Oral care compositions
An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.
1 . An oral care composition comprising:
an orally acceptable carrier;
zinc phosphate present in an amount of from about 0.05 wt. % to about 10 wt. %;
a first stannous ion source comprising stannous fluoride present in an amount of from about 0.01 wt. % to about 5 wt. %;
a second stannous ion source comprising stannous chloride present in an amount from about 0.01 wt. % to about 5 wt. %;
water present in an amount of 15 wt. % or more; and
one or more surfactants selected from sodium lauryl sulfate, sodium laureth sulfate, or cocamidopropyl betaine, and combinations thereof;
wherein all weight percentages are based on the total weight of the oral care composition.
2 . A composition according to claim 1 , wherein the zinc phosphate is a preformed salt of zinc phosphate.
3 . A composition according to claim 1 , wherein the amount of zinc phosphate is present in an amount of from 0.1 to 8% by weight.
4 . A composition according to claim 1 , wherein the amount of the first stannous ion source is from 0.05% to 4% by weight.
5 . A composition according to claim 1 , wherein the amount of the second stannous ion source is from 0.05% to 4% by weight.
6 . A composition according to claim 1 , wherein the amount of the water is 15-90 wt. %.
7 . A composition according to claim 1 , further comprising one or more humectants selected from sorbitol, glycerol, xylitol and propylene glycol, and combinations thereof.
8 . A composition according to claim 1 , further comprising an effective amount of one or more alkali phosphate salts selected from orthophosphates, pyrophosphates, tripolyphosphates, tetraphosphates and higher polyphosphates.
9 . A composition according to claim 8 , wherein the alkali phosphate salts comprise tetrasodium pyrophosphate or tetrapotassium pyrophosphate.
10 . A composition according to claim 1 , further comprising one or more sources of zinc ions in addition to the zinc phosphate.
11 . A composition according to claim 1 , further comprising an organic acid buffer system comprising a carboxylic acid and one or more conjugate base salts thereof.
12 . A composition according to claim 1 , wherein the oral care composition is a dentifrice.
13 . A method of treatment or prevention of erosive tooth demineralization, gingivitis, plaque, and/or dental caries, the method comprising the application to the oral cavity of a person in need thereof a composition according to claim 1 , one or more times per day.
14 . A method to (i) reduce or inhibit formation of dental caries, (ii) reduce, repair or inhibit pre-carious lesions of the enamel, (iii) reduce or inhibit demineralization and promote remineralization of the teeth, (iv) reduce hypersensitivity of the teeth, (v) reduce or inhibit gingivitis, (vi) promote healing of sores or cuts in the mouth, (vii) reduce levels of acid producing bacteria, (viii) to increase relative levels of arginolytic bacteria, (ix) inhibit microbial biofilm formation in the oral cavity, (x) raise and/or maintain plaque pH at levels of at least pH 5.5 following sugar challenge, (xi) reduce plaque accumulation, (xii) treat, relieve or reduce dry mouth, (xiii) clean the teeth and oral cavity (xiv) reduce erosion, (xv) prevents stains and/or whiten teeth, (xvi) immunize the teeth against cariogenic bacteria; and/or (xvii) promote systemic health, including cardiovascular health the method comprising applying an effective amount of the oral composition according to claim 1 to a surface of an oral cavity in need thereof.