IP Library Granted Patent US 10,737,121
Granted Patent B2
US 10,737,121 · App. 16/662,523 · Granted Aug 11, 2020

Neutron source for neutron capture therapy

Inventors: Melvin Arthur Piestrup (Redwood City, CA); Craig Mathew Brown (Santa Clara, CA); Allan Xi Chen (Daly City, CA); Charles Kevin Gary (Palo Alto, CA); Yao Zong Guan (San Francisco, CA); Yoshio Horii (Fukushima, JP); Glenn Emerson Jones, Jr. (Pittsburg, CA); Yuji Kokubo (Fukushima, JP); Naoyuki Yamada (Fukushima, JP); Shotaro Komura (Fukushima, JP)
Assignee: Adelphi Technology, Inc.
A61N5/1077A61N5/10G21G4/02A61N2005/109A61N2005/1094A61N2005/1095
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Quick Facts
Patent No.
US 10,737,121
App. No.
16/662,523
Granted
Aug 11, 2020
Kind
B2
Abstract

A neutron generator has a pre-moderator block of moderating material, an acceleration chamber, a vacuum pump evacuating the acceleration chamber to a moderately high vacuum, a plasma ion chamber opening into the acceleration chamber through an ion extraction iris, a gas source providing deuterium gas to the plasma ion chamber, a microwave energy source ionizing the gas in the plasma ion chamber, a primary and a secondary isolation well extending into the pre-moderator block, a water-cooled titanium target disk positioned at a lower extremity of the primary isolation well, the target disk biased to a substantial negative DC voltage, and electrically grounded metal cladding covering surfaces of the pre-moderator block. Ions extracted through the ion extraction iris are accelerated to bombard the titanium target producing energetic neutrons that pass through and are moderated by the pre-moderator block.

Claims (17)

1. A neutron generator, comprising:

a pre-moderator block of moderating material having an upper surface, a lower surface, a first and a second end, first and second side surfaces, a first length, a first width less than the first length, and a first thickness;

a cylindrical acceleration chamber having a first diameter the first width of the pre-moderator block, sealed at one end to the upper surface of the pre-moderator block adjacent the first end of the pre-moderator block, with a vertical axis perpendicular to the upper surface, the acceleration chamber having a height and a top cover at a second end away from the pre-moderator block;

a vacuum pump engaging the acceleration chamber, evacuating the acceleration chamber to a high vacuum;

a plasma ion chamber opening into the acceleration chamber through an ion extraction iris through the top cover of the acceleration chamber on the vertical axis of the acceleration chamber;

a gas source providing deuterium gas to the plasma ion chamber;

a microwave energy source ionizing the gas in the plasma ion chamber;

a cylindrical primary isolation well extending a distance into the pre-moderator block from the upper surface, centered on the vertical axis of the acceleration chamber;

a secondary isolation well in a shape of a hollow cylinder surrounding the primary isolation well, to a depth somewhat less than the distance of the primary isolation well, within the first diameter of the acceleration chamber;

a water-cooled titanium target disk having a target surface orthogonal to the axis of the acceleration chamber, the target disk having a diameter smaller than a diameter of the isolation well, positioned at a lower extremity of the isolation well, the target disk biased to a negative DC voltage; and electrically grounded metal cladding covering all otherwise exposed surfaces of the pre-moderator block;

wherein ions extracted through the ion extraction iris are accelerated to bombard the titanium target at the lower extremity of the primary isolation well, producing energetic neutrons that pass through and are moderated by the pre-moderator block, and wherein any path along a surface from the titanium target to an electrically grounded element is necessarily maximized by the primary and secondary isolation wells.

2. The neutron generator of claim 1 wherein the material of the pre-moderator block is Ultra-High-Molecular-Weight Polyethylene (UHMWPE), or High-Density Polyethylene (HDPE), or polytetrafluoroethene (PTFE).

3. The neutron generator of claim 2 wherein surfaces of the primary and secondary isolation wells are formed in continuous curves and are roughened to enhance resistance to high-voltage flashover.

4. The neutron generator of claim 1 further comprising supply and return water channels lengthwise through the pre-moderator block from the second end of the pre-moderator block to the titanium target, providing cooling water cooling the target.

5. The neutron generator of claim 1 further comprising a female socket for a high-voltage male connector at the second end of the pre-moderator block, coupled to a high-voltage bus bar implemented lengthwise through the pre-moderator block, to the target, for biasing the target to a negative DC voltage.

6. The neutron generator of claim 1 wherein both the first and second side surfaces of the pre-moderator block are angled inward from vertical by thirty degrees for at least a portion of the height, enabling six neutron generators to be placed with the angled side surfaces fully adjacent, forming a closed ring about a center point.

7. The neutron generator of claim 1 wherein both the first and second side surfaces of the pre-moderator block are angled inward from vertical by forty-five degrees for at least a portion of the height, enabling eight neutron generators to be placed with the angled side surfaces fully adjacent, forming a closed ring about a center point.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2019
From: GUAN, YAO ZONG
To: ADELPHI TECHNOLOGY, INC.; FUKUSHIMA SIC APPLIED ENGINEERING INC.
Reel/Frame 051065/0269 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2019
From: PIESTRUP, MELVIN ARTHUR; BROWN, CRAIG MATHEW; CHEN, ALLAN XI; GARY, CHARLES KEVIN; HORII, YOSHIO; JONES, GLENN EMERSON, JR; KOKUBO, YUJI; YAMADA, NAOYUKI; KOMURA, SHOTARO
To: ADELPHI TECHNOLOGY, INC.; FUKUSHIMA SIC APPLIED ENGINEERING INC.
Reel/Frame 050816/0172 →
Continuity (6)
Continuation In Part 15488983 · Apr 17, 2017
Continuation 14190389 · Feb 26, 2014
Continuation 13532447 · Jun 25, 2012
Provisional Application 61571406 · Jun 27, 2011
Provisional Application 62749875 · Oct 24, 2018
Related Publication 20200069974A1 · Mar 5, 2020
Cited By (1)
US 12,245,355