IP Library › Granted Patent US 12,337,130
Granted Patent B2
US 12,337,130 · App. 17/533,308 · Granted Jun 24, 2025

Suppository insertion device, suppository, and method of manufacturing a suppository

Inventors: Jennifer J. Davagian (Acton, MA); Mark C. Ensign (Sudbury, MA)
Assignee: Cristcot LLC
A61M31/007A45D40/16A61B50/30A61J3/08A45D40/00A45D40/08A45D40/12A45D2040/202A61K9/0031A61K9/025
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Quick Facts
Patent No.
US 12,337,130
App. No.
17/533,308
Granted
Jun 24, 2025
Kind
B2
Abstract

Today's suppositories are typically packaged individually for digital administration into the anal canal of a patient. A suppository applicator described herein, which works with individually packaged suppositories, can alternatively be shipped in a prepackaged operational arrangement with a suppository to enable the patient to administer the suppository through use of the applicator in a single operation after opening a hygienic wrapper containing the applicator-suppository combination. A method for manufacturing a suppository includes manufacturing the suppository in the presence of and in contact with an element configured to be used to insert the suppository into a body cavity. The method may include using the element to define a shape of the suppository during the manufacturing. The resulting applicator-suppository combination is more hygienic and easier to handle than the separate applicator and suppository and provides more efficiency from time of opening the packaging to time of commencing administration of the suppository.

Claims (15)

1. A suppository comprising:

an active ingredient; and

an inactive agent used to define a solid geometrical shape containing the active ingredient, the solid geometrical shape defining at least one gas flow path.

2. The suppository of claim 1 , wherein the inactive agent is an inert agent.

3. The suppository of claim 1 , wherein the gas flow path is arranged to communicate with a gas flow path of an element configured to be employed to insert the suppository into a body cavity.

4. The suppository of claim 1 , wherein the suppository is manufactured in the presence of and in contact with an element configured to be employed to insert the suppository into a body cavity.

5. The suppository of claim 1 , wherein the suppository is a solid or semi-solid suppository.

6. The suppository of claim 5 , wherein the active ingredient is a pharmacological agent for treating a digestive disease.

7. The suppository of claim 6 , wherein the digestive disease is ulcerative proctitis or distal colitis.

8. The suppository of claim 1 , wherein the solid geometrical shape comprises a first open end and a second open end, the at least one gas flow path extending through the solid geometrical shape from the first open end to the second open end.

9. The suppository of claim 8 , wherein the solid geometrical shape is rounded at the first open end and the second open end.

10. The suppository of claim 1 , wherein solid geometrical shape is cylindrical.

11. The suppository of claim 1 , wherein the solid geometrical shape is a hollow bullet shape comprising an open space defining the at least one gas flow path.

12. The suppository of claim 1 , wherein the inactive agent is an oil-based fat or a polyethylene glycol.

13. The suppository of claim 5 , wherein the active ingredient is a pharmacological agent for treating hemorrhoids.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 29, 2021
From: DAVAGIAN, JENNIFER J.; ENSIGN, MARK C.
To: CRISTCOT LLC
Reel/Frame 058224/0923 →
Continuity (5)
Division 16197005 · Nov 20, 2018
Division 14436359
Provisional Application 61807915 · Apr 3, 2013
Provisional Application 61716212 · Oct 19, 2012
Related Publication 20220088358A1 · Mar 24, 2022
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