Spray drying system
The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.
1 . A spray drying system for drying a plasma from one or more donors, comprising:
A) a spray drying apparatus having a drying gas source providing a drying gas, a plasma source providing the plasma and a pressurized aerosol gas source providing a pressurized aerosol gas; and
B) a spray drying disposable device, having a spray drying head and a plasma drying chamber, for use in the spray drying system; wherein the plasma drying chamber has a section that becomes a container having a dried plasma unit after the plasma is spray dried therein.
2 . The spay drying system of claim 1 , wherein the plasma drying chamber comprises:
A) a first end in communication with the spray drying head, wherein the spray drying head provides atomized plasma droplets and the drying gas to the plasma drying chamber, wherein when in use the atomized plasma droplets are dried into dried plasma particles;
and
B) the section disposed between the first end and a gas outlet and configured to become a dried plasma unit after plasma is spray dried;
wherein, when in use, the atomized plasma droplets evaporate in the plasma drying chamber when coming into contact with the drying gas emitted from the spray drying head, to thereby obtain dried plasma particles and humid air.
3 . The spay drying system of claim 2 , wherein the spray drying head comprises:
a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source, wherein the pressurized aerosol gas flows in a vortex pattern, wherein, when in use, the pressurized aerosol gas atomizes the plasma entering the plasma drying chamber to obtain the atomized plasma droplets.
4 . The spay drying system of claim 2 , a spray drying disposable device further comprises:
A) a capture filter, residing in the plasma drying chamber, wherein, when in use, the capture filter captures the dried plasma particles and allows the humid air to pass; and
B) the gas outlet, wherein said gas outlet is attached to an exhaust port of the spray drying apparatus during operation, wherein, when in use, the humid air flows through the gas outlet.
5 . The spray drying system of claim 1 , further comprising a finishing apparatus configured to convert the plasma drying chamber having spray dried plasma therein into the container having a dried plasma unit.
6 . The spray drying system of claim 5 , wherein the finishing apparatus comprises:
A) an impactor, when in use and when the spray drying disposable device having spray dried plasma is attached, is configured to allow for the movement of the dried plasma within the plasma drying chamber,
B) a sealer that seals the spray dried plasma within a portion of the plasma drying chamber to thereby create the container having the dried plasma unit; and
C) a separator which separates the container having the dried plasma unit from the plasma drying chamber.
7 . A spray drying system for drying a plasma from one or more donors to obtain a spray dried plasma, comprising:
A) a spray drying apparatus having a drying gas source providing a drying gas, a plasma source providing the plasma and a pressurized aerosol gas source providing a pressurized aerosol gas;
B) a spray drying disposable device, having a spray drying head and a plasma drying chamber, for use in the spray drying system;
wherein the spray drying system is configured for transport.
8 . The spray drying system of claim 7 , wherein the spray drying system is configured for transport to battlefields, natural disaster areas, rural areas, and first responder settings.
9 . The spray drying system of claim 7 , wherein the spray drying system provides a container having a spray dried plasma.
10 . The spray drying system of claim 9 , wherein the spray drying system aseptically provides the container having a spray dried plasma.
11 . The spray drying system of claim 7 , further comprising a finishing apparatus configured to convert the plasma drying chamber having the spray dried plasma therein into the container having a dried plasma unit.
12 . The spray drying system of claim 11 , wherein the finishing apparatus comprises:
A) an impactor, when in use and when the spray drying disposable device having spray dried plasma is attached, is configured to allow for the movement of the dried plasma within the plasma drying chamber,
B) a sealer that seals the spray dried plasma within a portion of the plasma drying chamber to thereby create the container having the dried plasma unit; and
C) a separator which separates the container having the dried plasma unit from the plasma drying chamber.
13 . A transportable spray drying system for drying a plasma from one or more donors to obtain a spray dried plasma, comprising:
A) a spray drying apparatus having a drying gas source providing a drying gas, a plasma source providing the plasma and a pressurized aerosol gas source providing a pressurized aerosol gas;
B) a spray drying disposable device, having a spray drying head and a plasma drying chamber, for use in the spray drying system;
wherein the spray drying system provides a container having the spray dried plasma.
14 . The spray drying system of claim 13 , wherein the spray drying system aseptically provides a container having the spray dried plasma.
15 . The spray drying system of claim 13 , further comprising a finishing apparatus configured to convert the plasma drying chamber having spray dried plasma therein into the container having a dried plasma unit.
16 . The spray drying system of claim 15 , wherein the finishing apparatus comprises:
A) an impactor, when in use and when the spray drying disposable device having spray dried plasma is attached, is configured to allow for the movement of the dried plasma within the plasma drying chamber,
B) a sealer that seals the spray dried plasma within a portion of the plasma drying chamber to thereby create the container having the dried plasma unit; and
C) a separator which separates the container having the dried plasma unit from the plasma drying chamber.
17 . The spray drying system of claim 13 , wherein the spray drying system is configured for transport to battlefields, natural disaster areas, rural areas, and first responder settings.
18 . A spray drying system for drying a plasma from one or more donors to obtain a spray dried plasma, comprising:
A) a spray drying apparatus having a drying gas source providing a drying gas, a plasma source providing the plasma and a pressurized aerosol gas source providing a pressurized aerosol gas;
B) a spray drying disposable device, having a spray drying head and a plasma drying chamber, for use in the spray drying system; and
C) a finishing apparatus configured to convert the plasma drying chamber, when in use, into a container having a dried plasma unit.
19 . The spay drying system of claim 18 , wherein the plasma drying chamber comprises:
A) a first end in communication with the spray drying head, wherein the spray drying head provides atomized plasma droplets and the drying gas to the plasma drying chamber, wherein when in use the atomized plasma droplets are dried into dried plasma particles;
and
B) the section disposed between the first end and a gas outlet and configured to become a dried plasma unit after plasma is spray dried;
wherein, when in use, the atomized plasma droplets evaporate in the plasma drying chamber when coming into contact with the drying gas emitted from the spray drying head, to thereby obtain dried plasma particles and humid air.
20 . The spay drying system of claim 19 , wherein the spray drying head comprises:
a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source, wherein the pressurized aerosol gas flows in a vortex pattern, wherein, when in use, the pressurized aerosol gas atomizes the plasma entering the plasma drying chamber to obtain the atomized plasma droplets.
21 . The spay drying system of claim 19 , a spray drying disposable device further comprises:
A) a capture filter, residing in the plasma drying chamber, wherein, when in use, the capture filter captures the dried plasma particles and allows the humid air to pass; and
B) the gas outlet, wherein said gas outlet is attached to an exhaust port of the spray drying apparatus during operation, wherein, when in use, the humid air flows through the gas outlet.
22 . The spray drying system of claim 18 , wherein the finishing apparatus comprises:
A) an impactor, when in use and when the spray drying disposable device having spray dried plasma is attached, is configured to allow for the movement of the dried plasma within the plasma drying chamber,
B) a sealer that seals the spray dried plasma within a portion of the plasma drying chamber to thereby create the container having the dried plasma unit; and
C) a separator which separates the container having the dried plasma unit from the plasma drying chamber.
23 . The spray drying system of claim 18 , wherein the spray drying system is configured for transport to battlefields, natural disaster areas, rural areas, and first responder settings.