IP Library › Granted Patent US 12,414,798
Granted Patent B2
US 12,414,798 · App. 17/810,035 · Granted Sep 16, 2025

Systems and methods for delivering multiple ocular implants

Inventors: Charles Raymond Kalina, Jr. (Irvine, CA); Todd N. Fjield (Irvine, CA); Douglas Daniel Crimaldi (San Marcos, CA); Emma Claire Benjaminson (Laguna Hills, CA); Tyler Joseph Brown (Dana Point, CA); Richard William Martin (San Marcos, CA)
Assignee: Glaukos Corporation
A61B17/3468A61F9/0017A61F9/007A61F9/00781A61B2017/00367A61F2250/0064
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Quick Facts
Patent No.
US 12,414,798
App. No.
17/810,035
Granted
Sep 16, 2025
Kind
B2
Abstract

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include a plurality of implants, an external housing, and an introducer assembly. The external housing can provide access to an implant singulation actuator and an implant delivery actuator. The introducer assembly can comprise an auto-retracting introducer portion. The delivery apparatus can include an infinite activation mechanism/portion and/or a manual singulation mechanism/portion.

Claims (27)

1. An implant delivery apparatus configured to deliver a plurality of implants for treating an ocular disorder, the apparatus comprising:

an external housing comprising an opening on an upper side of the external housing;

an auto-retracting introducer assembly configured to facilitate introduction of a distal portion of the implant delivery apparatus into an eye of a subject, the introducer assembly comprising a distal introducer tip and a flexible proximal retraction member extending from a distal end of the external housing;

a singulation assembly configured to facilitate on-demand singulation of each of the plurality of implants upon manual actuation by an operator of a lever extending out of the opening of the external housing; and

an implantation actuator assembly configured to effect delivery of each of the plurality of implants following singulation, the implantation actuator assembly comprising an implant delivery actuator comprising a trigger button extending out of the opening of the external housing that is configured to be actuated a plurality of times by the operator.

2. The apparatus of claim 1 , further comprising an insertion tube extending from a distal end of the external housing at an angle relative to a longitudinal axis of the implant delivery apparatus, the insertion tube configured to retain the plurality of implants therein.

3. The apparatus of claim 1 , further comprising a collet holder assembly comprising a collet holder and a singulation tube extending from the collet holder, wherein a distal end of the singulation tube comprises multiple tines configured to facilitate retraction of the distal end of the singulation tube over a maximum cross-sectional dimension of a respective implant during singulation, and wherein the distal end of the singulation tube is configured to engage a proximal end of the respective implant following singulation and advance the respective implant to a ready-to-fire position.

4. The apparatus of claim 3 , wherein the singulation assembly further comprises a singulation arm coupled to the lever and to the collet holder and a singulation biasing member coupled to the singulation arm and to a fixed frame within the external housing, wherein proximal retraction of the lever of the singulation assembly causes the collet holder to retract proximally and such that release of the lever causes the singulation tube to engage the proximal end of the respective implant following singulation and advance the respective implant to the ready-to-fire position.

5. The apparatus of claim 4 , wherein the implantation actuator assembly further comprises an actuator arm and an actuator biasing member, wherein the energy sufficient to effect delivery of each respective implant is provided by the actuator biasing member, and wherein the energy provided by the actuator biasing member is generated from pressing of the trigger button of the implant delivery actuator by the operator.

6. The apparatus of claim 4 , wherein the frame comprises a singulation frame slot comprising a plurality of platforms sized and shaped to facilitate singulation of the plurality of implants.

7. The apparatus of claim 5 , wherein the actuator biasing member comprises a flat spring.

8. The implant delivery apparatus of claim 7 , wherein depressing of the trigger button causes the flat spring to bend, thereby storing the energy.

9. The implant delivery apparatus of claim 7 , wherein the flat spring is positioned in contact with the actuator arm so as to cause the flat spring to bend as the trigger button is depressed.

10. The apparatus of claim 4 , wherein the singulation biasing member comprises a spring.

11. An implant delivery apparatus configured to deliver a plurality of implants for treating an ocular disorder, the apparatus comprising:

an external housing comprising an opening on an upper side of the external housing;

a singulation assembly configured to facilitate on-demand singulation of each of the plurality of implants upon manual actuation by an operator of a lever extending out of the opening of the external housing; and

an implantation actuator assembly configured to effect delivery of each of the plurality of implants following singulation, the implantation actuator assembly comprising an implant delivery actuator comprising a trigger button extending out of the opening of the external housing that is configured to be actuated a plurality of times by the operator.

12. The apparatus of claim 11 , further comprising a collet holder assembly comprising a collet holder and a singulation tube extending from the collet holder, wherein a distal end of the singulation tube comprises multiple tines configured to facilitate retraction of the distal end of the singulation tube over a maximum cross-sectional dimension of a respective implant during singulation, and wherein the distal end of the singulation tube is configured to engage a proximal end of the respective implant following singulation and advance the respective implant to a ready-to-fire position.

13. The apparatus of claim 12 , wherein the singulation assembly further comprises a singulation arm coupled to the lever and to the collet holder and a singulation biasing member coupled to the singulation arm and to a fixed frame within the external housing, wherein proximal retraction of the lever of the singulation assembly causes the collet holder to retract proximally and such that release of the lever causes the singulation tube to engage the proximal end of the respective implant following singulation and advance the respective implant to the ready-to-fire position.

14. The apparatus of claim 13 , wherein the implantation actuator assembly further comprises an actuator arm and an actuator biasing member, wherein the energy sufficient to effect delivery of each respective implant is provided by the actuator biasing member, and wherein the energy provided by the actuator biasing member is generated from pressing of the trigger button of the implant delivery actuator by the operator.

15. The apparatus of claim 14 , wherein the actuator biasing member comprises a flat spring.

16. The implant delivery apparatus of claim 15 , wherein depressing of the trigger button causes the flat spring to bend, thereby storing the energy.

17. The implant delivery apparatus of claim 15 , wherein the flat spring is positioned in contact with the actuator arm so as to cause the flat spring to bend as the trigger button is depressed.

18. The apparatus of claim 13 , wherein the frame comprises a singulation frame slot comprising a plurality of platforms sized and shaped to facilitate singulation of the plurality of implants.

19. The apparatus of claim 13 , wherein the singulation biasing member comprises a spring.

20. The apparatus of claim 11 , further comprising an insertion tube extending from a distal end of the external housing at an angle relative to a longitudinal axis of the implant delivery apparatus, the insertion tube configured to retain the plurality of implants therein.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2022
From: KALINA, CHARLES RAYMOND, JR; FJIELD, TODD N.; CRIMALDI, DOUGLAS DANIEL; BENJAMINSON, EMMA CLAIRE; BROWN, TYLER JOSEPH; MARTIN, RICHARD WILLIAM
To: GLAUKOS CORPORATION
Reel/Frame 060564/0462 →
Continuity (5)
Division 16132252 · Sep 14, 2018
Provisional Application 62671286 · May 14, 2018
Provisional Application 62578273 · Oct 27, 2017
Provisional Application 62569458 · Oct 6, 2017
Related Publication 20220330979A1 · Oct 20, 2022
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