IP Library Granted Patent US 12,440,473
Granted Patent B2
US 12,440,473 · App. 17/461,325 · Granted Oct 14, 2025

Fatty acid analogs and their use in the treatment of cognitive impairment, behavioral conditions, and chronic pain

Inventor: Stephanie Venn-Watson (San Diego, CA)
Assignee: Epitracker, Inc.
A61K31/41A61K31/20A61P3/00
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Quick Facts
Patent No.
US 12,440,473
App. No.
17/461,325
Granted
Oct 14, 2025
Kind
B2
Abstract

Compositions comprising fatty acid analogs are provided for treating conditions involving impaired cognition, movement disorders, chronic pain, depression, decreased appetite, addiction, seizure, and convulsion, and other conditions. Methods for the diagnosis and monitoring of impaired cognition, movement disorders, chronic pain, depression, decreased appetite, addiction, seizure, convulsion, and other conditions are also provided.

Claims (24)

1. A method of treatment of a condition selected from the group consisting of impaired cognition, movement disorders, chronic pain, depression, decreased appetite, convulsion, seizure, anorexia, cachexia, and addiction, comprising:

administering to a patient in need thereof, a pharmaceutical composition comprising an effective amount of a compound having a structure selected from the group consisting of:

and pharmaceutically acceptable salts thereof.

2. The method of claim 1 , wherein the pharmaceutical composition is in a unit dosage form.

3. The method of claim 1 , comprising from 0.01 mg to 10000 mg of the compound of Formula (I), or pharmaceutically acceptable salt thereof.

4. The method of claim 1 , for the treatment of cognitive impairment.

5. The method of claim 4 , wherein the cognitive impairment is Alzheimer's disease.

6. The method of claim 1 , for treatment of a movement disorder.

7. The method of claim 6 , wherein the movement disorder is multiple sclerosis or Parkinson's disease.

8. The method of claim 1 , for treatment of addiction.

9. The method of claim 8 , wherein the addiction is opioid addiction.

10. The method of claim 1 , for treatment of anorexia or cachexia.

11. The method of claim 10 , wherein the condition with anorexia or cachexia is selected from the group consisting of cancer, AIDS, and advanced age.

12. The method of claim 1 , wherein the condition is chronic pain.

13. The method of claim 1 , wherein the condition is depression.

14. The method of claim 1 , wherein the compound of Formula (I) is:

15. The method of claim 14 , for the treatment of chronic pain.

16. The method of claim 14 , for the treatment of depression.

17. The method of claim 1 , wherein the compound of Formula (I) is:

18. The method of claim 17 , for treatment of addiction.

19. The method of claim 1 , wherein the compound of Formula (I) is:

20. The method of claim 19 , for the treatment of depression.

21. The method of claim 1 , wherein the compound of Formula (I) is:

22. The method of claim 21 , for treatment of depression.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 24, 2025
From: VENN-WATSON, STEPHANIE
To: EPITRACKER, INC.
Reel/Frame 073022/0381 →
Continuity (4)
Continuation PCTUS2020020697 · Mar 2, 2020
Provisional Application 62824247 · Mar 26, 2019
Provisional Application 62813566 · Mar 4, 2019
Related Publication 20210386710A1 · Dec 16, 2021
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