IP Library Granted Patent US 12,405,146
Granted Patent B2
US 12,405,146 · App. 18/172,879 · Granted Sep 2, 2025

Replaceable, gamma sterilizable Coriolis flow sensors

Inventors: Deepak Bhagwan Malani (Boca Raton, FL); Jayasekar Rajagopalan (Cupertino, CA); Claus Waldersdorff Knudsen (Fremont, CA); Renato De Castro (Cupertino, CA)
Assignee: Malema Engineering Corporation
G01F1/8477
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,405,146
App. No.
18/172,879
Granted
Sep 2, 2025
Kind
B2
Abstract

A Coriolis flow sensor includes a metal flow tube and an enclosure. The enclosure encloses the flow tube and is constructed at least partially from a gamma transparent material. The metal flow tube may be constructed from stainless steel. The gamma transparent material and the flow tube are thin enough to permit sterilization of an interior of the flow tube by gamma irradiation of the flow tube through the gamma transparent material. The enclosure is also shaped to facilitate locking and unlocking the Coriolis flow sensor in place on a mounting structure.

Claims (36)

1. A process comprising:

obtaining a Coriolis mass flow sensor comprising at least one metal flow tube enclosed within an enclosure that is shaped to facilitate locking and unlocking the Coriolis flow sensor in place on a mounting structure, the enclosure constructed at least partially from a gamma transparent material, wherein the gamma transparent material and the metal flow tube are thin enough to permit sterilization of an interior of the metal flow tube by gamma irradiation of the metal flow tube through the gamma transparent material;

sterilizing the Coriolis mass flow sensor by using Gamma irradiation; and

storing calibration data for the Coriolis flow sensor in a gamma stable memory.

2. The process of claim 1 further comprising locking, by a locking mechanism, the Coriolis mass flow sensor in place on the mounting structure of a cradle, the cradle having a mass of at least ten (10) times a mass of the Coriolis mass flow sensor, wherein the locking mechanism produces sufficient locking force that the Coriolis flow sensor and the cradle vibrate as a unitary body.

3. The process of claim 2 further comprising unlocking the locking mechanism to release the Coriolis mass flow sensor.

4. The process of claim 2 , wherein the locking mechanism comprises thumb screws and tongues, the tongues arranged to overlap a ridge of the Coriolis mass flow sensor and, with the thumb screws tightened, press the ridge against an interior lip of a metal collar of the cradle.

5. The process of claim 2 , wherein the Coriolis flow sensor has a zero drift of not more than 1% of a minimum flow rate measured by the Coriolis flow sensor.

6. The process of claim 3 further comprising:

removing the Coriolis mass flow sensor from the cradle; and

replacing the Coriolis mass flow sensor with a different Coriolis mass flow sensor.

7. The process of claim 1 , wherein the at least one flow tube is constructed from stainless steel.

8. The process of claim 1 , wherein the gamma transparent material is plastic or polycarbonate.

9. The process of claim 1 , wherein the at least one flow tube is a U-tube, a V-tube, an -shaped tube, or a straight tube.

10. A Coriolis flow sensor comprising:

at least one metal flow tube enclosed within an enclosure that is shaped to facilitate locking and unlocking the Coriolis flow sensor in place on a mounting structure, the enclosure constructed at least partially from a gamma transparent material, wherein the gamma transparent material and the metal flow tube are thin enough to permit sterilization of an interior of the metal flow tube by gamma irradiation of the metal flow tube through the gamma transparent material.

11. The Coriolis flow sensor of claim 10 further comprising a gamma stable memory that stores calibration data for the Coriolis flow sensor.

12. The Coriolis flow sensor of claim 10 , wherein the Coriolis flow sensor has an accuracy of +/−1% of a flow rate over an operating range that has a turndown ratio of maximum flow rate to minimum flow rate of at least 200.

13. The Coriolis flow sensor of claim 10 , wherein the at least one flow tube is a metal flow tube.

14. The Coriolis flow sensor of claim 13 , where in the at least one metal flow tube is constructed from a stainless steel.

15. The Coriolis flow sensor of claim 10 further comprising:

a locking mechanism configured to lock the Coriolis flow sensor in place on the mounting structure of a cradle, the cradle having a mass of at least ten (10) times a mass of the Coriolis flow sensor, wherein the locking mechanism produces sufficient locking force that the Coriolis flow sensor and the cradle vibrate as a unitary body.

16. The Coriolis flow sensor of claim 15 , wherein the locking mechanism comprises thumb screws and tongues, the tongues arranged to overlap a ridge of the Coriolis flow sensor and, with the thumb screws tightened, press the ridge against an interior lip of a metal collar of the cradle.

17. The Coriolis flow sensor of claim 10 , wherein the at least one flow tube is a U-tube, a V-tube, an -shaped tube, or a straight tube.

18. The Coriolis flow sensor of claim 10 , wherein the Coriolis flow sensor is a disposable, single-use flow sensor.

19. A flow process system comprising:

a skid;

a cradle mounted on the skid, the cradle comprising a mounting structure;

a Coriolis flow sensor installed in the mounting structure, the Coriolis flow sensor comprising at least one metal flow tube enclosed within an enclosure that is shaped to facilitate locking and unlocking the Coriolis flow sensor in place on the mounting structure, the enclosure constructed at least partially from a gamma transparent material, wherein the gamma transparent material and the metal flow tube are thin enough to permit sterilization of an interior of the metal flow tube by gamma irradiation of the metal flow tube through the gamma transparent material; and

a locking mechanism that locks the Coriolis flow sensor in place on the mounting structure.

20. A flow process system comprising:

a skid;

a mixing manifold mounted on the skid;

a first flow path comprising a first pump and a first Coriolis flow sensor positioned along the first flow path and mounted on the skid, wherein the first pump and first Coriolis flow sensor are in fluid communication with a first inlet of the mixing manifold; and

a second flow path comprising a second pump and a second Coriolis flow sensor positioned along the second flow path and mounted on the skid, wherein the second pump and second Coriolis flow sensor are in fluid communication with a second inlet of the mixing manifold,

wherein each of the Coriolis flow sensors comprises at least one flow tube enclosed within an enclosure that is shaped to facilitate locking and unlocking the Coriolis flow sensor in place on a mounting structure, the enclosure constructed at least partially from a gamma transparent material, wherein the gamma transparent material and the flow tube are thin enough to permit sterilization of an interior of the flow tube by gamma irradiation of the flow tube through the gamma transparent material.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2023
From: MALANI, DEEPAK BHAGWAN; RAJAGOPALAN, JAYASEKAR; KNUDSEN, CLAUS WALDERSDORFF; CASTRO, RENATO DE
To: MALEMA ENGINEERING CORPORATION
Reel/Frame 062781/0302 →
Continuity (6)
Continuation 17718197 · Apr 11, 2022
Continuation In Part 17702554 · Mar 23, 2022
Continuation In Part 17523185 · Nov 10, 2021
Continuation 16846061 · Apr 10, 2020
Provisional Application 63274841 · Nov 2, 2021
Related Publication 20230243684A1 · Aug 3, 2023
References Cited (110)
US 3803912A · Ohno · 1974 [cited by applicant]
US 4252028A · Smith et al. · 1981 [cited by applicant]
US 4491025A · Smith et al. · 1985 [cited by applicant]
US 4768385A · Cage · 1988 [cited by applicant]
US 4823613A · Cage et al. · 1989 [cited by applicant]
US 4852409A · Herzl · 1989 [cited by applicant]
US 4934196A · Romano · 1990 [cited by applicant]
US 5038620A · Rogers et al. · 1991 [cited by applicant]
US 5343764A · Mattar et al. · 1994 [cited by applicant]
US 5373634A · Lipp · 1994 [cited by applicant]
US 5373745A · Caqe · 1994 [cited by applicant]
US 6156144A · Lueghamer · 2000 [cited by applicant]
US 6383423B1 · Kurokawa et al. · 2002 [cited by applicant]
US 6450042B1 · Lanham et al. · 2002 [cited by applicant]
US 6598488B1 · Sutton et al. · 2003 [cited by applicant]
US 6662120B2 · Drahm et al. · 2003 [cited by applicant]
US 6748813B1 · Barget et al. · 2004 [cited by applicant]
US 6776053B2 · Schlosser et al. · 2004 [cited by applicant]
US 6802224B2 · Nakao et al. · 2004 [cited by applicant]
US 6904667B2 · Lanham et al. · 2005 [cited by applicant]
US 7127815B2 · Schlosser et al. · 2006 [cited by applicant]
US 7350421B2 · Anklin-Imhof et al. · 2008 [cited by applicant]
US 7562585B2 · Schuetze et al. · 2009 [cited by applicant]
US 7716995B2 · Patten et al. · 2010 [cited by applicant]
US 8404076B2 · Young et al. · 2013 [cited by applicant]
US 8607643B2 · Wang et al. · 2013 [cited by applicant]
US 8887578B2 · Younq et al. · 2014 [cited by applicant]
US 9435695B2 · Mansfield · 2016 [cited by applicant]
US 9677921B2 · Young · 2017 [cited by applicant]
US 10209113B2 · Younq et al. · 2019 [cited by applicant]
US 10260922B2 · Young · 2019 [cited by applicant]
US 20020139199A1 · Lanham et al. · 2002 [cited by applicant]
US 20030097882A1 · Schlosser et al. · 2003 [cited by applicant]
US 20030191598A1 · Normen · 2003 [cited by applicant]
US 20050103122A1 · Dille · 2005 [cited by applicant]
US 20050252307A1 · Andresen et al. · 2005 [cited by applicant]
US 20060048897A1 · Temple · 2006 [cited by applicant]
US 20060201260A1 · Drahm et al. · 2006 [cited by applicant]
US 20070234824A1 · Bitto · 2007 [cited by examiner]
US 20090075129A1 · Sparks et al. · 2009 [cited by applicant]
US 20100251830A1 · Bitto et al. · 2010 [cited by applicant]
US 20100331644A1 · Neale et al. · 2010 [cited by applicant]
US 20110000315A1 · Tsubota et al. · 2011 [cited by applicant]
US 20110167910A1 · Storm et al. · 2011 [cited by applicant]
US 20110197650A1 · Young et al. · 2011 [cited by applicant]
US 20130042700A1 · Wang et al. · 2013 [cited by applicant]
US 20130086986A1 · Lanham et al. · 2013 [cited by applicant]
US 20130174670A1 · Young et al. · 2013 [cited by applicant]
US 20140060161A1 · Schick et al. · 2014 [cited by applicant]
US 20140174561A1 · Hagihara et al. · 2014 [cited by applicant]
US 20140188421A1 · Fraser et al. · 2014 [cited by applicant]
US 20150053021A1 · Young · 2015 [cited by applicant]
US 20150268082A1 · Kirst et al. · 2015 [cited by applicant]
US 20150300861A1 · Regen et al. · 2015 [cited by applicant]
US 20150377673A1 · Seeley et al. · 2015 [cited by applicant]
US 20170146380A1 · Young et al. · 2017 [cited by applicant]
US 20170176372A1 · Hanko · 2017 [cited by examiner]
US 20180179486A1 · Fadell et al. · 2018 [cited by applicant]
US 20190279888A1 · Gopalakrishnan et al. · 2019 [cited by applicant]
US 20200116612A1 · Ruetten et al. · 2020 [cited by applicant]
US 20200249071A1 · Cunningham et al. · 2020 [cited by applicant]
US 20200319006A1 · Malani et al. · 2020 [cited by applicant]
US 20210164826A1 · McAnally et al. · 2021 [cited by applicant]
US 20220236092A1 · Malani et al. · 2022 [cited by applicant]
CA 2590807C · 2012 [cited by applicant]
CN 87107806A · 1988 [cited by applicant]
CN 1426531A · 2003 [cited by applicant]
CN 1882800A · 2006 [cited by applicant]
CN 102782463A · 2012 [cited by applicant]
CN 206989514U · 2018 [cited by applicant]
DE 102019134605A1 · 2021 [cited by applicant]
EP 0190810A1 · 1986 [cited by applicant]
EP 0258827A1 · 1988 [cited by applicant]
EP 2100106B1 · 2011 [cited by applicant]
JP S6318219A · 1988 [cited by applicant]
JP H08052805A · 1996 [cited by applicant]
JP H09501493A · 1997 [cited by applicant]
JP H09057856A · 1997 [cited by applicant]
JP 2003525437A · 2003 [cited by applicant]
JP 2005510701A · 2005 [cited by applicant]
JP 2005510703A · 2005 [cited by applicant]
JP 2011058950A · 2011 [cited by applicant]
JP 2012025008A · 2012 [cited by applicant]
JP 2013519878A · 2013 [cited by applicant]
KR 101609734B1 · 2016 [cited by applicant]
TW 201518692A · 2015 [cited by applicant]
WO WO2017190823A1 · 2017 [cited by applicant]
U.S. Appl. No. 17/523,185, Malani et al. [cited by applicant]
Extended European Search Report in European Patent Application No. 14838532.1, dated Sep. 7, 2016, 9 pages. [cited by applicant]
Extended European Search Report in European Patent Application No. 21735838.1, dated Mar. 29, 2022, 9 pages. [cited by applicant]
First Office Action in Chinese Patent Application No. 201080063688.8, dated Apr. 4, 2014, 6 pages. [cited by applicant]
First Office Action in Chinese Patent Application No. 20140046308.8, dated Nov. 25, 2016, 22 pages. [cited by applicant]
International Search Report and Written Opinion in International Application No. PCT/US16/63398, mailed on Feb. 15, 2017, 14 pages. [cited by applicant]
International Search Report and Written Opinion in International Application No. PCT/US20/26258, mailed on Jun. 29, 2020, 17 pages. [cited by applicant]
International Search Report and Written Opinion in International Application No. PCT/US2014/051861, mailed on Dec. 22, 2014, 10 pages. [cited by applicant]
International Search Report and Written Opinion in International Appln. No. PCT/US2021/22497, mailed on Jun. 3, 2021, 11 pages. [cited by applicant]
JP Office Action in Japanese Patent Application No. 2016-536409, Sep. 26, 2017, 5 pages. [cited by applicant]
Kim et al., “Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials,” Nature, Feb. 27, 2018, 10 pages. [cited by applicant]
KR Office Action in Korean Patent Application No. 10-2012-7023722, dated Jan. 15, 2014, 10 pages. [cited by applicant]
Materials MDPI - On the potential of bulk metallic glasses for dental implantology: by Alethea liens et al. (Year: 2018). [cited by applicant]
Second Office Action in Chinese Patent Application No. 20140046308.8, dated Aug. 11, 2017, 8 pages. [cited by applicant]
The engineering toolbox - metals and alloys - Bulk modulus elasticity www.engineeringtoolbox.com (Year: 2008). [cited by applicant]
TW Office Action in Taiwanese Application No. 105138710, Aug. 2, 2017, 10 pages. [cited by applicant]
TW Office Action in Taiwanese Application No. 105138710, May 17, 2018, 10 pages. [cited by applicant]
TW Office Action in Taiwanese Patent Application No. 103129070, Jun. 10, 2015, 6 pages. [cited by applicant]
U.S. Office Action in U.S. Appl. No. 14/464,089, dated Feb. 26, 2016, 7 pages. [cited by applicant]
U.S. Office Action in U.S. Appl. No. 14/464,089, dated Sep. 9, 2016, 8 pages. [cited by applicant]
Extended European Search Report in European Appln. No. 23167175.1, dated Sep. 27, 2023, 11 pages. [cited by applicant]
Office Action in Korean Appln. No. 10-2023-0046747, mailed on May 27, 2024, 5 pages (with English translation). [cited by applicant]
Extended European Search Report in European Appln. No. 22890689.7, mailed on Jan. 20, 2025, 10 pages. [cited by applicant]