IP Library › Granted Patent US 12,391,968
Granted Patent B2
US 12,391,968 · App. 17/599,847 · Granted Aug 19, 2025

Production method for rare fatty acid using novel enzyme, and novel rare fatty acid

Inventors: Jun Ogawa (Kyoto, JP); Shigenobu Kishino (Kyoto, JP); Kohey Kitao (Kyoto, JP)
Assignee: NOSTER INC.
C12P7/6427C07C59/42C12N9/88C12N15/70
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Quick Facts
Patent No.
US 12,391,968
App. No.
17/599,847
Granted
Aug 19, 2025
Kind
B2
Abstract

A method for producing a hydroxylated fatty acid by a hydration reaction using a novel enzyme derived from the genus Clostridium in the soil and using fatty acid as a substrate is provided by the present invention. In addition, a novel rare fatty acid with utility value which is obtained by the production method is also provided.

Claims (9)

1. A hydroxylated or oxo fatty acid selected from the group consisting of 11-hydroxy-cis-4,cis-7,cis-13,cis-16,cis-19-docosapentaenoic acid, 11-hydroxy-cis-7,cis-13,cis16,cis-19-docosatetraenoic acid, 12-hydroxycis-5,cis-8,cis-14,cis-17-eicosatetraenoic acid, 11-oxo-cis-4, cis-7,cis-13,cis-16,cis-19-docosapentaenoic acid, 11-oxo-cis-7,cis-13,cis-16,cis-19-docosatetraenoic acid, and 12-oxo-cis5,cis-8,cis-14,cis-17-eicosatetraenoic acid.

2. A fatty acid-containing material comprising the hydroxylated or oxo fatty acid according to claim 1 and one or more additives.

3. A fatty acid-containing material comprising the hydroxylated or oxo fatty acid according to claim 1 blended with a pharmaceutical composition, a food or food additive, a cosmetic or cosmetic additive, or a feed or feed additive.

4. The hydroxylated or oxo fatty acid of claim 1 that is 11-hydroxy-cis-4,cis-7,cis-13,cis-16,cis-19-docosapentaenoic acid.

5. The hydroxylated or oxo fatty acid of claim 1 that is 11-hydroxy-cis-7, cis-13,cis16,cis-19-docosatetraenoic acid.

6. The hydroxylated or oxo fatty acid of claim 1 that is 12-hydroxycis-5, cis-8, cis-14,cis-17-eicosatetraenoic acid.

7. The hydroxylated or oxo fatty acid of claim 1 that is 11-oxo-cis-4,cis-7,cis-13,cis-16,cis-19-docosapentaenoic acid.

8. The hydroxylated or oxo fatty acid of claim 1 that is 11-oxo-cis-7,cis-13,cis-16,cis-19-docosatetraenoic acid.

9. The hydroxylated or oxo fatty acid of claim 1 that is 12-oxo-cis5,cis-8,cis-14,cis-17-eicosatetraenoic acid.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE PROPERTY TYPE FROM APPLICATION NUMBER TO PATENT NUMBER FOR 10952983 AND 10975397 PREVIOUSLY RECORDED AT REEL: 68851 FRAME: 663. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 18, 2024
From: KYOTO UNIVERSITY
To: NOSTER INC.
Reel/Frame 069207/0122 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2024
From: KYOTO UNIVERSITY
To: NOSTER INC.
Reel/Frame 068851/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2021
From: OGAWA, JUN; KISHINO, SHIGENOBU; KITAO, KOHEY
To: KYOTO UNIVERSITY; NOSTER INC.
Reel/Frame 057645/0117 →
Priority Claims (1)
JP 2019-067966 · Mar 29, 2019 · national
Continuity (1)
Related Publication 20220042053A1 · Feb 10, 2022
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