IP Library Granted Patent US 12,324,934
Granted Patent B2
US 12,324,934 · App. 18/090,684 · Granted Jun 10, 2025

Neutron dose measurement apparatus and neutron capturing treatment device

Inventors: Yuan-Hao Liu (Fujian, CN); Chao Wang (Fujian, CN)
Assignee: NEUBORON THERAPY SYSTEM LTD.
A61N5/1077A61N5/1048A61N5/1065A61N5/1067A61N5/1071A61N2005/1074A61N2005/109A61N2005/1092A61N2005/1095
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Quick Facts
Patent No.
US 12,324,934
App. No.
18/090,684
Granted
Jun 10, 2025
Kind
B2
Abstract

Disclosed are a neutron dose measurement apparatus and a neutron capturing treatment device. The neutron dose measurement apparatus includes a measurement unit for receiving neutrons and outputting signals, a signal processing unit for processing the signals output from the measurement unit, a counter for counting the signals output from the signal processing unit to obtain a count rate, and a count rate correction unit for correcting the count rate.

Claims (147)

1. A neutron dosage detection apparatus, comprising

a detector configured to detect a neutron and output a signal,

a signal processing unit configured to process the signal output from the detector,

a counter configured to count a signal output from the signal processing unit to obtain a counting rate, and

a counting rate correction unit configured to correct the counting rate, wherein the counting rate correction unit calculates a corrected counting rate C k by using formulas (1-1) and (1-2):

C

k

=

K

·

C

t

(

1

1

)

K

=

m

n

(

1

2

)

where K is a counting rate correction factor, C t is a real-time counting rate recorded by the counter, n is the number of pulses recorded by the counter in unit time, and m is the number of signal pulses actually generated within the detector in unit time.

2. The neutron dosage detection apparatus of claim 1 , wherein the counting rate correction unit derives a formula (1-4) by combining the formula (1-2) with the formula (1-3), to calculate the counting rate correction factor K:

m

-

n

=

nm

τ

(

1

3

)

K

=

1

1

-

n

τ

(

1

4

)

where τ is a pulse resolution time.

3. The neutron dosage detection apparatus of claim 2 , wherein the counting rate correction unit calculates the pulse resolution time τ by using a formula (1-5):

τ

=

I

2

I

1

·

C

1

-

C

2

I

2

I

1

·

C

1

·

C

2

(

1

-

5

)

where I 1 is a first neutron beam flux, C 1 is a counting rate recorded by the counter when a neutron beam flux is I 1 , I 2 is a second neutron beam flux, C 2 is a counting rate recorded by the counter when a neutron beam flux is I 2 .

4. The neutron dosage detection apparatus of claim 1 , wherein the detector comprises one or more of a He-3 proportional counter, a BF 3 proportional counter, a fission chamber, a boron ionization chamber or a scintillator detector.

5. The neutron dosage detection apparatus of claim 1 , further comprising a conversion unit configured to convert the counting rate into a neutron flux rate or a neutron dosage rate, and an integration unit configured to integrate the neutron flux rate or the neutron dosage rate to obtain a neutron dosage.

6. The neutron dosage detection apparatus of claim 5 , further comprising a display configured to display the neutron dosage.

7. A neutron capture therapy device, comprising the neutron dosage detection apparatus of claim 1 .

8. The neutron capture therapy device of claim 7 , comprising a neutron beam irradiation system, the neutron beam irradiation system comprises a neutron beam generation module configured to generate a neutron beam, and a beam adjustment module configured to adjust the neutron beam and comprising a retarder configured to decelerate the neutron beam and a reflector configured to guide a deviated neutron back to the retarder.

9. The neutron capture therapy device of claim 7 , wherein the counting rate correction unit derives a formula (1-4) by combining the formula (1-2) with the formula (1-3), to calculate the counting rate correction factor K:

m

-

n

=

nm

τ

(

1

3

)

K

=

1

1

-

n

τ

(

1

4

)

where τ is a pulse resolution time.

10. The neutron capture therapy device of claim 9 , wherein the counting rate correction unit calculates the pulse resolution time t by using a formula (1-5):

τ

=

I

2

I

1

·

C

1

-

C

2

I

2

I

1

·

C

1

·

C

2

(

1

5

)

where I 1 is a first neutron beam flux, C 1 is a counting rate recorded by the counter when a neutron beam flux is I 1 , I 2 is a second neutron beam flux, C 2 is a counting rate recorded by the counter when a neutron beam flux is I 2 .

11. The neutron capture therapy device of claim 7 , wherein the detector comprises one or more of a He-3 proportional counter, a BF 3 proportional counter, a fission chamber, a boron ionization chamber or a scintillator detector.

12. The neutron capture therapy device of claim 7 , further comprising a conversion unit configured to convert the counting rate into a neutron flux rate or a neutron dosage rate, and an integration unit configured to integrate the neutron flux rate or the neutron dosage rate to obtain a neutron dosage.

13. The neutron capture therapy device of claim 12 , further comprising a display configured to display the neutron dosage.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 29, 2022
From: LIU, YUAN-HAO; WANG, CHAO
To: NEUBORON THERAPY SYSTEM LTD.
Reel/Frame 062233/0939 →
Priority Claims (2)
CN 202010631538.8 · Jul 3, 2020 · national
CN 202011060387.1 · Sep 30, 2020 · national
Continuity (2)
Continuation PCTCN2021104168 · Jul 2, 2021
Related Publication 20230137634A1 · May 4, 2023
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