IP Library Granted Patent US 12,440,462
Granted Patent B2
US 12,440,462 · App. 17/326,507 · Granted Oct 14, 2025

Compositions and methods for remediating chemical warfare agent exposed skin

Inventors: Scott Noblitt (Fort Collins, CO); Edwin Neas (Nunn, CO)
Assignee: Armis Biopharma, Inc.
A61K31/19A61K9/06A61K31/327A61K33/40A61P17/02A61P39/02
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Quick Facts
Patent No.
US 12,440,462
App. No.
17/326,507
Granted
Oct 14, 2025
Kind
B2
Abstract

The present invention relates to chemical and biological warfare agent decontaminating compositions and methods for using the same to decontaminate animal skin and wounds thereon exposed to the agents. The compositions may comprise a peracid, a hydroperoxide, and a peroxyacid.

Claims (20)

1. A kit for chemical warfare agent decontamination, said kit comprising a chemical warfare agent decontaminating composition, packaged with a synthetic absorbent applicator comprising a non-woven fabric, cloth, mitt or towelette for application of the composition to a wound suffered by an exposed animal subject, an absorbent pad for removal of the composition and any chemical warfare agent from the wound, and a nerve gas antidote packaged for administering to the exposed subject,

wherein the decontaminating composition comprises active decontaminating compounds consisting of:

peracetic acid in an amount ranging from about 1% to about 6% by weight;

hydrogen peroxide in an amount ranging from about 3% to about 15% by weight;

acetic acid in an amount ranging from about 3% to about 15% by weight; and

the molar ratio of hydrogen peroxide to acetic acid ranges from 0.5:1 to about 2:1; and

the decontaminating composition further comprises a stabilizer and ingredients to formulate the composition as an aerosol or liquid spray, application granules, a gel, liquid, lotion or irrigation gel.

2. The kit of claim 1 , wherein the absorbent applicator is saturated with the composition.

3. The kit of claim 1 , wherein the absorbent applicator is a mitt.

4. The kit of claim 1 , further comprising a container for safe disposal of used applicators.

5. The kit of claim 1 , wherein the absorbent applicator is saturated and contained inside of a bottle or a pouch filled with the composition.

6. The kit of claim 1 , wherein the absorbent applicator is a towelette.

7. The kit of claim 1 , wherein:

the hydrogen peroxide is present in an amount ranging from about 7% to about 15% by weight; and

the acetic acid is present in an amount ranging from about 7% to about 15% by weight.

8. The kit of claim 1 , wherein the stabilizer is selected from the group consisting of etidronic acid, disodium ethylenediamine-tetraacetic acid, ethylenediaminetetraacetic acid, tetrasodium ethylenediaminetetraacetate, citramalic acid, dipicolinic acid, dipicolinic acid N-oxide, and a combination thereof.

9. The kit of claim 1 , wherein the decontaminating composition further comprises a surfactant.

10. The kit of claim 9 , wherein the surfactant is sodium dodecyl sulfate.

11. The kit of claim 1 , wherein the absorbent pad for removal of the composition is soaked in water or saline.

12. The kit of claim 1 , wherein the molar ratio of hydrogen peroxide to acetic acid is above 1:1 to about 2:1.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2021
From: NOBLITT, SCOTT; NEAS, EDWIN
To: ARMIS BIOPHARMA, INC.
Reel/Frame 057894/0735 →
Continuity (9)
Continuation In Part PCTUS2021012540 · Jan 7, 2021
Continuation 16900816 · Jun 12, 2020
Continuation 16736546 · Jan 7, 2020
Continuation In Part 16736546 · Jan 7, 2020
Continuation In Part PCTUS2018041163 · Jul 7, 2018
Provisional Application 63004858 · Apr 3, 2020
Provisional Application 62861810 · Jun 14, 2019
Provisional Application 62530045 · Jul 7, 2017
Related Publication 20220023174A1 · Jan 27, 2022
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