,233 · App. 18/538,581 · Granted Feb 18, 2025

Personalized breast imaging system

Inventors: Biao Chen (Newark, DE); Haili Chui (Fremont, CA)
Assignee: Hologic, Inc.
A61B5/708A61B5/004A61B5/0073A61B5/0077A61B5/1072A61B5/4312A61B5/442A61B17/3403G06N20/00G06T5/50G06T2207/20221
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Quick Facts
Patent No.
US 12,226,233
App. No.
18/538,581
Filed
Dec 13, 2023
Granted
Feb 18, 2025
Kind
B2
Art Unit
2884
USPC
378/20
Abstract

Examples of the present disclosure describe systems and methods for personalized breast imaging. In aspects, a first set of patient attributes may be collected. The first set of patient attributes may relate to, or be used to determine, for example, breast size, breast thickness, and/or three-dimensional (3D) breast shape. The first set of patient attributes may be used to customize image acquisition parameters for the patient. A second set of patient attributes may also be collected. The second set of patient attributes may relate to, or be used to determine, for example, breast elasticity and breast density. The second set of patient attributes may be used to customize breast compression parameters for the patient. The customized image acquisition parameters and breast compression parameters may then be used to perform one or more procedures (e.g., an imaging procedure, a biopsy procedure, etc.) on the patient's breast.

Claims (46)

1. An imaging system for imaging a breast of a patient, the imaging system comprising:

an x-ray imaging device including an x-ray tube and an x-ray detector;

a breast compression device including a paddle and a platform;

at least one processor; and

memory coupled to the at least one processor, the memory comprising computer executable instructions that, when executed by the at least one processor, performs a set of operations comprising:

receiving a first set of physical attributes for the breast of the patient, wherein the first set of physical attributes are specific to the patient and comprise at least one of breast size, breast thickness, breast shape, breast volume data, and breast surface points;

customizing image acquisition parameters for the x-ray imaging device specific for the breast of the patient based on the first set of physical attributes, wherein the image acquisition parameters include automatic exposure control function, a spatial thickness distribution of tissue, and a desired number range of image slices used for breast volume reconstruction, the number of slices being based on breast thickness;

receiving a second set of physical attributes for the breast of the patient, wherein the second set of physical attributes comprise at least one of breast elasticity, breast composition distributions, and breast density; and

customizing compression parameters for the breast compression device specific for the breast of the patient based on at least one of the first set of physical attributes and the second set of physical attributes;

wherein the breast compression device is configured to compress the breast of the patient based on the customized compression parameters for the breast of the patient and the x-ray imaging device is configured to image the breast of the patient based on the customized image acquisition parameters for the breast of the patient, and

wherein the memory is configured to store the first set of physical attributes for the breast of the patient, the customized image acquisition parameters for the breast of the patient, the second set of physical attributes for the breast of the patient, and the customized compression parameters for the breast of the patient.

2. The imaging system of claim 1 , wherein the customized compression parameters for the breast compression device are only based on the second set of physical attributes.

3. The imaging system of claim 1 , wherein the first set of physical attributes include breast size.

4. The imaging system of claim 3 , wherein the set of operations further includes collecting one or more images for determination of breast size.

5. The imaging system of claim 4 , further comprising at least one imaging device used to collect the one or more images.

6. The imaging system of claim 1 , wherein the set of operations further includes collecting one or more images for generating at least some of the first set of physical attributes.

7. The imaging system of claim 6 , further comprising a stereo depth sensor, an HD camera, a tracking sensor, a computer vision algorithm, or a machine learning algorithm used to collect the one or more images.

8. The imaging system of claim 1 , wherein the set of operations further includes:

applying, to the at least one of the first set of physical attributes and the second set of physical attributes for the breast of the patient, a compression algorithm for determining breast compression force; and

receiving, as output from the compression algorithm, an optimal compression force for the breast of the patient.

9. The imaging system of claim 8 , wherein the optimal compression force for the breast of the patient represents a minimum compression force required to stabilize the breast of the patient and acquire a desired image quality.

10. The imaging system of claim 1 , wherein the set of operations further includes:

imaging the breast of the patient using the customized image acquisition parameters; and

receiving as output from the imaging, one or more breast images.

11. The imaging system of claim 1 , a wherein the paddle has one or more compression force sensors.

12. A method for imaging a breast of a patient, the method comprising:

receiving a first set of physical attributes for the breast of the patient at an imaging system, wherein the first set of physical attributes are specific to the patient and comprise at least one of breast size, breast thickness, breast shape, breast volume data, and breast surface points;

customizing image acquisition parameters for an x-ray imaging device of the imaging system specific for the breast of the patient based on the first set of physical attributes, wherein the image acquisition parameters include automatic exposure control function, a spatial thickness distribution of tissue, and a desired number range of image slices used for breast volume reconstruction, the number of slices being based on breast thickness;

receiving a second set of physical attributes for the breast of the patient at the imaging system, wherein the second set of physical attributes comprise at least one of breast elasticity, breast composition distributions, and breast density;

customizing compression parameters for a breast compression device of the imaging device specific for the breast of the patient based on at least one of the first set of physical attributes and the second set of physical attributes;

compressing the breast of the patient at the breast compression device based on the customized compression parameters for the breast of the patient;

imaging the breast of the patient via the x-ray imaging device based on the customized image acquisition parameters for the breast of the patient; and

storing the first set of physical attributes for the breast of the patient, the customized image acquisition parameters for the breast of the patient, the second set of physical attributes for the breast of the patient, and the customized compression parameters for the breast of the patient.

13. The method of claim 12 , wherein the customized compression parameters for the breast compression device are only based on the second set of physical attributes.

14. The method of claim 12 , wherein the first set of physical attributes include breast size.

15. The method of claim 14 , further comprising collecting one or more images for determination of breast size.

16. The method of claim 12 , further comprising collecting one or more images for generating at least some of the first set of physical attributes.

17. The method of claim 12 , further comprising:

applying, to the at least one of the first set of physical attributes and the second set of physical attributes for the breast of the patient, a compression algorithm for determining breast compression force; and

receiving, as output from the compression algorithm, an optimal compression force for the breast of the patient.

18. The method of claim 17 , wherein the optimal compression force for the breast of the patient represents a minimum compression force required to stabilize the breast of the patient and acquire a desired image quality.

19. The method of claim 12 , further comprising

generating, during the imaging of the compressed breast, one or more breast images;

registering breast tissue identified in the one or more breast images; and

fusing the registered breast tissue to create one or more fused breast images.

20. The method of claim 12 , further comprising monitoring patient movement in real-time.

Assignments (5)
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 069172/0436 Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC.; GEN-PROBE INCORPORATED; FAXITRON BIOPTICS, LLC
Reel/Frame 075503/0086 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 075926/0339 →
SECURITY INTEREST Recorded Oct 14, 2024
From: HOLOGIC, INC.; GEN-PROBE INCORPORATED; FAXITRON BIOPTICS, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 069172/0436 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2024
From: CHEN, BIAO; CHUI, HAILI
To: HOLOGIC, INC.
Reel/Frame 066081/0418 →
Continuity (3)
Continuation 16942268 · Jul 29, 2020
Provisional Application 62879758 · Jul 29, 2019
Related Publication 20240164720A1 · May 23, 2024
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