Granted Patent
B2
US 12,245,935 · App. 17/094,205 · Granted Mar 11, 2025
Composite web-polymer heart valve
Assignee:
Boston Scientific Limited
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Abstract
Embodiments herein relate to polymer coated prosthetic heart valves. In an embodiment, a method of manufacturing a heart valve is included, the method obtaining a frame, attaching a porous web to the frame, applying a coating over at least a portion of the porous web. In an embodiment a heart valve is included. The heart valve including a frame and a plurality of valve leaflets attached to the frame. Each valve leaflet can have a first polymer forming a porous support web and a second polymer forming a coating occluding pores in the porous support web. The valve leaflets can be attached to the frame with a connection structure that is at least partially covered by the coating. Other embodiments are also included herein.
Claims (29)
1. A method of manufacturing a heart valve comprising:
obtaining a frame;
attaching a porous web to the frame with a plurality of attachment elements;
applying a coating over at least a portion of the porous web, which is attached to the frame, and at least a portion of the plurality of attachment elements, which attach the porous web to the frame, to form an inner skirt and a plurality of leaflets;
wherein the attachment elements do not pass through the coating on the porous web.
2. The method of claim 1 , wherein the porous web comprises a mesh.
3. The method of claim 1 , wherein attaching the porous web to the frame comprises suturing the porous web to the frame.
4. The method of claim 3 , wherein the plurality of attachment elements comprises a plurality of sutures.
5. The method of claim 1 , wherein applying the coating over the porous web occludes pores within the porous web.
6. The method of claim 1 , wherein the porous web defines at least one valve leaflet.
7. The method of claim 1 , wherein the porous web comprises an electrospun substrate.
8. The method of claim 7 , wherein the electrospun substrate corresponds to at least one valve leaflet.
9. The method of claim 7 , wherein the electrospun substrate comprises a polyisobutylene urethane (PIB-PUR) copolymer and the porous web comprises polyethylene terephthalate.
10. The method of claim 1 , wherein the coating is applied to the frame and the attachment elements at the same time.
11. The method of claim 1 , wherein the coating occludes the pores in the porous web such that fluids are unable to pass through the coated porous web.
12. The method of claim 1 , wherein the entire porous web and frame are covered in the coating.
13. A method of manufacturing a heart valve comprising:
obtaining a frame;
attaching a porous web to the frame with a plurality of attachment elements; and
applying a coating over at least a portion of the porous web, which is attached to the frame, and at least a portion of the plurality of attachment elements, which attach the porous web to the frame, to form an inner skirt and a plurality of leaflets;
wherein the coating is applied to the frame and the attachment elements at the same time.
14. The method of claim 13 , wherein attaching the porous web to the frame comprises suturing the porous web to the frame.
15. The method of claim 14 , wherein the plurality of attachment elements comprises a plurality of sutures.
16. The method of claim 13 , wherein applying a coating over the porous web occludes pores within the porous web.
17. A method of manufacturing a heart valve comprising:
obtaining a frame;
attaching a porous web to the frame with a plurality of attachment elements; and
applying a coating over at least a portion of the porous web, which is attached to the frame, and at least a portion of the plurality of attachment elements, which attach the porous web to the frame, to form an inner skirt and a plurality of leaflets;
wherein the porous web comprises an electrospun substrate, wherein the electrospun substrate comprises a polyisobutylene urethane (PIB-PUR) copolymer and the porous web comprises polyethylene terephthalate.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 15, 2023
From: BOSTON SCIENTIFIC LIMITED
To: BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED
Reel/Frame 065580/0083 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 7, 2021
From: HUMAIR, ARNAUD; HEFTI, JEAN-LUC
To: BOSTON SCIENTIFIC LIMITED
Reel/Frame 056167/0482 →
Continuity (2)
Provisional Application
62940681
· Nov 26, 2019
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