Sample container with peelable seal and access port
An apparatus includes a flexible container and a port. The container includes a first layer coupled to a second layer to define a storage volume within which a tissue specimen can be contained. The first layer has a first stiffness and the second layer has a second stiffness. An edge of the first layer is spaced apart from an edge of the second layer to define an opening into the storage volume. The edges of the first and second layer form a peelable seal that hermetically seals the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume. The port is coupled to the flexible container and allows fluid communication between the storage volume and an external volume.
1. An apparatus, comprising:
a flexible container including a first layer coupled to a second layer to define a storage volume within which a tissue specimen can be contained, an edge of the first layer spaced apart from an edge of the second layer to define an opening into the storage volume, the edge of the first layer extends along a longitudinal axis of the flexible container, the edge of the second layer extends along the longitudinal axis, the edge of the first layer and the edge of the second layer configured to form a peelable seal that hermetically seals the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume; and
a support structure configured to support the tissue specimen on a condition that the tissue specimen is within the storage volume.
2. The apparatus of claim 1 , wherein:
the first layer is characterized by a first stiffness;
the second layer is characterized by a second stiffness;
the support structure is characterized by a third stiffness; and
the third stiffness greater than the first stiffness and the second stiffness.
3. The apparatus of claim 1 , wherein:
the first layer is a first laminate including a first substrate, a first barrier coating, and a first adhesive, the first substrate being a peelable film; and
the second layer is a second laminate including a second substrate, a second barrier coating, and a second adhesive, the second substrate being a different material than the first substrate.
4. The apparatus of claim 1 , wherein:
the flexible container includes a third layer coupled to a first longitudinal edge of the second layer and to a second longitudinal edge of the second layer to define a separate volume;
the second layer is between the first layer and the third layer; and
the separate volume is aligned with the storage volume.
5. The apparatus of claim 4 , wherein:
an edge of the third layer is sealed to the edge of the second layer to seal the separate volume.
6. The apparatus of claim 4 , wherein:
the separate volume is sized to receive the support structure; and
the separate volume is sealed on a condition that the support structure is positioned therein.
7. The apparatus of claim 1 , wherein:
the support structure is positioned within the storage volume; and
the support structure defines a series of hydration openings.
8. The apparatus of claim 1 , wherein:
the support structure includes a first end portion, a second end portion, a bottom surface, and a raised side edge;
the raised side edge extends away from the bottom surface; and
the raised side edge is parallel to the longitudinal axis of the flexible container the condition that the tissue specimen is within the storage volume.
9. The apparatus of claim 8 , wherein:
the bottom surface is configured to receive the tissue specimen;
the raised side edge surrounds the tissue specimen on a condition that the tissue specimen is on the bottom surface; and
the raised side edge is configured to maintain the tissue specimen on the bottom surface during a movement of the support structure.
10. The apparatus of claim 8 , wherein:
the raised side edge increases a cross-sectional area moment of inertia of the support structure relative to a planar support structure.
11. The apparatus of claim 8 , wherein:
the first end portion of the support structure includes a manipulation tab; and
the manipulation tab includes an indicium associated with the tissue specimen.
12. The apparatus of claim 1 , further comprising:
a port coupled to the flexible container, the port configured to allow fluid communication between the storage volume and an external volume, the port is coupled at an end of the flexible container, a center line of the port being aligned with the longitudinal axis of the flexible container, the center line of the port being parallel to the opening defined by the edge of the first layer and the edge of the second layer.
13. An apparatus, comprising:
a flexible container including a first layer, a second layer, and a third layer, the second layer positioned between the first layer and the third layer, the first layer coupled to the second layer to define a storage volume within which a tissue specimen can be contained, the third layer coupled to the second layer to define a separate volume that is isolated from the storage volume by the second layer, an edge of the first layer spaced apart from an edge of the second layer to define an opening into the storage volume, the edge of the first layer and the edge of the second layer having a peelable seal suitable to hermetically seal the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume; and
a support structure configured to support the tissue specimen on a condition that the tissue specimen is within the storage volume.
14. The apparatus of claim 13 , wherein:
the first layer is coupled to a first longitudinal edge of the second layer and to a second longitudinal edge of the second layer;
the third layer is coupled to the first longitudinal edge of the second layer and to the second longitudinal edge of the second layer; and
an edge of the third layer is sealed to the edge of the second layer to seal the separate volume.
15. A method, comprising:
inserting a tissue specimen into a storage volume defined between a first layer of a flexible container and a second layer of the flexible container, the tissue specimen being inserted via an opening defined by an edge of the first layer and an edge of the second layer, the edge of the first layer and the edge of the second layer extending along a longitudinal axis of the flexible container, the tissue specimen being supported within the storage volume via a support structure of the flexible container; and
coupling the edge of the first layer to the edge of the second layer to form a peelable seal that hermetically seals the storage volume, the peelable seal configured such that the first layer can be peeled away from the second layer to expose the storage volume.
16. The method of claim 15 , wherein:
the flexible container includes a third layer coupled to a first longitudinal edge of the second layer and to a second longitudinal edge of the second layer to define a separate volume; and
the support structure is within the separate volume.
17. The method of claim 16 , wherein:
an edge of the third layer is sealed to the edge of the second layer to seal the separate volume on a condition that the support structure is within the separate volume; and
the edge of the second layer is between the edge of the first layer and the edge of the third layer.
18. The method of claim 15 , wherein inserting the tissue specimen into the storage volume includes:
positioning the tissue specimen on a bottom surface of the support structure, a raised side edge of the support structure surrounding the tissue specimen on the bottom surface; and
manipulating the support structure via a manipulation tab to move the support structure and the tissue specimen to a position within the storage volume, the manipulation tab including an indicium associated with the tissue specimen.
19. The method of claim 18 , wherein:
the bottom surface defines a series of hydration openings; and
the method includes exposing a portion of the tissue specimen facing the bottom surface to a fluid via the series of hydration openings.
20. The method of claim 15 , further comprising:
conveying, after the coupling, a fluid into the storage volume via a port configured to allow fluid communication between the storage volume and an external volume, the port being coupled at an end of the flexible container, a center line of the port being aligned with the longitudinal axis of the flexible container, the center line of the port being parallel to the opening defined by the edge of the first layer and the edge of the second layer.