Granted Patent
B2
US 12,232,961 · App. 17/865,712 · Granted Feb 25, 2025
Mitral valve spacer device
Inventors:
Michael D. Franklin (Irvine, CA); Matthew T. Winston (Aliso Viejo, CA); Lauren R. Freschauf (Mission Viejo, CA); Eric Robert Dixon (Villa Park, CA); Yoon Hee Kwon (Mission Viejo, CA)
Assignee:
EDWARDS LIFESCIENCES CORPORATION
A61F2/246A61F2/2463A61F2/2409A61F2/2412A61F2/2436A61F2/2445A61F2/2457A61F2/2466A61F2210/0014A61F2220/0008A61F2220/0016A61F2250/0003A61F2250/0036A61F2250/0069
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Abstract
An implantable device includes an adjustable spacer and at least one anchor. The adjustable spacer is configured to be positioned between native heart valve leaflets to reduce regurgitation therebetween. The adjustable spacer can comprise a first side and a second side opposite the first side. Each side can be adjustable between a first width and a second width. Each side can be independently moved between the first width and the second width. The adjustable spacer can be made from a sponge material.
Claims (15)
1. A method for improving coaptation of native heart valve leaflets comprising:
advancing a delivery apparatus and an implantable prosthetic device into a body of a patient, the implantable prosthetic device comprising an adjustable spacer;
positioning the adjustable spacer between the native heart valve leaflets such that the adjustable spacer is offset from an area of regurgitation;
adjusting a size of the adjustable spacer while the adjustable spacer is disposed between the native heart valve leaflets so that the adjustable spacer assumes an asymmetric configuration such that the adjustable spacer blocks the area of regurgitation;
wherein the adjustable spacer has a first side adjustable in size and a second side adjustable in size; and
wherein the first side is adjusted in size independently of the second side.
2. The method of claim 1 , wherein the asymmetric configuration is asymmetric with respect to a central longitudinal axis of the adjustable spacer that extends from an upstream end to a downstream end of the adjustable spacer.
3. The method of claim 1 , wherein the asymmetric configuration is asymmetric with respect to a lateral axis of the adjustable spacer.
4. The method of claim 1 , wherein the first side and the second side are different sizes or shapes in an expanded configuration.
5. The method of claim 1 , wherein the size of the adjustable spacer is adjusted by inflating the adjustable spacer with an inflation medium.
6. A method for improving coaptation of native heart valve leaflets comprising:
advancing a delivery apparatus and an implantable prosthetic device into a body of a patient, the implantable prosthetic device comprising an adjustable spacer;
positioning the adjustable spacer between the native heart valve leaflets such that the adjustable spacer is offset from an area of regurgitation;
wherein the adjustable spacer is offset toward an A1/P1 location when the area of regurgitation is an A2/P2 location; and
adjusting a size of the adjustable spacer while the adjustable spacer is disposed between the native heart valve leaflets so that the adjustable spacer assumes an asymmetric configuration such that the adjustable spacer blocks the area of regurgitation.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 20, 2025
From: FRANKLIN, MICHAEL D.; WINSTON, MATTHEW T.; FRESCHAUF, LAUREN R.; DIXON, ERIC ROBERT; KWON, YOON HEE
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 069932/0024 →
Continuity (3)
Provisional Application
62656533
· Apr 12, 2018
References Cited (400)
US 3874388A
· King et al.
· 1975
[cited by applicant]
US 4340091A
· Skelton et al.
· 1982
[cited by applicant]
US 4506669A
· Blake, III
· 1985
[cited by applicant]
US 4590937A
· Deniega
· 1986
[cited by applicant]
US 4693248A
· Failla
· 1987
[cited by applicant]
US 4803983A
· Siegel
· 1989
[cited by applicant]
US 5125895A
· Buchbinder et al.
· 1992
[cited by applicant]
US 5171252A
· Friedland
· 1992
[cited by applicant]
US 5195962A
· Martin et al.
· 1993
[cited by applicant]
US 5292326A
· Green et al.
· 1994
[cited by applicant]
US 5327905A
· Avitall
· 1994
[cited by applicant]
US 5363861A
· Edwards et al.
· 1994
[cited by applicant]
US 5370685A
· Stevens
· 1994
[cited by applicant]
US 5389077A
· Melinyshyn et al.
· 1995
[cited by applicant]
US 5411552A
· Andersen et al.
· 1995
[cited by applicant]
US 5450860A
· O'Connor
· 1995
[cited by applicant]
US 5456674A
· Bos et al.
· 1995
[cited by applicant]
US 5474057A
· Makower et al.
· 1995
[cited by applicant]
US 5478353A
· Yoon
· 1995
[cited by applicant]
US 5487746A
· Yu et al.
· 1996
[cited by applicant]
US 5565004A
· Christoudias
· 1996
[cited by applicant]
US 5607462A
· Imran
· 1997
[cited by applicant]
US 5609598A
· Laufer et al.
· 1997
[cited by applicant]
US 5611794A
· Sauer et al.
· 1997
[cited by applicant]
US 5626607A
· Malecki et al.
· 1997
[cited by applicant]
US 5695504A
· Gifford, III et al.
· 1997
[cited by applicant]
US 5716417A
· Girard et al.
· 1998
[cited by applicant]
US 5727569A
· Benetti et al.
· 1998
[cited by applicant]
US 5741297A
· Simon
· 1998
[cited by applicant]
US 5782746A
· Wright
· 1998
[cited by applicant]
US 5797960A
· Stevens et al.
· 1998
[cited by applicant]
US 5836311A
· Borst et al.
· 1998
[cited by applicant]
US 5843076A
· Webster, Jr. et al.
· 1998
[cited by applicant]
US 5855590A
· Malecki et al.
· 1999
[cited by applicant]
US 5885271A
· Hamilton et al.
· 1999
[cited by applicant]
US 5888247A
· Benetti
· 1999
[cited by applicant]
US 5891017A
· Swindle et al.
· 1999
[cited by applicant]
US 5891112A
· Samson
· 1999
[cited by applicant]
US 5894843A
· Benetti et al.
· 1999
[cited by applicant]
US 5921979A
· Kovac et al.
· 1999
[cited by applicant]
US 5944738A
· Amplatz et al.
· 1999
[cited by applicant]
US 5957835A
· Anderson et al.
· 1999
[cited by applicant]
US 5972020A
· Carpentier et al.
· 1999
[cited by applicant]
US 5980534A
· Gimpelson
· 1999
[cited by applicant]
US 6004329A
· Myers et al.
· 1999
[cited by applicant]
US 6010531A
· Donlon et al.
· 2000
[cited by applicant]
US 6017358A
· Yoon et al.
· 2000
[cited by applicant]
US 6086600A
· Kortenbach
· 2000
[cited by applicant]
US 6120496A
· Whayne et al.
· 2000
[cited by applicant]
US 6132370A
· Furnish et al.
· 2000
[cited by applicant]
US 6162239A
· Manhes
· 2000
[cited by applicant]
US 6165183A
· Kuehn et al.
· 2000
[cited by applicant]
US 6182664B1
· Cosgrove
· 2001
[cited by applicant]
US 6193732B1
· Frantzen et al.
· 2001
[cited by applicant]
US 6193734B1
· Bolduc et al.
· 2001
[cited by applicant]
US 6200315B1
· Gaiser et al.
· 2001
[cited by applicant]
US 6228032B1
· Eaton et al.
· 2001
[cited by applicant]
US 6241743B1
· Levin et al.
· 2001
[cited by applicant]
US 6269819B1
· Oz et al.
· 2001
[cited by applicant]
US 6269829B1
· Chen et al.
· 2001
[cited by applicant]
US 6312447B1
· Grimes
· 2001
[cited by applicant]
US 6461366B1
· Seguin
· 2002
[cited by applicant]
US 6468285B1
· Hsu et al.
· 2002
[cited by applicant]
US 6508806B1
· Hoste
· 2003
[cited by applicant]
US 6508825B1
· Selmon et al.
· 2003
[cited by applicant]
US 6530933B1
· Yeung et al.
· 2003
[cited by applicant]
US 6537290B2
· Adams et al.
· 2003
[cited by applicant]
US 6544215B1
· Bencini et al.
· 2003
[cited by applicant]
US 6626930B1
· Allen et al.
· 2003
[cited by applicant]
US 6629534B1
· St. Goar et al.
· 2003
[cited by applicant]
US 6719767B1
· Kimblad
· 2004
[cited by applicant]
US 6764510B2
· Vidlund et al.
· 2004
[cited by applicant]
US 6770083B2
· Seguin
· 2004
[cited by applicant]
US 6837867B2
· Kortelling
· 2005
[cited by applicant]
US 6855137B2
· Bon
· 2005
[cited by applicant]
US 6913614B2
· Marino et al.
· 2005
[cited by applicant]
US 6939337B2
· Parker et al.
· 2005
[cited by applicant]
US 6945956B2
· Waldhauser et al.
· 2005
[cited by applicant]
US 7048754B2
· Martin et al.
· 2006
[cited by applicant]
US 7101395B2
· Tremulis et al.
· 2006
[cited by applicant]
US 7125421B2
· Tremulis et al.
· 2006
[cited by applicant]
US 7288097B2
· Seguin
· 2007
[cited by applicant]
US 7371210B2
· Brock et al.
· 2008
[cited by applicant]
US 7464712B2
· Oz et al.
· 2008
[cited by applicant]
US 7509959B2
· Oz et al.
· 2009
[cited by applicant]
US 7569062B1
· Kuehn et al.
· 2009
[cited by applicant]
US 7682369B2
· Seguin
· 2010
[cited by applicant]
US 7731706B2
· Potter
· 2010
[cited by applicant]
US 7744609B2
· Allen et al.
· 2010
[cited by applicant]
US 7748389B2
· Salahieh et al.
· 2010
[cited by applicant]
US 7753932B2
· Gingrich et al.
· 2010
[cited by applicant]
US 7758596B2
· Oz et al.
· 2010
[cited by applicant]
US 7780723B2
· Taylor
· 2010
[cited by applicant]
US 7803185B2
· Gabbay
· 2010
[cited by applicant]
US 7824443B2
· Salahieh et al.
· 2010
[cited by applicant]
US 7981123B2
· Seguin
· 2011
[cited by applicant]
US 7988724B2
· Salahieh et al.
· 2011
[cited by applicant]
US 8052750B2
· Tuval et al.
· 2011
[cited by applicant]
US 8070805B2
· Vidlund et al.
· 2011
[cited by applicant]
US 8096985B2
· Legaspi et al.
· 2012
[cited by applicant]
US 8104149B1
· McGarity
· 2012
[cited by applicant]
US 8133239B2
· Oz et al.
· 2012
[cited by applicant]
US 8147542B2
· Maisano et al.
· 2012
[cited by applicant]
US 8172856B2
· Eigler et al.
· 2012
[cited by applicant]
US 8206437B2
· Bonhoeffer et al.
· 2012
[cited by applicant]
US 8216301B2
· Bonhoeffer et al.
· 2012
[cited by applicant]
US 8303653B2
· Bonhoeffer et al.
· 2012
[cited by applicant]
US 8313525B2
· Tuval et al.
· 2012
[cited by applicant]
US 8348995B2
· Tuval et al.
· 2013
[cited by applicant]
US 8348996B2
· Tuval et al.
· 2013
[cited by applicant]
US 8414643B2
· Tuval et al.
· 2013
[cited by applicant]
US 8425404B2
· Wilson et al.
· 2013
[cited by applicant]
US 8449599B2
· Chau et al.
· 2013
[cited by applicant]
US 8449606B2
· Eliasen et al.
· 2013
[cited by applicant]
US 8460368B2
· Taylor et al.
· 2013
[cited by applicant]
US 8470028B2
· Thornton et al.
· 2013
[cited by applicant]
US 8480730B2
· Maurer et al.
· 2013
[cited by applicant]
US 8540767B2
· Zhang
· 2013
[cited by applicant]
US 8579965B2
· Bonhoeffer et al.
· 2013
[cited by applicant]
US 8585756B2
· Bonhoeffer et al.
· 2013
[cited by applicant]
US 8652202B2
· Alon et al.
· 2014
[cited by applicant]
US 8668733B2
· Haug et al.
· 2014
[cited by applicant]
US 8721665B2
· Oz et al.
· 2014
[cited by applicant]
US 8740918B2
· Seguin
· 2014
[cited by applicant]
US 8771347B2
· DeBoer et al.
· 2014
[cited by applicant]
US 8778017B2
· Eliasen et al.
· 2014
[cited by applicant]
US 8834564B2
· Tuval et al.
· 2014
[cited by applicant]
US 8840663B2
· Salahieh et al.
· 2014
[cited by applicant]
US 8876894B2
· Tuval et al.
· 2014
[cited by applicant]
US 8876895B2
· Tuval et al.
· 2014
[cited by applicant]
US 8945177B2
· Dell et al.
· 2015
[cited by applicant]
US 9034032B2
· McLean et al.
· 2015
[cited by applicant]
US 9198757B2
· Schroeder et al.
· 2015
[cited by applicant]
US 9220507B1
· Patel et al.
· 2015
[cited by applicant]
US 9259317B2
· Wilson et al.
· 2016
[cited by applicant]
US 9282972B1
· Patel et al.
· 2016
[cited by applicant]
US 9301834B2
· Tuval et al.
· 2016
[cited by applicant]
US 9308360B2
· Bishop et al.
· 2016
[cited by applicant]
US 9387071B2
· Tuval et al.
· 2016
[cited by applicant]
US 9427327B2
· Parrish
· 2016
[cited by applicant]
US 9439763B2
· Geist et al.
· 2016
[cited by applicant]
US 9510837B2
· Seguin
· 2016
[cited by applicant]
US 9510946B2
· Chau et al.
· 2016
[cited by applicant]
US 9572660B2
· Braido et al.
· 2017
[cited by applicant]
US 9642704B2
· Tuval et al.
· 2017
[cited by applicant]
US 9700445B2
· Martin et al.
· 2017
[cited by applicant]
US 9775963B2
· Miller
· 2017
[cited by applicant]
US D809139S
· Marsot et al.
· 2018
[cited by applicant]
US 9889002B2
· Bonhoeffer et al.
· 2018
[cited by applicant]
US 9949824B2
· Bonhoeffer et al.
· 2018
[cited by applicant]
US 20010005787A1
· Oz et al.
· 2001
[cited by applicant]
US 20020013571A1
· Goldfarb et al.
· 2002
[cited by applicant]
US 20020107531A1
· Schreck et al.
· 2002
[cited by applicant]
US 20020173811A1
· Tu et al.
· 2002
[cited by applicant]
US 20030144573A1
· Heilman et al.
· 2003
[cited by applicant]
US 20030208231A1
· Williamson et al.
· 2003
[cited by applicant]
US 20040034365A1
· Lentz et al.
· 2004
[cited by applicant]
US 20040044350A1
· Martin et al.
· 2004
[cited by applicant]
US 20040127982A1
· Machold et al.
· 2004
[cited by applicant]
US 20040220593A1
· Greenhalgh
· 2004
[cited by applicant]
US 20050165429A1
· Douglas et al.
· 2005
[cited by applicant]
US 20050216039A1
· Lederman
· 2005
[cited by applicant]
US 20060100649A1
· Hart
· 2006
[cited by applicant]
US 20060178700A1
· Quinn
· 2006
[cited by applicant]
US 20070010877A1
· Salahieh et al.
· 2007
[cited by applicant]
US 20070093857A1
· Rogers et al.
· 2007
[cited by applicant]
US 20070156197A1
· Root et al.
· 2007
[cited by applicant]
US 20070191154A1
· Genereux et al.
· 2007
[cited by applicant]
US 20070198038A1
· Cohen et al.
· 2007
[cited by applicant]
US 20070293943A1
· Quinn
· 2007
[cited by applicant]
US 20070299424A1
· Cumming et al.
· 2007
[cited by applicant]
US 20080039743A1
· Fox et al.
· 2008
[cited by applicant]
US 20080091169A1
· Heideman et al.
· 2008
[cited by applicant]
US 20080294247A1
· Yang et al.
· 2008
[cited by applicant]
US 20090177266A1
· Powell et al.
· 2009
[cited by applicant]
US 20090287304A1
· Dahlgren et al.
· 2009
[cited by applicant]
US 20100249497A1
· Peine et al.
· 2010
[cited by applicant]
US 20100298929A1
· Thornton et al.
· 2010
[cited by applicant]
US 20110082538A1
· Dahlgren et al.
· 2011
[cited by applicant]
US 20110257723A1
· McNamara
· 2011
[cited by applicant]
US 20130041314A1
· Dillon
· 2013
[cited by applicant]
US 20130073034A1
· Wilson et al.
· 2013
[cited by applicant]
US 20130190861A1
· Chau et al.
· 2013
[cited by applicant]
US 20130282059A1
· Ketai et al.
· 2013
[cited by applicant]
US 20130304197A1
· Buchbinder et al.
· 2013
[cited by applicant]
US 20140031928A1
· Murphy et al.
· 2014
[cited by applicant]
US 20140067048A1
· Chau et al.
· 2014
[cited by applicant]
US 20140200662A1
· Eftel et al.
· 2014
[cited by applicant]
US 20140277427A1
· Ratz et al.
· 2014
[cited by applicant]
US 20140324164A1
· Gross et al.
· 2014
[cited by applicant]
US 20150094802A1
· Buchbinder et al.
· 2015
[cited by applicant]
US 20150100116A1
· Mohl et al.
· 2015
[cited by applicant]
US 20150157268A1
· Winshtein et al.
· 2015
[cited by applicant]
US 20150223793A1
· Goldfarb et al.
· 2015
[cited by applicant]
US 20150257757A1
· Powers et al.
· 2015
[cited by applicant]
US 20150313592A1
· Coillard-Lavirotte et al.
· 2015
[cited by applicant]
US 20160106539A1
· Buchbinder et al.
· 2016
[cited by applicant]
US 20160354082A1
· Oz et al.
· 2016
[cited by applicant]
US 20170042456A1
· Budiman
· 2017
[cited by applicant]
US 20170049455A1
· Seguin
· 2017
[cited by applicant]
US 20170239048A1
· Goldfarb et al.
· 2017
[cited by applicant]
US 20170325949A1
· Rodgers
· 2017
[cited by examiner]