Registration of intraluminal physiological data to longitudinal image body lumen using extraluminal imaging data
A system includes a processor circuit that receives intravascular imaging data from an intravascular imaging catheter, an x-ray image from an x-ray imaging device, and intravascular pressure data from an intravascular pressure-sensing guidewire. The processor circuit correlates the intravascular imaging data and the intravascular pressure data to locations along a body lumen shown in the x-ray image. The processor circuit generates a longitudinal view of the body lumen based on the intravascular imaging data and outputs a screen display including the longitudinal view of the body lumen with an overlaid graphical representation corresponding to the intravascular pressure measurements.
1 . A system comprising:
an intravascular imaging catheter configured for intravascular ultrasound (IVUS) or optical coherence tomography (OCT);
an intravascular pressure-sensing guidewire; and
a processor circuit configured for communication with the intravascular imaging catheter and the intravascular pressure-sensing guidewire, wherein the processor circuit is configured to:
control the intravascular imaging catheter to obtain a plurality of intravascular images during movement of the intravascular imaging catheter through a blood vessel of a patient;
co-register the plurality of intravascular images to first corresponding positions along the blood vessel;
identify, based on co-registering the plurality of intravascular images, a starting position of the movement of the intravascular imaging catheter and a length along the blood vessel traveled by the intravascular imaging catheter during the movement of the intravascular imaging catheter:
control the intravascular pressure-sensing guidewire to obtain a plurality of intravascular pressure measurements during movement of the intravascular pressure-sensing guidewire through the blood vessel;
co-register the plurality of intravascular pressure measurements to second corresponding positions along the blood vessel;
identify, based on co-registering the plurality of intravascular pressure measurements, a starting position of the movement of the intravascular pressure-sensing quidewire and a length along the blood vessel traveled by the intravascular pressure-sensing quidewire during the movement of the intravascular pressure-sensing guidewire;
determine an offset between the starting position of the movement of the intravascular imaging catheter and the starting position of the movement of the intravascular pressure-sensing guidewire;
generate a longitudinal view of the blood vessel based on the plurality of intravascular images such that the longitudinal view comprises a stack of the plurality of intravascular images;
generate a graphical representation based on the plurality of intravascular pressure measurements; and
output, to a display in communication with the processor circuit, a screen display comprising:
the longitudinal view of the blood vessel; and
the graphical representation overlaid on the longitudinal view,
wherein the graphical representation is overlaid on the longitudinal view based on the offset.
2 . The system of claim 1 ,
wherein the graphical representation is overlaid on the longitudinal view such that a location along the graphical representation corresponds to a location along the longitudinal view, and
wherein the location along the graphical representation and the location along the longitudinal view are representative of a same corresponding position along the blood vessel.
3 . The system of claim 1 ,
wherein the graphical representation is overlaid on the longitudinal view based on:
the length along the blood vessel traveled by the intravascular imaging catheter;
and the length along the blood vessel traveled by the intravascular pressure-sensing guidewire.
4 . The system of claim 1 ,
wherein the processor circuit is further configured to:
identify, based on co-registering the plurality of intravascular images, an ending position of the movement of the intravascular imaging catheter; and
identify, based on co-registering the plurality of intravascular pressure measurements, an ending position of the movement of the intravascular pressure-sensing guidewire;
wherein the graphical representation is overlaid on the longitudinal view based on:
the starting position of the movement of the intravascular imaging catheter;
the ending position of the movement of the intravascular imaging catheter;
the starting position of the movement of the intravascular pressure-sensing guidewire; and
the ending position of the movement of the intravascular pressure-sensing guidewire.
5 . The system of claim 1 , wherein the graphical representation comprises a plot based on the plurality of intravascular pressure measurements.
6 . The system of claim 5 ,
wherein the processor circuit is further configured to calculate a plurality of pressure ratios using the plurality of intravascular pressure measurements, and
wherein the plot based on the plurality of intravascular pressure measurements comprises a plot of the plurality of pressure ratios.
7 . The system of claim 1 ,
wherein the processor circuit is configured to generate a further graphical representation based on the plurality of intravascular pressure measurements,
wherein the screen display comprises the further graphical representation overlaid on the longitudinal view,
wherein the graphical representation comprises a conditioned plot based on the plurality of intravascular pressure measurements, and
wherein the further graphical representation comprises a raw plot based on the plurality of intravascular pressure measurements.
8 . The system of claim 1 ,
wherein the processor circuit is further configured to calculate a plurality of pressure ratios using the plurality of intravascular pressure measurements, and
wherein the graphical representation comprises a plurality of shapes representative of amounts of change between the plurality of pressure ratios.
9 . The system of claim 1 ,
wherein the processor circuit is configured to receive, from a user input device in communication with the processor circuit, a user input selecting a portion of the longitudinal view; and
wherein the screen display further comprises an indicator overlaid on the longitudinal view and identifying the portion of the longitudinal view.
10 . The system of claim 1 , wherein the screen display further comprises:
an extraluminal image of the blood vessel;
an indicator of the length along the blood vessel traveled by the intravascular imaging catheter overlaid on the extraluminal image; and
an indicator of the length along the blood vessel traveled by the intravascular pressure-sensing guidewire overlaid on the extraluminal image.
11 . The system of claim 1 , wherein the screen display further comprises:
an extraluminal image of the blood vessel; and
an intravascular image of the plurality of intravascular images.