IP Library › Granted Patent US 12,416,798
Granted Patent B2
US 12,416,798 · App. 18/614,393 · Granted Sep 16, 2025

Systems and methods for medical imaging

Inventors: Hossein Dehghani (Boston, MA); Vasiliy E. Buharin (Boston, MA); Roman Stolyarov (Boston, MA); Thomas Calef (Boston, MA); Liam O'Shea (Boston, MA); Alexander J. Dye (Boston, MA); Chris J. Situ (Boston, MA)
Assignee: ACTIV Surgical, Inc.
G02B23/2423A61B1/06H04N23/45H04N23/55H04N23/58
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Quick Facts
Patent No.
US 12,416,798
App. No.
18/614,393
Granted
Sep 16, 2025
Kind
B2
Abstract

The present disclosure provides systems and methods for medical imaging. The system may comprise a scope assembly. The scope assembly may comprise a housing unit configured to releasably couple to at least a portion of an elongated scope. The scope assembly may comprise an imaging unit operably coupled to the housing unit, wherein the imaging unit comprises an optics assembly configured to (i) receive one or more light beams that are transmitted through the elongated scope and (ii) direct at least a portion of the one or more light beams onto two or more locations within a subject's body. At least one of the two or more locations may comprise a target site. The imaging unit may be configured to move via a rotational and/or translational motion relative to the housing unit to alter a field of view when imaging within the subject's body.

Claims (35)

1. A scope assembly, comprising:

an elongated scope;

an imaging unit operably coupled to a distal tip of the elongated scope, wherein the imaging unit is configured to move relative to the elongated scope and obtain a plurality of imaging data of a target site from a plurality of perspectives using at least two imaging sensors having different optical axes;

one or more motion sensors within the imaging unit, wherein the one or more motion sensors are configured to provide spatial information of the imaging unit as the imaging unit moves relative to the elongated scope; and

a processor operatively coupled to the imaging unit and the sensors, wherein the processor is configured to generate a three-dimensional (3D) reconstruction of the target site based on the plurality of imaging data and the spatial information.

2. The scope assembly of claim 1 , wherein the one or more motion sensors are configured to sense one of position, orientation, or acceleration of at least a portion of the scope assembly.

3. The scope assembly of claim 1 wherein the one or more motion sensors comprise:

a first motion sensor configured to detect and record one of position, orientation, or acceleration of an imaging unit arm coupled to the imaging unit; and

a second motion sensor configured to detect and record one of position, orientation, or acceleration of the imaging unit.

4. The scope assembly of claim 1 , wherein the one or more motion sensors comprise an inertial measurement unit.

5. The scope assembly of claim 1 , wherein the one or more motion sensors are further configured to provide spatiotemporal information of the imaging unit.

6. The scope assembly of claim 1 , wherein the one or more motion sensors are further configured to measure movement of the imaging unit relative to at least a portion of the elongated scope.

7. The scope assembly of claim 6 , wherein the measured movement comprises spatiotemporal movement of the imaging unit.

8. The scope assembly of claim 6 , wherein the measured movement is combined with the imaging data to produce the 3D reconstruction of the target site.

9. The scope assembly of claim 1 , wherein the imaging unit is configured to move relative to the elongated scope via one or more joint mechanisms, and wherein the one or more motion sensors are operatively coupled to the one or more joint mechanisms.

10. The scope assembly of claim 9 , wherein the imaging unit comprises a plurality of joint mechanisms, and wherein an individual joint mechanism of the plurality of joint mechanisms comprises at least one motion sensor.

11. A method comprising:

providing a scope assembly including (i) an elongated scope, (ii) an imaging unit operatively coupled to a distal tip of the elongated scope, and (iii) one or more motion sensors operatively coupled to the imaging unit;

moving the imaging unit relative to the elongated scope to obtain a plurality of imaging data of a target site from a plurality of perspectives using at least two imaging sensors having different optical axes;

providing spatial information of the imaging unit using the motion sensors within the imaging unit as the imaging unit moves relative to the elongated scope; and

generating a three-dimensional (3D) reconstruction of the target site using a processor based on the plurality of imaging data and the spatial information.

12. The method of claim 11 , wherein providing the spatial information further comprises:

sensing one of position, orientation, or acceleration of the imaging unit.

13. The method of claim 11 , wherein the one or more motion sensors comprise an inertial measurement unit.

14. The method of claim 11 , wherein providing the spatial information further comprises providing the spatial information using spatiotemporal information of the imaging unit.

15. The method of claim 11 wherein providing the spatial information further comprises measuring movement of the imaging unit relative to at least a portion of the elongated scope.

16. The method of claim 15 wherein the measured movement comprises spatiotemporal movement of the imaging unit.

17. The method of claim 15 wherein generating the 3D reconstruction of the target site further comprises combining the measured movement with the imaging data to produce the 3D reconstruction of the target site.

18. The method of claim 11 , wherein moving the imaging unit relative to the elongated scope further comprises moving the imaging unit via one or more joint mechanisms.

19. The method of claim 18 , wherein the one or more joint mechanisms includes a plurality of joint mechanisms at least one of which has a motion sensor.

20. A scope assembly, comprising:

an elongated scope;

an imaging unit operably coupled to a distal tip of the elongated scope, wherein the imaging unit is configured to (i) move relative to the elongated scope via one or more joint mechanisms and (ii) obtain a plurality of imaging data of a target site from a plurality of perspectives using at least two imaging sensors having different optical axes;

one or more motion sensors within the imaging unit and the joint mechanisms, wherein the one or more motion sensors are configured to provide spatiotemporal information of the imaging unit as the imaging unit moves relative to the elongated scope; and

a processor operatively coupled to the imaging unit and the sensors, wherein the processor is configured to generate a three-dimensional (3D) reconstruction of the target site based on the plurality of imaging data and the spatiotemporal information.

Continuity (6)
Continuation 17673324 · Feb 16, 2022
Continuation PCTUS2020047275 · Aug 20, 2020
Provisional Application 62889863 · Aug 21, 2019
Provisional Application 62953724 · Dec 26, 2019
Provisional Application 62960897 · Jan 14, 2020
Related Publication 20240353669A1 · Oct 24, 2024
References Cited (400)
US 4349014A · Takamatsu · 1982 [cited by applicant]
US 4576456A · Okino · 1986 [cited by applicant]
US 4592632A · Renold · 1986 [cited by applicant]
US 4844071A · Chen et al. · 1989 [cited by applicant]
US 4974076A · Nakamura · 1990 [cited by applicant]
US 5748930A · Prakash · 1998 [cited by applicant]
US 5749830A · Kaneko · 1998 [cited by applicant]
US 5980450A · Thompson · 1999 [cited by applicant]
US 6069698A · Ozawa et al. · 2000 [cited by applicant]
US 6088105A · Link · 2000 [cited by applicant]
US 6373963B1 · Demers et al. · 2002 [cited by applicant]
US 6438302B1 · Utsui · 2002 [cited by applicant]
US 6491702B2 · Heilbrun et al. · 2002 [cited by applicant]
US 6503195B1 · Keller et al. · 2003 [cited by applicant]
US 6537211B1 · Wang · 2003 [cited by applicant]
US 6542249B1 · Kofman et al. · 2003 [cited by applicant]
US 6549288B1 · Migdal et al. · 2003 [cited by applicant]
US 6563105B2 · Seibel et al. · 2003 [cited by applicant]
US 6564086B2 · Marchitto et al. · 2003 [cited by applicant]
US 6613041B1 · Schrunder · 2003 [cited by applicant]
US 6635011B1 · Ozawa · 2003 [cited by applicant]
US 6697164B1 · Babayoff et al. · 2004 [cited by applicant]
US 6800057B2 · Tsujita et al. · 2004 [cited by applicant]
US 6850872B1 · Marschner et al. · 2005 [cited by applicant]
US 6873867B2 · Vilsmeier · 2005 [cited by applicant]
US 6885464B1 · Pfeiffer et al. · 2005 [cited by applicant]
US RE38800E · Barbour · 2005 [cited by applicant]
US 6965690B2 · Matsumoto · 2005 [cited by applicant]
US 6977732B2 · Chen et al. · 2005 [cited by applicant]
US 6987531B2 · Kamon · 2006 [cited by applicant]
US 7006236B2 · Tomasi et al. · 2006 [cited by applicant]
US 7068825B2 · Rubbert et al. · 2006 [cited by applicant]
US 7092107B2 · Babayoff et al. · 2006 [cited by applicant]
US 7099732B2 · Geng · 2006 [cited by applicant]
US 7124066B2 · Marschner et al. · 2006 [cited by applicant]
US 7152024B2 · Marschner et al. · 2006 [cited by applicant]
US 7184150B2 · Quadling et al. · 2007 [cited by applicant]
US 7200262B2 · Sawada · 2007 [cited by applicant]
US 7224384B1 · Iddan et al. · 2007 [cited by applicant]
US 7230725B2 · Babayoff et al. · 2007 [cited by applicant]
US 7242997B2 · Geng · 2007 [cited by applicant]
US 7305110B2 · Rubbert et al. · 2007 [cited by applicant]
US 7313264B2 · Crampton · 2007 [cited by applicant]
US 7319529B2 · Babayoff · 2008 [cited by applicant]
US 7363201B2 · Marschner et al. · 2008 [cited by applicant]
US 7385708B2 · Ackerman et al. · 2008 [cited by applicant]
US 7433807B2 · Marschner et al. · 2008 [cited by applicant]
US 7435217B2 · Wiklof · 2008 [cited by applicant]
US 7450783B2 · Talapov et al. · 2008 [cited by applicant]
US 7477402B2 · Babayoff et al. · 2009 [cited by applicant]
US 7489408B2 · Harding et al. · 2009 [cited by applicant]
US 7491956B2 · Knoche et al. · 2009 [cited by applicant]
US 7492927B2 · Marschner et al. · 2009 [cited by applicant]
US 7511829B2 · Babayoff · 2009 [cited by applicant]
US 7522764B2 · Schwotzer · 2009 [cited by applicant]
US 7577299B2 · Kawamata et al. · 2009 [cited by applicant]
US 7620209B2 · Stevick et al. · 2009 [cited by applicant]
US 7630089B2 · Babayoff et al. · 2009 [cited by applicant]
US 7704206B2 · Suzuki et al. · 2010 [cited by applicant]
US 7724378B2 · Babayoff · 2010 [cited by applicant]
US 7724932B2 · Ernst et al. · 2010 [cited by applicant]
US 7751871B2 · Rubbert · 2010 [cited by applicant]
US 7763841B1 · McEldowney · 2010 [cited by applicant]
US 7794388B2 · Draxinger et al. · 2010 [cited by applicant]
US 7821649B2 · Bendall et al. · 2010 [cited by applicant]
US 7854700B2 · Orihara · 2010 [cited by applicant]
US 7898651B2 · Hu et al. · 2011 [cited by applicant]
US 7944569B2 · Babayoff et al. · 2011 [cited by applicant]
US 7951073B2 · Freed · 2011 [cited by applicant]
US 7961912B2 · Stevick et al. · 2011 [cited by applicant]
US 7967743B2 · Ishihara · 2011 [cited by applicant]
US 7990548B2 · Babayoff et al. · 2011 [cited by applicant]
US 7995798B2 · Krupnik et al. · 2011 [cited by applicant]
US 8027710B1 · Dannan · 2011 [cited by applicant]
US 8038609B2 · Kohno et al. · 2011 [cited by applicant]
US 8084753B2 · Joshi et al. · 2011 [cited by applicant]
US 8194122B2 · Amling et al. · 2012 [cited by applicant]
US 8264536B2 · McEldowney · 2012 [cited by applicant]
US 8279418B2 · Yee et al. · 2012 [cited by applicant]
US 8280152B2 · Thiel et al. · 2012 [cited by applicant]
US 8310683B2 · Babayoff et al. · 2012 [cited by applicant]
US 8320621B2 · McEldowney · 2012 [cited by applicant]
US 8326020B2 · Lee et al. · 2012 [cited by applicant]
US 8330804B2 · Lutian et al. · 2012 [cited by applicant]
US 8400494B2 · Zalevsky et al. · 2013 [cited by applicant]
US 8406859B2 · Zuzak et al. · 2013 [cited by applicant]
US 8471897B2 · Rodriguez Ramos et al. · 2013 [cited by applicant]
US 8517928B2 · Orihara · 2013 [cited by applicant]
US 8553939B2 · Craig et al. · 2013 [cited by applicant]
US 8558873B2 · McEldowney · 2013 [cited by applicant]
US 8593507B2 · Yahav · 2013 [cited by applicant]
US 8610665B2 · Craig et al. · 2013 [cited by applicant]
US 8649024B2 · Colonna De Lega · 2014 [cited by applicant]
US 8659765B2 · Ando · 2014 [cited by applicant]
US 8723118B2 · McEldowney et al. · 2014 [cited by applicant]
US 8723923B2 · Bloom et al. · 2014 [cited by applicant]
US 8755053B2 · Fright et al. · 2014 [cited by applicant]
US 8792098B2 · Dewald et al. · 2014 [cited by applicant]
US 8803952B2 · Katz et al. · 2014 [cited by applicant]
US 8823790B2 · Dunn et al. · 2014 [cited by applicant]
US 8891087B2 · Zuzak et al. · 2014 [cited by applicant]
US 8896594B2 · Xiong et al. · 2014 [cited by applicant]
US 8974378B2 · Imaizumi et al. · 2015 [cited by applicant]
US 9001190B2 · Olivier, III et al. · 2015 [cited by applicant]
US 9057784B2 · Hudman · 2015 [cited by applicant]
US 9068824B2 · Findeisen et al. · 2015 [cited by applicant]
US 9070194B2 · Lee et al. · 2015 [cited by applicant]
US 9072445B2 · Berguer et al. · 2015 [cited by applicant]
US 9074868B2 · Bendall et al. · 2015 [cited by applicant]
US 9089277B2 · Babayoff et al. · 2015 [cited by applicant]
US 9119552B2 · Baumann et al. · 2015 [cited by applicant]
US 9135502B2 · Haker et al. · 2015 [cited by applicant]
US 9142025B2 · Park et al. · 2015 [cited by applicant]
US 9147253B2 · Yee et al. · 2015 [cited by applicant]
US 9149348B2 · Wu et al. · 2015 [cited by applicant]
US 9155480B2 · Thakor et al. · 2015 [cited by applicant]
US 9157728B2 · Ogawa · 2015 [cited by applicant]
US 9157733B2 · Dillon et al. · 2015 [cited by applicant]
US 9198578B2 · Zuzak et al. · 2015 [cited by applicant]
US 9204952B2 · Lampalzer · 2015 [cited by applicant]
US 9220570B2 · Kim et al. · 2015 [cited by applicant]
US 9226645B2 · Ntziachristos · 2016 [cited by applicant]
US 9226673B2 · Ferguson, Jr. et al. · 2016 [cited by applicant]
US 9247865B2 · Igarashi et al. · 2016 [cited by applicant]
US 9254076B2 · McDowall · 2016 [cited by applicant]
US 9254078B2 · McDowall · 2016 [cited by applicant]
US 9254103B2 · Krishnaswamy et al. · 2016 [cited by applicant]
US 9261356B2 · Lampert et al. · 2016 [cited by applicant]
US 9261358B2 · Atiya et al. · 2016 [cited by applicant]
US 9271633B2 · Scott et al. · 2016 [cited by applicant]
US 9271658B2 · Ferguson, Jr. et al. · 2016 [cited by applicant]
US 9274047B2 · Velten et al. · 2016 [cited by applicant]
US 9282926B2 · Schwotzer et al. · 2016 [cited by applicant]
US 9294758B2 · Xiong et al. · 2016 [cited by applicant]
US 9297889B2 · Hudman et al. · 2016 [cited by applicant]
US 9304603B2 · Miller · 2016 [cited by applicant]
US 9330464B1 · Ackerman et al. · 2016 [cited by applicant]
US 9345389B2 · Nie et al. · 2016 [cited by applicant]
US 9345392B2 · Saito · 2016 [cited by applicant]
US 9345397B2 · Taylor et al. · 2016 [cited by applicant]
US 9351643B2 · Sharonov · 2016 [cited by applicant]
US 9364300B2 · Tchouprakov et al. · 2016 [cited by applicant]
US 9375844B2 · Itkowitz et al. · 2016 [cited by applicant]
US 9377295B2 · Fright et al. · 2016 [cited by applicant]
US 9380224B2 · Keskin et al. · 2016 [cited by applicant]
US 9389068B2 · Ri · 2016 [cited by applicant]
US 9404741B2 · Schick · 2016 [cited by applicant]
US 9432593B2 · Yang et al. · 2016 [cited by applicant]
US 9439568B2 · Atiya et al. · 2016 [cited by applicant]
US 9443310B2 · Hudman et al. · 2016 [cited by applicant]
US 9444981B2 · Bellis et al. · 2016 [cited by applicant]
US 9451872B2 · Yokota · 2016 [cited by applicant]
US 9462253B2 · Hudman et al. · 2016 [cited by applicant]
US 9471864B2 · Zatloukal et al. · 2016 [cited by applicant]
US 9491441B2 · Sarmast et al. · 2016 [cited by applicant]
US 9494418B2 · Schmidt · 2016 [cited by applicant]
US 9506749B2 · Bellis et al. · 2016 [cited by applicant]
US 9513113B2 · Yang et al. · 2016 [cited by applicant]
US 9513768B2 · Zhao et al. · 2016 [cited by applicant]
US 9545220B2 · Sidlesky · 2017 [cited by applicant]
US 9554692B2 · Levy · 2017 [cited by applicant]
US 9557574B2 · McEldowney · 2017 [cited by applicant]
US 9581802B2 · Yokota · 2017 [cited by applicant]
US 9615901B2 · Babayoff et al. · 2017 [cited by applicant]
US 9622644B2 · Yokota · 2017 [cited by applicant]
US 9622662B2 · Zuzak et al. · 2017 [cited by applicant]
US 9638801B2 · Boufounos et al. · 2017 [cited by applicant]
US 9674436B2 · Crane et al. · 2017 [cited by applicant]
US 9675429B2 · Lampert et al. · 2017 [cited by applicant]
US 9690984B2 · Butler et al. · 2017 [cited by applicant]
US 9696427B2 · Wilson et al. · 2017 [cited by applicant]
US 9720506B2 · Kim et al. · 2017 [cited by applicant]
US 9729860B2 · Cohen et al. · 2017 [cited by applicant]
US 9737239B2 · Kimmel · 2017 [cited by applicant]
US 9739594B2 · Koerner et al. · 2017 [cited by applicant]
US 9746318B2 · Sugano · 2017 [cited by applicant]
US 9752867B2 · Atiya et al. · 2017 [cited by applicant]
US 9782056B2 · McDowall · 2017 [cited by applicant]
US 9788903B2 · Kim et al. · 2017 [cited by applicant]
US 9799117B2 · Chen et al. · 2017 [cited by applicant]
US 9817159B2 · Hudman · 2017 [cited by applicant]
US 9833145B2 · Jeong et al. · 2017 [cited by applicant]
US 9841496B2 · Hudman · 2017 [cited by applicant]
US 9844427B2 · Atiya et al. · 2017 [cited by applicant]
US 9901409B2 · Yang et al. · 2018 [cited by applicant]
US 9918640B2 · Ntziachristos et al. · 2018 [cited by applicant]
US 9922249B2 · Kang et al. · 2018 [cited by applicant]
US 9939258B2 · Lampert et al. · 2018 [cited by applicant]
US 9943271B2 · Dirauf et al. · 2018 [cited by applicant]
US 9947099B2 · Bleyer et al. · 2018 [cited by applicant]
US 9953428B2 · Gren et al. · 2018 [cited by applicant]
US 9955140B2 · Rhemann et al. · 2018 [cited by applicant]
US 9955861B2 · Gao et al. · 2018 [cited by applicant]
US 9958585B2 · Powell et al. · 2018 [cited by applicant]
US 9958758B2 · Hudman · 2018 [cited by applicant]
US 9962244B2 · Esbech et al. · 2018 [cited by applicant]
US 9970753B2 · Han et al. · 2018 [cited by applicant]
US 10011014B2 · Divoky et al. · 2018 [cited by applicant]
US 10018464B2 · Boles et al. · 2018 [cited by applicant]
US 10024968B2 · Hudman et al. · 2018 [cited by applicant]
US 10039439B2 · Aoyama · 2018 [cited by applicant]
US 10045882B2 · Balicki et al. · 2018 [cited by applicant]
US 10055856B2 · Sabater et al. · 2018 [cited by applicant]
US 10058256B2 · Chen et al. · 2018 [cited by applicant]
US 10066997B2 · Korner et al. · 2018 [cited by applicant]
US 10089737B2 · Krieger et al. · 2018 [cited by applicant]
US 10169862B2 · Andre et al. · 2019 [cited by applicant]
US 10244991B2 · Shademan et al. · 2019 [cited by applicant]
US 10390718B2 · Chen et al. · 2019 [cited by applicant]
US 10398519B2 · Kim et al. · 2019 [cited by applicant]
US 10575737B2 · Andre et al. · 2020 [cited by applicant]
US 10675040B2 · Kim et al. · 2020 [cited by applicant]
US 10681259B2 · Ichiki et al. · 2020 [cited by applicant]
US 10694117B2 · Frangioni · 2020 [cited by applicant]
US 10722173B2 · Chen et al. · 2020 [cited by applicant]
US 10792492B2 · Chen et al. · 2020 [cited by applicant]
US 10925465B2 · Tully et al. · 2021 [cited by applicant]
US 10948350B2 · Ferguson, Jr. et al. · 2021 [cited by applicant]
US 10966597B2 · Yamazoe et al. · 2021 [cited by applicant]
US 11135028B2 · Kim et al. · 2021 [cited by applicant]
US 11278220B2 · Tucker et al. · 2022 [cited by applicant]
US 11389051B2 · Tully et al. · 2022 [cited by applicant]
US 11754828B2 · Tully et al. · 2023 [cited by applicant]
US 11977218B2 · Dehghani et al. · 2024 [cited by applicant]
US 20010030983A1 · Yuri et al. · 2001 [cited by applicant]
US 20020021355A1 · Utsui · 2002 [cited by applicant]
US 20020022768A1 · Utsui · 2002 [cited by applicant]
US 20030050532A1 · Doguchi · 2003 [cited by applicant]
US 20030176768A1 · Gono · 2003 [cited by applicant]
US 20030195623A1 · Marchitto et al. · 2003 [cited by applicant]
US 20040257438A1 · Doguchi · 2004 [cited by applicant]
US 20050010084A1 · Tsai · 2005 [cited by applicant]
US 20050096515A1 · Geng · 2005 [cited by applicant]
US 20050220447A1 · Ito · 2005 [cited by applicant]
US 20050267329A1 · Konstorum et al. · 2005 [cited by applicant]
US 20060173240A1 · Fukuyama · 2006 [cited by applicant]
US 20070055103A1 · Hoefig et al. · 2007 [cited by applicant]
US 20070115484A1 · Huang et al. · 2007 [cited by applicant]
US 20070146719A1 · Wedel · 2007 [cited by applicant]
US 20070165243A1 · Kang et al. · 2007 [cited by applicant]
US 20070276185A1 · Gono · 2007 [cited by applicant]
US 20070280423A1 · Schmidt · 2007 [cited by applicant]
US 20080107305A1 · Vanderkooy et al. · 2008 [cited by applicant]
US 20080218826A1 · DeSaulniers · 2008 [cited by applicant]
US 20080266391A1 · Lee et al. · 2008 [cited by applicant]
US 20090216085A1 · Yamazaki · 2009 [cited by applicant]
US 20090221874A1 · Vinther et al. · 2009 [cited by applicant]
US 20090244260A1 · Takahashi et al. · 2009 [cited by applicant]
US 20090289200A1 · Ishii · 2009 [cited by applicant]
US 20100097454A1 · Kubo · 2010 [cited by applicant]
US 20100113921A1 · Fear et al. · 2010 [cited by applicant]
US 20100210904A1 · Cline et al. · 2010 [cited by applicant]
US 20110015518A1 · Schmidt et al. · 2011 [cited by applicant]
US 20110043609A1 · Choi et al. · 2011 [cited by applicant]
US 20110057930A1 · Keller et al. · 2011 [cited by applicant]
US 20110069162A1 · Ozawa et al. · 2011 [cited by applicant]
US 20110071352A1 · Ozawa et al. · 2011 [cited by applicant]
US 20110080471A1 · Song et al. · 2011 [cited by applicant]
US 20110115882A1 · Shahinian · 2011 [cited by applicant]
US 20110123098A1 · Ernst et al. · 2011 [cited by applicant]
US 20110245844A1 · Jinno · 2011 [cited by examiner]
US 20120075432A1 · Bilbrey et al. · 2012 [cited by applicant]
US 20120095354A1 · Dunn et al. · 2012 [cited by applicant]
US 20120101348A1 · Yamaguchi et al. · 2012 [cited by applicant]
US 20120165681A1 · Keller · 2012 [cited by applicant]
US 20120206587A1 · Oz et al. · 2012 [cited by applicant]
US 20120307512A1 · Cogger et al. · 2012 [cited by applicant]
US 20120310098A1 · Popovic · 2012 [cited by applicant]
US 20130023732A1 · Kim et al. · 2013 [cited by applicant]
US 20130041267A1 · Ntziachristos et al. · 2013 [cited by applicant]
US 20130253313A1 · Kang et al. · 2013 [cited by applicant]
US 20130274596A1 · Azizian et al. · 2013 [cited by applicant]
US 20130296712A1 · Durvasula · 2013 [cited by applicant]
US 20140031665A1 · Pinto et al. · 2014 [cited by applicant]
US 20140051923A1 · Mirza et al. · 2014 [cited by applicant]
US 20140052005A1 · Yokota · 2014 [cited by applicant]
US 20140071257A1 · Yokota · 2014 [cited by applicant]
US 20140092281A1 · Nisenzon et al. · 2014 [cited by applicant]
US 20140194747A1 · Kruglick et al. · 2014 [cited by applicant]
US 20140221749A1 · Grant et al. · 2014 [cited by applicant]
US 20140309495A1 · Kirma et al. · 2014 [cited by applicant]
US 20140378845A1 · Nadkarni · 2014 [cited by applicant]
US 20150099925A1 · Davidson et al. · 2015 [cited by applicant]
US 20150164329A1 · Schmidt et al. · 2015 [cited by applicant]
US 20150238276A1 · Atarot et al. · 2015 [cited by applicant]
US 20150377613A1 · Small et al. · 2015 [cited by applicant]
US 20150381909A1 · Butte et al. · 2015 [cited by applicant]
US 20160100908A1 · Tesar · 2016 [cited by applicant]
US 20160128553A1 · Geng · 2016 [cited by applicant]
US 20160139039A1 · Ikehara et al. · 2016 [cited by applicant]
US 20160239978A1 · Cole et al. · 2016 [cited by applicant]
US 20160260206A1 · Jung et al. · 2016 [cited by applicant]
US 20160262615A1 · Jung et al. · 2016 [cited by applicant]
US 20160278678A1 · Valdes et al. · 2016 [cited by applicant]
US 20160300348A1 · Nadeau et al. · 2016 [cited by applicant]
US 20160302880A1 · Uhlemann et al. · 2016 [cited by applicant]
US 20160307325A1 · Wang et al. · 2016 [cited by applicant]
US 20160307326A1 · Wang · 2016 [cited by applicant]
US 20160309068A1 · Nadeau et al. · 2016 [cited by applicant]
US 20160335472A1 · Lee et al. · 2016 [cited by applicant]
US 20170014030A1 · Rentschler et al. · 2017 [cited by applicant]
US 20170020393A1 · Rentschler et al. · 2017 [cited by applicant]
US 20170026633A1 · Riza · 2017 [cited by applicant]
US 20170030710A1 · Rentschler et al. · 2017 [cited by applicant]
US 20170032531A1 · Nagata et al. · 2017 [cited by applicant]
US 20170059305A1 · Nonn et al. · 2017 [cited by applicant]
US 20170059849A1 · Daidoji et al. · 2017 [cited by applicant]
US 20170079724A1 · Yang et al. · 2017 [cited by applicant]
US 20170095299A1 · Hendrick et al. · 2017 [cited by applicant]
US 20170100024A1 · Shahmoon et al. · 2017 [cited by applicant]
US 20170143237A1 · Yokota · 2017 [cited by applicant]
US 20170155818A1 · Bonnet · 2017 [cited by applicant]
US 20170164836A1 · Krishnaswamy et al. · 2017 [cited by applicant]
US 20170172382A1 · Nir et al. · 2017 [cited by applicant]
US 20170172384A1 · Yokota · 2017 [cited by applicant]
US 20170172394A1 · Scott et al. · 2017 [cited by applicant]
US 20170209031A1 · Nakamura et al. · 2017 [cited by applicant]
US 20170224274A1 · Chen et al. · 2017 [cited by applicant]
US 20170227942A1 · Thomson et al. · 2017 [cited by applicant]
US 20170228879A1 · Sato · 2017 [cited by applicant]
US 20170251900A1 · Hansen et al. · 2017 [cited by applicant]
US 20170280970A1 · Sartor et al. · 2017 [cited by applicant]
US 20170311778A1 · Hasser et al. · 2017 [cited by applicant]
US 20170328704A1 · Atiya et al. · 2017 [cited by applicant]
US 20170347043A1 · Rephaeli et al. · 2017 [cited by applicant]
US 20170351103A1 · Duckett et al. · 2017 [cited by applicant]
US 20170366773A1 · Kiraly et al. · 2017 [cited by applicant]
US 20180003943A1 · Chan · 2018 [cited by applicant]
US 20180008371A1 · Manus · 2018 [cited by applicant]
US 20180042466A1 · Kang et al. · 2018 [cited by applicant]
US 20180047165A1 · Sato · 2018 [cited by applicant]
US 20180104009A1 · Abhari et al. · 2018 [cited by applicant]
US 20180125586A1 · Sela et al. · 2018 [cited by applicant]
US 20180165823A1 · Ludwig · 2018 [cited by applicant]
US 20180174318A1 · Wang et al. · 2018 [cited by applicant]
US 20180235715A1 · Amiot et al. · 2018 [cited by applicant]
US 20180243043A1 · Michihata et al. · 2018 [cited by applicant]
US 20180279954A1 · Hayam · 2018 [cited by examiner]
US 20180360299A1 · Kishima · 2018 [cited by applicant]
US 20190000308A1 · Duckett, III et al. · 2019 [cited by applicant]
US 20190239730A1 · Myung et al. · 2019 [cited by applicant]
US 20190246873A1 · Lu · 2019 [cited by examiner]
US 20190265490A1 · Duckett, III · 2019 [cited by applicant]
US 20200107710A1 · Duckett, III et al. · 2020 [cited by applicant]
US 20200143545A1 · Weng et al. · 2020 [cited by applicant]
US 20200305721A1 · Chen et al. · 2020 [cited by applicant]
US 20200315432A1 · Tully et al. · 2020 [cited by applicant]
US 20210030277A1 · Ferguson, Jr. et al. · 2021 [cited by applicant]
US 20210282630A1 · Kikuchi et al. · 2021 [cited by applicant]
US 20210282654A1 · Cha et al. · 2021 [cited by applicant]
US 20210338060A1 · Tully et al. · 2021 [cited by applicant]
US 20220287553A1 · Tully et al. · 2022 [cited by applicant]
US 20220377217A1 · Dehghani et al. · 2022 [cited by applicant]
US 20220378280A1 · Tully et al. · 2022 [cited by applicant]
US 20230105882A1 · Abe · 2023 [cited by applicant]
US 20240353669A1 · Dehghani et al. · 2024 [cited by applicant]
CN 102770071A · 2012 [cited by applicant]
CN 103169446A · 2013 [cited by applicant]
CN 107124547A · 2017 [cited by applicant]
CN 107510430A · 2017 [cited by applicant]
EP 1489406A1 · 2004 [cited by applicant]
EP 2625998A1 · 2013 [cited by applicant]
EP 2604177B1 · 2016 [cited by applicant]
JP H10290780A · 1998 [cited by applicant]
JP 2006187427A · 2006 [cited by applicant]
JP 2007037783A · 2007 [cited by applicant]
JP 2007229135A · 2007 [cited by applicant]
JP 2009022652A · 2009 [cited by applicant]
JP 2009095554A · 2009 [cited by applicant]
JP 2010017377A · 2010 [cited by applicant]
JP 2015231498A · 2015 [cited by applicant]
JP 2018042676A · 2025 [cited by applicant]
KR 20170051264A · 2017 [cited by applicant]
KR 20180066645A · 2018 [cited by applicant]
WO WO2010096447A2 · 2010 [cited by applicant]
WO WO2010096453A1 · 2010 [cited by applicant]
WO WO2012096878A2 · 2012 [cited by applicant]
WO WO2014152753A1 · 2014 [cited by applicant]
WO WO2016061052A1 · 2016 [cited by applicant]
WO WO2016153741A1 · 2016 [cited by applicant]
WO WO2017075602A1 · 2017 [cited by applicant]
WO WO2018021035A1 · 2018 [cited by applicant]
WO WO2019045971A1 · 2019 [cited by applicant]
WO WO2020006454A1 · 2020 [cited by applicant]
WO WO2020210168 · 2020 [cited by applicant]
WO WO2021035094A1 · 2021 [cited by applicant]
WO 2021108450A1 · 2021 [cited by applicant]
WO WO2022029308A1 · 2022 [cited by applicant]
WO WO2022058499A1 · 2022 [cited by applicant]
WO WO2023091515A1 · 2023 [cited by applicant]
WO WO2023205456A1 · 2023 [cited by applicant]
Bray et al. Endoscopic laser speckle imaging of tissue blood flow: applications in the human knee. Journal of Orthopaedic Research, pp. 1650-1659 (2006). [cited by applicant]
Cha et al. Dual-display laparascopic laser speckle contrast imaging for real-time surgical assistance. Biomedical Optics Express, 9(12) pp. 1-20 (2018). Available at https://hsrc.himmelfarb.gwu.edu/cgi/viewcontent.cgi?a… [cited by applicant]
Dunn, et al. Laser speckle contrast imaging in biomedical optics. Journal of Biomedical Optics 15(1), 011109 (Jan./Feb. 2010). [cited by applicant]
Holstein-Rathlou et al. Nephron blood flow dynamics measured by laser speckle contrast imaging. Am J Phsiol Renal Physiol 300: F319-F329, 2011. [cited by applicant]
Kadambi et al. Rethinking machine vision time of flight with GHz heterodying. IEEE Access. vol. 5, 1-13, Nov. 2017. [cited by applicant]
Li et al. SH-ToF: Micro Resolution Time-of-Flight Imaging with Superheterodyne Interferometry, IEEE ICCP, 2018: 1-10. [cited by applicant]
PCT/US2020/047275 International Search Report & Written Opinion dated Feb. 1, 2021. [cited by applicant]
PCT/US20/26920 Search Report and Written Opinion dated Jun. 26, 2020. [cited by applicant]
Richards et al. Intraoperative laser speckle contrast imaging with retrospective motion correction for quantitative assessment of cerebral blood flow. Neurophotonics 1(1), 015006 (Jul.-Sep. 2014). [cited by applicant]
Cited By (1)
US 12,727,755