IP Library Granted Patent US 12,280,348
Granted Patent B2
US 12,280,348 · App. 17/391,352 · Granted Apr 22, 2025

Aerogel based on gas vesicles and bacterial cellulose

Inventor: Lina Gonzalez (Worcester, MA)
B01J13/0091C08L1/02C09D101/08C12P19/04C12P21/00C07K2319/20C08L101/12C12N2501/998C12R2001/02C12R2001/89
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Quick Facts
Patent No.
US 12,280,348
App. No.
17/391,352
Granted
Apr 22, 2025
Kind
B2
Abstract

A material with a scaffold comprising a series of at least partially spaced fibers and gas vesicles locates between fibers. The gas vesicles comprise external anchoring modules that are effective to anchor the gas vesicles to the fibers.

Claims (7)

1. A material comprising:

a scaffold comprising a series of at least partially spaced bacterial-derived cellulose fibers produced by genetically modified G. xylinus bacteria with an upregulated dgc gene; and

bacterial-derived gas vesicles produced by a-genetically modified B. subtilis bacteria and comprising GvpA and GvpC proteins, and located between fibers, wherein the gas vesicles comprise integral external anchoring modules that comprise cellulose binding modules that comprise CBM48, wherein the external anchoring modules are effective to link the gas vesicles to the bacterial cellulose fibers:

wherein at least some of the gas vesicles have lengths from 0.1 to 2 microns.

2. The material of claim 1 , comprising an aerogel.

3. The material of claim 1 , wherein the gas vesicles further comprise a bacterial-derived external hydrophobicity coating that comprises the BslA protein.

4. The material of claim 1 , wherein the cellulose fibers further comprise bacterial-derived melanin to provide fire resistance.

Continuity (2)
Provisional Application 63059303 · Jul 31, 2020
Related Publication 20220401908A1 · Dec 22, 2022
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Cited By (1)
US 12,735,674