Medical device making treatment recommendations based on sensed characteristics of a lesion
Embodiments described relate to a medical device including an invasive probe that, when inserted into an animal (e.g., a human or non-human animal, including a human or non-human mammal), may aid in diagnosing and/or treating a lesion of the animal (e.g., a growth or deposit within vasculature that fully or partially blocks the vasculature). The invasive probe may have one or more sensors to sense characteristics of the lesion, including by detecting one or more characteristics of tissues and/or biological materials of the lesion. The medical device may be configured to analyze the characteristics of a lesion and, based on the analysis, provide treatment recommendations to a clinician. Such treatment recommendations may include a manner in which to treat a lesion, such as which treatment to use to treat a lesion and/or a manner in which to use a treatment device.
1 . A method of operating a medical device for diagnosis and/or treatment of a lesion of an animal, the medical device comprising an invasive probe to be inserted into the animal and removed from the animal following diagnosis and/or treatment of the lesion, the method comprising:
generating, with the invasive probe of the medical device while the invasive probe is disposed within the animal, an impedance measurement of a plurality of biological materials of the lesion measured by the invasive probe at a plurality of locations of the lesion, wherein generating the impedance measurement comprises operating the invasive probe to apply an electrical signal at a plurality of frequencies and operating a plurality of sensors of the invasive probe to measure impedance of the plurality of biological materials of the lesion;
selecting, using at least one processor of the medical device, from among a plurality of other medical devices that may be used to treat lesions and based at least in part on an evaluation of the impedance measurement of the plurality of biological materials of the lesion, at least one of the plurality of other medical devices to recommend for treatment of the lesion, wherein the invasive probe of the medical device and each of the plurality of other medical devices are configured for separate insertion into the animal; and
outputting the at least one of the plurality of other medical devices for presentation to a user via a user interface.
2 . The method of claim 1 , wherein:
the lesion is a lesion of a duct of the animal, and the duct of the animal is vasculature of the animal; and
generating the impedance measurement while the invasive probe is disposed within the animal comprises generating the impedance measurement while the invasive probe is disposed within the vasculature of the animal.
3 . The method of claim 1 , wherein operating the plurality of sensors of the invasive probe to measure the impedance of the lesion comprises operating the plurality of sensors to measure, with each sensor, an impedance spectrum of a biological material, of the plurality of biological materials of the lesion, contacting the sensor.
4 . The method of claim 3 , further comprising:
identifying, based on the impedance measurement at the plurality of locations, the plurality of biological materials present in the lesion.
5 . The method of claim 4 , further comprising:
identifying the lesion, wherein identifying the lesion comprises identifying the lesion based at least in part on the plurality of biological materials present in the lesion.
6 . The method of claim 5 , wherein selecting the at least one of the plurality of other medical devices to recommend for treatment of the lesion comprises selecting the at least one of the plurality of other medical devices based at least in part on an identity of the lesion and/or on the plurality of biological materials present in the lesion.
7 . The method of claim 1 , wherein selecting the at least one of the plurality of other medical devices to recommend for treatment of the lesion based on the evaluation of the impedance measurement of the plurality of biological materials of the lesion comprises:
comparing the impedance measurement to one or more conditions associated with each of the plurality of other medical devices, the plurality of other medical devices each being associated with a different one or more conditions; and
in response to determining that the impedance measurement satisfies the one or more conditions associated with a medical device of the plurality of other medical devices, selecting the medical device of the plurality of other medical devices as the at least one of the plurality of other medical devices to recommend for treatment of the lesion.
8 . The method of claim 1 , wherein the plurality of other medical devices comprises:
at least one ablative medical device; and
at least one non-ablative medical device.
9 . The method of claim 1 , wherein the plurality of other medical devices comprises a stent-retriever.
10 . The method of claim 1 , wherein the plurality of other medical devices comprises an aspiration catheter.
11 . The method of claim 1 , wherein the plurality of other medical devices comprises a stent.
12 . The method of claim 1 , further comprising:
transmitting measurement data from the plurality of sensors to a measurement circuit of the invasive probe, wherein the measurement circuit is disposed within vasculature of the animal; and
identifying, with the measurement circuit disposed within the vasculature of the animal, the biological materials of the lesion.
13 . At least one non-transitory computer-readable storage medium having encoded thereon executable instructions that, when executed by at least one processor, cause the at least one processor to carry out a method of operating a medical device for diagnosis and/or treatment of a lesion of an animal, the medical device comprising an invasive probe to be inserted into the animal and removed from the animal following diagnosis and/or treatment of the lesion, the method comprising:
generating, with the invasive probe of the medical device while the invasive probe is disposed within the animal, an impedance measurement of a plurality of biological materials of the lesion measured by the invasive probe at a plurality of locations of the lesion, wherein generating the impedance measurement comprises operating the invasive probe to apply an electrical signal at a plurality of frequencies and operating a plurality of sensors of the invasive probe to measure impedance of the plurality of biological materials of the lesion;
selecting, using at least one processor of the medical device, from among a plurality of other medical devices that may be used to treat lesions and based at least in part on an evaluation of the impedance measurement of the plurality of biological materials of the lesion, at least one of the plurality of other medical devices to recommend for treatment of the lesion, wherein selecting the at least one of the plurality of other medical devices to recommend for treatment of the lesion comprises:
comparing the impedance measurement to one or more conditions associated with each of the plurality of other medical devices, the plurality of other medical devices each being associated with a different one or more conditions; and
in response to determining that the impedance measurement satisfies the one or more conditions associated with a medical device of the plurality of other medical devices, selecting the medical device of the plurality of other medical devices as the at least one of the plurality of other medical devices to recommend for treatment of the lesion; and
outputting the at least one of the plurality of other medical devices for presentation to a user via a user interface.
14 . An apparatus comprising:
at least one processor; and
at least one non-transitory computer-readable storage medium having encoded thereon executable instructions that, when executed by the at least one processor, cause the at least one processor to carry out a method of operating a medical device for diagnosis and/or treatment of a lesion of an animal, the medical device comprising an invasive probe to be inserted into the animal and removed from the animal following diagnosis and/or treatment of the lesion, the method comprising:
generating, with the invasive probe of the medical device while the invasive probe is disposed within the animal, an impedance measurement of a plurality of biological materials of the lesion measured by the invasive probe at a plurality of locations of the lesion, wherein generating the impedance measurement comprises operating the invasive probe to apply an electrical signal at a plurality of frequencies and operating a plurality of sensors of the invasive probe to measure impedance of the plurality of biological materials of the lesion;
selecting, using at least one processor of the medical device, from among a plurality of other medical devices that may be used to treat lesions and based at least in part on an evaluation of the impedance measurement of the plurality of biological materials of the lesion, at least one of the plurality of other medical devices to recommend for treatment of the lesion, wherein the invasive probe of the medical device and each of the plurality of other medical devices are configured for separate insertion into the animal; and
outputting the at least one of the plurality of other medical devices for presentation to a user via a user interface.