IP Library › Granted Patent US 12,295,909
Granted Patent B2
US 12,295,909 · App. 18/501,446 · Granted May 13, 2025

Adapter for use in a planetary mixer

Inventor: Panagiota Danopoulos (St-Laurent, CA)
Assignee: MEDISCA PHARMACEUTIQUE INC
A61J1/05A61J3/04A61K9/0034A61K9/06A61K9/107A61K31/045A61K31/135A61K31/137A61K31/192A61K31/195A61K31/196A61K31/197A61K31/351A61K31/4418A61K31/4422A61K31/445A61K31/4458A61K31/565A61K31/57A61K31/7048A61K33/14A61K47/10A61K47/26A61K47/38A61K47/42A61K47/46B01F29/10B01F29/32B01F29/40B01F29/4011B01F29/40221B01F31/00B01F35/2209B01F35/421B29B7/106B65B7/16B01F29/40365
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Quick Facts
Patent No.
US 12,295,909
App. No.
18/501,446
Granted
May 13, 2025
Kind
B2
Abstract

A dispensing container and adapter system for use with a planetary mixer is disclosed. The dispensing container has a longitudinal axis and a transverse axis. The dispensing container may include a nozzle and a removable cap to cover the nozzle. The removable cap may have a first width dimension measured along the transverse axis. The dispensing container may include a body having a second width dimension measured along the transverse axis. An adapter may receive the dispensing container. The adapter may include a cavity to receive the removable cap. The cavity may have a cavity width that exceeds the first width dimension. The adapter may also include a recess for receiving a portion of the dispensing container. The recess may extend from the cavity. At least a portion of the recess may have a width dimension smaller than both the first width dimension and the second width dimension.

Claims (43)

1. A method of preparing a composition comprising:

creating a pharmaceutical composition in a bladeless planetary mixer,

wherein the composition is held within a container and includes a gelatin-based material; and

mixing the composition in the bladeless planetary mixer using superimposed revolution and rotation movements performed on the container using determined parameters to increase the temperature of the gelatin-based material to at least 50.5° C. and not greater than 72.8° C. to melt the gelatin-based material.

2. The method of claim 1 , wherein the composition includes an active pharmaceutical ingredient (API).

3. The method of claim 1 , wherein the container is a dispenser, and the dispenser is located within a jar.

4. The method of claim 3 , further comprising securing the dispenser within the jar using an adapter.

5. The method of claim 4 , wherein the adapter includes:

a central opening configured to receive at least a portion of the container; and

a circumferential outer wall at least a portion of which is configured to abut an inner wall of the jar.

6. The method of claim 1 , further comprising pouring the composition into a mold having a desired shape.

7. The method of claim 6 , wherein the desired shape of the mold is in a form of a troche, a suppository, or a throat lozenge.

8. The method of claim 6 , further comprising cooling the composition to obtain a solid or chewable composition.

9. The method of claim 1 , wherein the determined parameters include a revolution speed of the planetary mixer and a processing time.

10. The method of claim 9 , wherein the processing time is between 20 and 900 seconds.

11. The method of claim 10 , wherein the revolution speed is at least 400 revolutions per minute.

12. A method of preparing a composition comprising:

placing the composition including a gelatin gum base material in a container;

securing the container within a bladeless planetary mixer; and

mixing the composition using the bladeless planetary mixer, based on first determined parameters to generate a melt of the gelatin gum base material by increasing the temperature of the composition to at least 50.5° C. and not greater than 72.8° C. without requiring the addition of external heat to achieve the melt.

13. The method of claim 12 , wherein the planetary mixer is configured to superimpose revolution and rotation movements on the container.

14. The method of claim 12 , wherein securing the container includes securing the container inside of a jar using an adapter.

15. The method of claim 14 , wherein the adapter includes:

a circumferential outer wall at least a portion of which is configured to abut an inner wall of the jar; and

a central opening configured to receive at least a portion of the container.

16. The method of claim 12 , further comprising pouring the composition into a mold having a desired shape.

17. The method of claim 16 , wherein the desired shape of the mold is in a form of a troche, a suppository, or a throat lozenge.

18. The method of claim 12 , wherein first determined parameters include a revolution speed of the bladeless planetary mixer and a processing time.

19. The method of claim 18 , wherein the processing time is 180 seconds.

20. A method of preparing a composition comprising:

placing contents, including at least one active ingredient and a gelatin gum base material, in a container;

securing the container in a jar with an adapter such that at least a portion of the container is disposed outside the adapter;

inserting the jar into a bladeless planetary mixer; and

subjecting the jar to movements with the bladeless planetary mixer based on determined parameters to generate a melt of the gelatin gum base material without requiring the addition of external heat to achieve the melt.

21. The method of claim 20 , wherein the planetary mixer is configured to subject the jar to superimposed revolution and rotation movements.

22. The method of claim 20 , wherein the adapter includes at least one recess configured to receive the container.

23. The method of claim 22 , wherein the at least one recess is concentric with the jar.

24. The method of claim 20 , wherein melting of the contents occurs at a temperature below a molten transition temperature of the contents.

25. The method of claim 20 , wherein the determined parameters include a revolution speed of the planetary mixer and a processing time.

26. The method of claim 25 , wherein the processing time is between 20 and 900 seconds.

27. The method of claim 25 , wherein the revolution speed is at least 400 revolutions per minute.

28. The method of claim 20 , wherein the active ingredient is an active pharmaceutical ingredient (API).

29. The method of claim 12 , wherein the gelatin gum base material includes gelatin gum base particles.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2023
From: DANOPOULOS, PANAGIOTA
To: MEDISCA PHARMACEUTIQUE INC.
Reel/Frame 065451/0631 →
Continuity (6)
Continuation 17123442 · Dec 16, 2020
Continuation 16372006 · Apr 1, 2019
Continuation 16131986 · Sep 14, 2018
Continuation 15809636 · Nov 10, 2017
Provisional Application 62420426 · Nov 10, 2016
Related Publication 20240108543A1 · Apr 4, 2024
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