IP Library › Granted Patent US 12,360,193
Granted Patent B2
US 12,360,193 · App. 18/147,418 · Granted Jul 15, 2025

Modularized multi-purpose magnetic resonance phantom

Inventors: Hung-Yu Lin (Walnut Creek, CA); Donghui Yin (San Francisco, CA); Nguyen Pham (San Francisco, CA); Sree Poojitha Yerramsetti (San Francisco, CA); Randy Link (El Cerrito, CA); Nio Anderson (San Francisco, CA); Rishabh Ostawal (San Francisco, CA); Joyce Ye (San Francisco, CA); Guanhao Fu (Richmond, CA); Ghoncheh Amouzandeh (Alameda, CA); Xiaowei Zou (San Francisco, CA)
Assignee: neuro42, Inc.
G01R33/58G01R33/5608A61B5/055
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Quick Facts
Patent No.
US 12,360,193
App. No.
18/147,418
Granted
Jul 15, 2025
Kind
B2
Abstract

The present disclosure provides magnetic resonance phantom imaging phantoms and method of assembling thereof. In one aspect, a magnetic resonance imaging phantom can include a plurality of modular components. The plurality of modular components can include a first modular component, a second modular component, a shell, and a lid. The second modular component can be different than the first modular component. The shell can be structured to receive at least one modular component. The lid can be attachable to the shell to enclose the at least one modular component received within the shell.

Claims (30)

1. A method of assembling a magnetic resonance imaging phantom, comprising:

selecting at least two components from a kit for a first calibration;

assembling the at least two components to form a first configuration of the magnetic resonance imaging phantom;

performing the first calibration with the first configuration of the magnetic resonance imaging phantom;

disassembling the first configuration of magnetic resonance imaging phantom;

selecting at least two modular components from the kit for a second calibration;

assembling the at least two modular components to form a second configuration of the magnetic resonance imaging phantom, wherein the second configuration is different than the first configuration; and

performing the second calibration with the magnetic resonance imaging phantom.

2. A magnetic resonance imaging phantom kit, comprising:

a shell comprising shell interlocking features;

a first modular component, wherein the first modular component comprises first interlocking features configured to interlock with the shell interlocking features in different configurations; and

a second modular component, wherein the second modular component is different than the first modular component, wherein the second modular component comprises second interlocking features configured to interlock with the shell interlocking features in different configurations, and wherein at least one of the first modular component and the second modular component comprises a contrast insert configured to receive a contrast medium, wherein the first modular component and the second modular component are selected for validation of two or more properties selected from a group consisting of geometric distortion, contrast, structure, signal-to-noise, resolution, and intracranial vascular flow.

3. A magnetic resonance imaging phantom kit, comprising:

a shell comprising shell interlocking features;

a first modular component, wherein the first modular component comprises first interlocking features configured to interlock with the shell interlocking features in different configurations; and

a second modular component, wherein the second modular component is different than the first modular component, wherein the second modular component comprises second interlocking features configured to interlock with the shell interlocking features in different configurations, and wherein at least one of the first modular component and the second modular component comprises a contrast insert configured to receive a contrast medium, wherein the first modular component and the second modular component are selectively arranged for acquiring imaging data in low-field strength magnetic fields generated by a magnet assembly.

4. The method of claim 1 , wherein performing the first calibration comprises obtaining imaging data in a low-field strength magnetic field.

5. The method of claim 1 , wherein the first configuration is customized for a first magnetic resonance imaging system, and wherein the second configuration is customized for a second magnetic resonance imaging system.

6. The method of claim 1 , wherein the first configuration is customized for a first magnetic field strength, and wherein the second configuration is customized for a second magnetic field strength.

7. The method of claim 1 , wherein the first configuration is selected for validation of two or more properties selected from a group consisting of geometric distortion, contrast, structure, signal-to-noise, resolution, and intracranial vascular flow.

8. The method of claim 1 , wherein the first configuration is customized for diffusion-weighted imaging.

9. The method of claim 1 , wherein the at least two components selected for the second calibration are different than the at least two components selected for the first calibration.

10. The method of claim 1 , wherein the at least two components selected for the second calibration are the same as the at least two components selected for the first calibration.

11. The magnetic resonance imaging phantom kit of claim 2 , further comprising a third modular component comprising third interlocking features configured to interlock with the shell interlocking features in different configurations.

12. The magnetic resonance imaging phantom kit of claim 2 , wherein the contrast insert comprises a refillable tube.

13. The magnetic resonance imaging phantom kit of claim 2 , wherein the contrast medium is selected from a group consisting of nickel chloride, sodium chloride, copper sulfate, and gadolinium chloride.

14. The magnetic resonance imaging phantom kit of claim 2 , wherein the different configurations correspond to different main magnetic field strength applications.

15. The magnetic resonance imaging phantom kit of claim 2 , wherein the different configurations correspond to different geometric form factors for different magnetic resonance systems.

16. The magnetic resonance imaging phantom kit of claim 2 , wherein the first modular component and the second modular component are selectively arranged for diffusion-weighted imaging.

17. The magnetic resonance imaging phantom kit of claim 2 , wherein the first modular component and the second modular component are selectively arranged for acquiring imaging data in low-field strength magnetic fields generated by a magnet assembly.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2025
From: OSTAWAL, RISHABH
To: NEURO42, INC.
Reel/Frame 071547/0164 →
Continuity (1)
Related Publication 20240219504A1 · Jul 4, 2024
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Cited By (2)
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