IP Library › Granted Patent US 12,415,145
Granted Patent B2
US 12,415,145 · App. 18/410,366 · Granted Sep 16, 2025

Compositions that contain lipophilic plant material and surfactant, and related methods

Inventor: Michael V. Zumpano (Fairfield, CA)
B01D11/0288A61K36/185B01D9/0036B01D11/0257B01D11/0265B01D11/028B01D11/0292B01D11/0492
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Quick Facts
Patent No.
US 12,415,145
App. No.
18/410,366
Granted
Sep 16, 2025
Kind
B2
Abstract

Described are liquid compositions that contain a desired (e.g., extracted) plant material such as cannabinoid, terpene, terpenoid, or the like, contained, e.g., dissolved, suspended, or emulsified, in the liquid, which contains surfactant; methods of preparing these types of liquid compositions; and methods of processing this type of liquid composition to collect, isolate, concentrate, or purify a desired target material contained in the liquid composition.

Claims (36)

1. A plant extract composition comprising:

at least 15 weight percent surfactant, and

at least 5 weight percent plant material, based on total weight of the plant extract composition; wherein the surfactant comprises each of:

a pH-dependent surfactant comprising alkylamine alkoxylate surfactant, and

an amide-based surfactant having the formula R4C(O) NR5R6, wherein R4, RS, and R6 are independently selected from saturated and unsaturated hydrocarbon-containing groups.

2. The plant extract composition of claim 1 comprising:

from 15 to 70 weight percent surfactant, and

at least 20 weight percent extracted lipophilic plant material that is dissolved, suspended, or emulsified within the plant extract composition, based on total weight of the plant extract composition.

3. The plant extract composition of claim 2 comprising:

less than 5 weight percent oil different from oil in the extracted lipophilic plant material, based on total weight of the plant extract composition, cannabinoid plant material, based on total weight plant extract composition.

4. The plant extract composition of claim 1 comprising at least 5 weight percent cannabinoid plant material, based on total weight of the plant extract composition.

5. The plant extract composition of claim 1 comprising not more than 20 weight percent water based on total weight of the plant extract composition.

6. The plant extract composition of claim 1 wherein R4, R5, and R6 combined have a total number of carbon atoms in the range from 6-16.

7. The plant extract composition of claim 1 comprising:

from 0.1 to 40 weight percent pH-dependent surfactant, and

from 1 to 20 weight percent amide-based surfactant, based on total weight of the plant extract composition.

8. A method of extracting material from solid plant material, the method comprising:

contacting solid plant material with liquid extraction medium comprising water, surfactant, and base, the surfactant comprising at least 0.1 weight percent pH-dependent surfactant based on total weight of the liquid extraction medium, and the liquid extraction medium having a basic pH; and

after contacting the solid plant material with liquid extraction medium, lowering the pH of the liquid extraction medium to cause an emulsion of the liquid extraction medium to de-emulsify and form multiple phases, including an aqueous phase and a non-aqueous phase.

9. The method of claim 8 wherein the non-aqueous phase comprises:

at least 15 weight percent surfactant,

at least 1 weight percent cannabinoid, and

not more than 20 weight percent water, based on total weight of the non-aqueous phase.

10. The method of claim 8 comprising:

after lowering the pH of the liquid extraction medium, processing the liquid extraction medium to form a plant extract composition comprising:

at least 15 weight percent surfactant,

at least 1 weight percent cannabinoid, and

not more than 20 weight percent water, based on total weight of the non-aqueous phase; and

separating the cannabinoid from the plant extract composition by forming a liquid or solid phase that contains a concentrated amount of the cannabinoid.

11. A method for extracting a lipophilic plant material from a plant, comprising steps of:

a) obtaining a plant or portion thereof comprising a lipophilic plant material;

b) processing the plant or portion thereof in an aqueous composition, wherein the aqueous composition has a basic pH and comprises at least one surfactant;

c) lowering the pH of the aqueous composition wherein the at least one surfactant: i) partially or fully loses its ability to emulsify lipophilic and hydrophilic components in the processed plant aqueous composition, or ii) partially or fully disassociates with from the lipophilic plant material, or iii) is chemically cleaved into two or more surfactant by-products, or any combination of two or more of 1)-iii); and

d) partially or fully separating the at least one surfactant from the lipophilic plant material.

12. The method of claim 11 , where, in step b): the pH of the aqueous composition in step b) is greater than about 9.

13. The method of claim 11 , wherein the at least one surfactant comprises a non-ionic surfactant.

Continuity (5)
Continuation 17459599 · Aug 27, 2021
Continuation PCTUS2020020235 · Feb 27, 2020
Provisional Application 62849563 · May 17, 2019
Provisional Application 62811427 · Feb 27, 2019
Related Publication 20240189739A1 · Jun 13, 2024
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