Granted Patent B2

US 12,491,324 · App. 19/052,148 · Granted Dec 9, 2025

Inventors: Louis Thomas Germinario (Kingsport, TN); John H. Hebrank (Durham, NC); Charles Eric Hunter (Boone, NC); Jack C. Hunter (Boone, NC); Chengjie Li (Shenzhen, CN); Christopher W. Maurer (Irvine, CA)

Assignee: PNEUMA RESPIRATORY, INC.

A61M11/005A24F40/05A24F40/10A24F40/30A61B5/082A61B5/087A61M11/001A61M11/003A61M15/0003A61M15/001A61M15/002A61M15/0021A61M15/0065A61M15/0081A61M15/0085A61M15/0091A61M15/025A61M16/0051A61M16/0066A61M16/021A61M16/107A61M16/108A61M16/14A61M16/142B05B17/06G16H50/20G16H50/30A61B5/0816A61B5/091A61M11/002A61M15/00A61M15/0035A61M2016/0018A61M2016/0021A61M2016/0027A61M2016/0036A61M2016/0039A61M16/022A61M16/024A61M16/10A61M16/1075A61M2205/0233A61M2205/0238A61M2205/0294A61M2205/103A61M2205/27A61M2205/276A61M2205/33A61M2205/3306A61M2205/3313A61M2205/3327A61M2205/3331A61M2205/3334A61M2205/3553A61M2205/3569A61M2205/3584A61M2205/3592A61M2205/502A61M2205/505A61M2205/52A61M2205/583A61M2205/584A61M2205/587A61M2205/6018A61M2205/6072A61M2205/7536A61M2205/8206A61M2206/11A61M2207/00A61M2230/06A61M2230/205A61M2230/30A61M2230/40

Abstract

Claims (43)

1 . A droplet delivery device for delivering a fluid as an ejected stream of droplets comprising:

a housing including an airflow exit at a mouthpiece and an airflow entrance into the housing, wherein the airflow exit and airflow entrance are in fluid communication via an airflow channel within the housing;

a fluid reservoir disposed within or in communication with the housing for receiving a volume of the fluid;

a non-heated aperture plate including a plurality of openings in fluid communication with the fluid reservoir and the airflow channel;

an electric actuator operably coupled to the aperture plate;

a power source within the housing coupled to the electric actuator, wherein the electric actuator is configured to be energized by the power source and produce a droplet plume from the fluid from the fluid reservoir when air is inhaled through the housing;

the droplet plume including a first plurality of droplet particles having a smaller mass mean aerodynamic diameter than 5 μm and a second plurality of droplet particles having a mass mean aerodynamic diameter greater than 5 μm;

the airflow channel including a change of airflow trajectory from between the aperture plate to the airflow exit that causes inertial filtering and removal of the second plurality of droplet particles from the droplet plume during energizing of the electric actuator; and

a fan coupled to the housing and in fluid communication with the airflow channel.

2 . The device of claim 1 , wherein the electric actuator is a piezoelectric actuator.

3 . The device of claim 2 , wherein the change of trajectory of the airflow channel is an angle of approximately 90°.

4 . The device of claim 2 , wherein the change of airflow trajectory is an angle less than 90°.

5 . The device of claim 4 , wherein the fluid reservoir contains the fluid including a drug.

6 . The device of claim 5 , wherein the drug is nicotine.

7 . The device of claim 5 , wherein the drug is a chemical from marijuana.

8 . The device of claim 5 , wherein the drug is a pharmaceutical.

9 . The device of claim 2 , wherein the fluid reservoir contains the fluid including a drug.

10 . The device of claim 9 , wherein the drug is nicotine.

11 . The device of claim 9 , wherein the drug is a chemical from marijuana.

12 . The device of claim 9 , wherein the drug is a pharmaceutical.

13 . The device of claim 1 , wherein the change of airflow trajectory is an angle of approximately 90°.

14 . The device of claim 1 , wherein the change of airflow trajectory is an angle less than 90°.

15 . The device of claim 1 , wherein the fluid reservoir contains the fluid including a drug.

16 . The device of claim 15 , wherein the drug is nicotine.

17 . The device of claim 15 , wherein the drug is a chemical from marijuana.

18 . The device of claim 15 , wherein the drug is a pharmaceutical.

19 . A droplet delivery device for delivering a fluid as an ejected stream of droplets comprising:

a housing including an airflow exit at a mouthpiece and an airflow entrance into the housing, wherein the airflow exit and airflow entrance are in fluid communication via an airflow channel within the housing;

a fluid reservoir disposed within or in communication with the housing for receiving a volume of the fluid;

a non-heated aperture plate including a plurality of openings in fluid communication with the fluid reservoir and the airflow channel;

an electric actuator operably coupled to the aperture plate;

a power source within the housing coupled to the electric actuator, wherein the electric actuator is configured to be energized by the power source and produce a droplet plume from the fluid from the fluid reservoir when air is inhaled through the housing;

the droplet plume including a first plurality of droplet particles having a smaller mass mean aerodynamic diameter than 5 μm and a second plurality of droplet particles having a mass mean aerodynamic diameter greater than 5 μm; and

a fan coupled to the housing and in fluid communication with the airflow channel that causes inertial filtering and removal of the second plurality of droplet particles from the droplet plume during energizing of the electric actuator.

20 . The device of claim 19 , wherein the electric actuator is a piezoelectric actuator.

21 . The device of claim 20 , wherein the fluid reservoir contains the fluid including a drug.

22 . The device of claim 21 , wherein the drug is nicotine.

23 . The device of claim 21 , wherein the drug is a chemical from marijuana.

24 . The device of claim 21 , wherein the drug is a pharmaceutical.

25 . The device of claim 19 , wherein the fluid reservoir contains the fluid including a drug.

26 . The device of claim 25 , wherein the drug is nicotine.

27 . The device of claim 25 , wherein the drug is a chemical from marijuana.

28 . The device of claim 25 , wherein the drug is a pharmaceutical.

Assignments (1)

Continuity (14)

References Cited (400)