IP Library Granted Patent US 12,274,582
Granted Patent B2
US 12,274,582 · App. 17/067,436 · Granted Apr 15, 2025

Ultrasound elastography method and system

Inventors: Peng Jiang (Shenzhen, CN); Shuangshuang Li (Shenzhen, CN)
Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
A61B8/485A61B8/145A61B8/4444A61B8/4494A61B8/463A61B8/5223A61B8/54A61B8/4488
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,274,582
App. No.
17/067,436
Granted
Apr 15, 2025
Kind
B2
Abstract

An ultrasound elastography method and system are provided. The method may include: exciting an ultrasound probe to transmit ultrasound waves to a body tissue under examination and receive ultrasound echoes to obtain a first ultrasound echo signal, wherein the ultrasound probe comprises an ultrasound transducer provided with multiple array elements; obtaining an ultrasound image of a body tissue under examination; displaying the ultrasound image; generating a shear waves within the body tissue under examination; exciting array elements of a ultrasound transducer to transmit the ultrasound waves to form an ultrasound beam covering a first region within the body tissue under examination; receiving the ultrasound echoes from the first region to obtain the second ultrasound echo signal; and obtaining the propagation path of the shear waves within the first region according to the second ultrasound echo signal.

Claims (47)

1. An ultrasound elastography method, comprising:

exciting an ultrasound probe to transmit ultrasound waves to a body tissue under examination and receive ultrasound echoes to obtain a first ultrasound echo signal, wherein the ultrasound probe comprises an ultrasound transducer provided with multiple array elements;

obtaining an ultrasound image of the body tissue under examination according to the first ultrasound echo signal;

generating a shear wave in the body tissue under examination;

exciting a portion of the array elements of the ultrasound transducer to transmit ultrasound waves and control an excitation time of the portion of the array elements such that the ultrasound waves transmitted by the portion of the array elements form a first unfocused ultrasound beam covering a first region in the body tissue under examination, wherein the shear wave propagates at least partially in the first region, and the first unfocused ultrasound beam tracks a propagation process of the shear wave in the first region;

receiving ultrasound echoes from the first region to obtain second ultrasound echo signals;

performing correlation calculation on the second ultrasound echo signals obtained at different times to obtain a first propagation path of the shear wave in the first region;

exciting the portion of the array elements of the ultrasound transducer to transmit ultrasound waves and control an excitation time of the portion of the array elements such that the ultrasound waves transmitted by the portion of the array elements form a second unfocused ultrasound beam covering a second region in the body tissue under examination, wherein the shear wave propagates at least partially in the second region, and the second unfocused ultrasound beam tracks a propagation process of the shear wave in the second region, wherein the first region in the body tissue under examination has a first area and the second region in the body tissue under examination has a second area, wherein the second region is different from the first region and at least partially overlaps with the first region, and the first region and the second region form a two-dimensional region;

receiving ultrasound echoes from the second region to obtain third ultrasound echo signals;

performing correlation calculation on the third ultrasound echo signals obtained at different times to obtain a second propagation path of the shear wave in the second region; and

simultaneously displaying, by a display device, the ultrasound image, the first propagation path, and the second propagation path.

2. The method of claim 1 , further comprising: calculating a first elasticity parameter in the first region based on the first propagation path of the shear wave in the first region, calculating a second elasticity parameter in the second region based on the second propagation path of the shear wave in the second region, and combining the first elasticity parameter in the first region and the second elasticity parameter in the second region to obtain an elasticity parameter representing an elasticity of the body tissue under examination in the two-dimensional region.

3. The method of claim 2 , further comprising: displaying the elasticity parameter.

4. The method of claim 2 , wherein the elasticity parameter comprises a propagation speed of the shear wave in the two-dimensional region, a Young's modulus of the body tissue under examination in the two-dimensional region, a shear modulus of the body tissue under examination in the two-dimensional region, an attenuation of the shear wave in the body tissue under examination in the two-dimensional region, or a ratio of elasticity parameters of the body tissue under examination at different positions in the two-dimensional region.

5. The method of claim 2 , further comprising: displaying, by the display device, the elasticity parameter representing the elasticity of the body tissue under examination in the two-dimensional region.

6. The method of claim 2 , further comprising: displaying, by the display device, the elasticity parameter representing the elasticity of the body tissue under examination in the two-dimensional region as a two-dimensional image.

7. An ultrasound elastography method, comprising:

generating a shear wave in a body tissue under examination;

exciting a portion of array elements of an ultrasound transducer to transmit ultrasound waves and control an excitation time of the portion of the array elements such that the ultrasound waves transmitted by the portion of the array elements form a first unfocused ultrasound beam covering a first region in the body tissue under examination, wherein the shear wave propagates at least partially in the first region, and the first unfocused ultrasound beam tracks a propagation process of the shear wave in the first region;

receiving ultrasound echoes from the first region to obtain first ultrasound echo signals;

performing correlation calculation on the first ultrasound echo signals obtained at different times to obtain a first propagation path of the shear wave in the first region;

adjusting the excitation time of the portion of the array elements in the ultrasound transducer to change a direction of the first unfocused ultrasound beam formed by the ultrasound waves transmitted by the portion of the array elements such that a second unfocused ultrasound beam formed by the ultrasound waves transmitted by the portion of the array elements covers a second region in the body tissue under examination, wherein the shear wave propagates at least partially in the second region, and the second unfocused ultrasound beam tracks a propagation process of the shear wave in the second region, wherein the first region in the body tissue under examination has a first area and the second region in the body tissue under examination has a second area, wherein the second region is different from the first region and at least partially overlaps with the first region, and the first region and the second region form a two-dimensional region;

receiving ultrasound echoes from the second region to obtain second ultrasound echo signals;

performing correlation calculation on the second ultrasound echo signals obtained at different times to obtain a second propagation path of the shear wave in the second region; and

simultaneously displaying, by a display device, an ultrasound image of the body tissue under examination, the first propagation path, and the second propagation path.

8. The method of claim 7 , further comprising:

calculating a first elasticity parameter in the first region based on the first propagation path of the shear wave in the first region, calculating a second elasticity parameter in the second region based on the second propagation path of the shear wave in the second region, and combining the first elasticity parameter in the first region and the second elasticity parameter in the second region to obtain an elasticity parameter representing an elasticity of the body tissue under examination in the two-dimensional region.

9. The method of claim 8 , further comprising: displaying, by the display device, the elasticity parameter representing the elasticity of the body tissue under examination in the two-dimensional region.

10. The method of claim 8 , further comprising: displaying, by the display device, the elasticity parameter representing the elasticity of the body tissue under examination in the two-dimensional region as a two-dimensional image.

11. The method of claim 8 , wherein the elasticity parameter comprises a propagation speed of the shear wave in the two-dimensional region, a Young's modulus of the body tissue under examination in the two-dimensional region, a shear modulus of the body tissue under examination in the two-dimensional region, an attenuation of the shear wave in the body tissue under examination in the two-dimensional region, or a ratio of elasticity parameters of the body tissue under examination at different positions in the two-dimensional region.

12. An ultrasound elastography method, comprising:

exciting an ultrasound probe to transmit ultrasound waves to a body tissue under examination and receive ultrasound echoes to obtain a first ultrasound echo signal, wherein the ultrasound probe comprises an ultrasound transducer provided with multiple array elements;

obtaining an ultrasound image of the body tissue under examination according to the first ultrasound echo signal;

determining a region of interest in the ultrasound image;

based on the determined region of interest, generating a shear wave in the body tissue under examination such that the generated shear wave at least partially propagates in the region of interest;

exciting a portion of the array elements of the ultrasound transducer to transmit ultrasound waves and controlling an excitation time of the portion of the array elements such that the ultrasound waves transmitted by the portion of the array elements form a first unfocused ultrasound beam covering a first region of the region of interest, wherein the first unfocused ultrasound beam tracks a propagation process of the shear wave in the first region of the region of interest;

receiving ultrasound echoes from the first region of the region of interest to obtain second ultrasound echo signals;

performing correlation calculation on the second ultrasound echo signals obtained at different times to obtain a first propagation path of the shear wave in the first region of the region of interest;

exciting the portion of the array elements of the ultrasound transducer to transmit ultrasound waves and controlling an excitation time of the portion of the array elements such that the ultrasound waves transmitted by the portion of the array elements form a second unfocused ultrasound beam covering a second region of the region of interest, wherein the second unfocused ultrasound beam tracks a propagation process of the shear wave in the second region of the region of interest, wherein the first region of the region of interest has a first area and the second region of the region of interest has a second area, wherein the second region is different from the first region and at least partially overlaps with the first region, and the first region and the second region form the region of interest;

receiving ultrasound echoes from the second region of the region of interest to obtain third ultrasound echo signals;

performing correlation calculation on the third ultrasound echo signals obtained at different times to obtain a second propagation path of the shear wave in the second region of the region of interest; and

simultaneously displaying, by a display device, the ultrasound image, the first propagation path, and the second propagation path.

13. The method of claim 12 , further comprising: calculating a first elasticity parameter in the first region of the region of interest based on the first propagation path of the shear wave in the first region of the region of interest, calculating a second elasticity parameter in the second region of the region of interest based on the second propagation path of the shear wave in the second region of the region of interest, and combining the first elasticity parameter in the first region and the second elasticity parameter in the second region to obtain an elasticity parameter representing an elasticity of the body tissue under examination in the region of interest.

14. The method of claim 13 , further comprising:

obtaining an elasticity image in the region of interest according to the elasticity parameter; and

displaying, by the display device, the elasticity image.

15. The method of claim 13 , wherein the elasticity parameter comprises a propagation speed of the shear wave in the region of interest, a Young's modulus of the body tissue under examination in the region of interest, a shear modulus of the body tissue under examination in the region of interest, an attenuation of the shear wave in the body tissue under examination in the region of interest or a ratio of elasticity parameters of the body tissue under examination at different positions in the region of interest.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2020
From: JIANG, PENG; LI, SHUANGSHUANG
To: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 054033/0600 →
Continuity (2)
Continuation PCTCN2018082691 · Apr 11, 2018
Related Publication 20210022711A1 · Jan 28, 2021
References Cited (31)
US 11172910B2 · Greenleaf et al. · 2021 [cited by applicant]
US 20080249408A1 · Palmeri · 2008 [cited by examiner]
US 20090216119A1 · Fan et al. · 2009 [cited by applicant]
US 20100016718A1 · Fan et al. · 2010 [cited by applicant]
US 20110263978A1 · Chen · 2011 [cited by examiner]
US 20130131511A1 · Peterson et al. · 2013 [cited by applicant]
US 20130218012A1 · Specht · 2013 [cited by examiner]
US 20130317361A1 · Tabaru et al. · 2013 [cited by applicant]
US 20160143621A1 · Parthasarathy et al. · 2016 [cited by applicant]
US 20160262706A1 · Zhao · 2016 [cited by examiner]
US 20190046160A1 · Li et al. · 2019 [cited by applicant]
US 20190192120A1 · Choi · 2019 [cited by examiner]
US 20190314002A1 · Peterson et al. · 2019 [cited by applicant]
US 20200187910A1 · Pinton · 2020 [cited by examiner]
CN 102283679A · 2011 [cited by applicant]
CN 102667522A1 · 2012 [cited by applicant]
CN 103347450A · 2013 [cited by applicant]
CN 103492855A · 2014 [cited by applicant]
CN 105395218A · 2016 [cited by applicant]
CN 105491959A · 2016 [cited by applicant]
CN 105877783A · 2016 [cited by applicant]
CN 205697832U · 2016 [cited by applicant]
CN 106456108A · 2017 [cited by applicant]
CN 107510474A · 2017 [cited by applicant]
JP 2015188514A · 2015 [cited by applicant]
WO 2016033752A1 · 2016 [cited by applicant]
Chen S, Urban MW, Pislaru C, Kinnick R, Zheng Y, Yao A, Greenleaf JF. Shearwave dispersion ultrasound vibrometry (SDUV) for measuring tissue elasticity and viscosity. IEEE Trans Ultrason Ferroelectr Freq Control. Jan. 2… [cited by examiner]
PCT International Search Report and the Written Opinion mailed Jan. 14, 2019, issued in related International Application No. PCT/CN2018/082691, with partial English translation (11 pages). [cited by applicant]
PCT International Preliminary Report on Patentability mailed Oct. 22, 2020, issued in related International Application No. PCT/CN2018/082691, with English translation (10 pages). [cited by applicant]
First Search dated Oct. 18, 2021, issued in related Chinese Application No. 201880016644.6 (2 pages). [cited by applicant]
First Office Action dated Oct. 26, 2021, issued in related Chinese Application No. 201880016644.6, with English machine translation (23 pages). [cited by applicant]