IP Library Granted Patent US 12,629,321
Granted Patent B2
US 12,629,321 · App. 17/632,182 · Granted May 19, 2026

Compositions and related methods

Inventors: Norbert Huber (Basel, CH); Turan Matur (Binningen, CH); Ruth Hinrichs (Therwil, CH); Jeannine Loetscher (Ettingen, CH)
Assignee: Colgate-Palmolive Company
A61K8/21A61K8/20A61K8/27A61K8/41A61K8/8176A61Q11/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,629,321
App. No.
17/632,182
Granted
May 19, 2026
Kind
B2
Abstract

The present disclosure relates to storage-stable compositions comprising amines and zinc-containing compounds. Related methods of use and making are further disclosed.

Claims (9)

1 . An oral care composition comprising:

an amine base,

sodium fluoride in an amount of about 0.1 wt. % to about 0.5 wt. %,

zinc lactate in an amount of about 0.2 wt. % to about 0.5 wt. %,

a surfactant,

a humectant, and

hydrochloric acid,

wherein the composition comprises less than 0.001 wt. % stannous fluoride, the amine base, sodium fluoride, and hydrochloric acid form amine fluoride in situ , and the wt. percents are based on the total weight of the composition.

2 . The composition according to claim 1 , wherein the oral care composition is in the form of a toothpaste, a dentifrice, a mouthwash, a mouth rinse, a topical oral gel, a denture cleanser, or a dental spray.

Continuity (2)
Provisional Application 63127791 · Dec 18, 2020
Related Publication 20230355487A1 · Nov 9, 2023
References Cited (23)
US 4522806A · Muhlemann et al. · 1985 [cited by applicant]
US 6417207B1 · Garvey et al. · 2002 [cited by applicant]
US 10342750B2 · Prencipe et al. · 2019 [cited by applicant]
US 20120288548A1 · Boyd · 2012 [cited by examiner]
US 20130209375A1 · Moya Argilagos · 2013 [cited by examiner]
US 20170367948A1 · Thomson et al. · 2017 [cited by applicant]
US 20180021234A1 · Prencipe et al. · 2018 [cited by applicant]
US 20190269586A1 · Prencipe et al. · 2019 [cited by applicant]
US 20200197271A1 · Manus et al. · 2020 [cited by applicant]
CN 102159083 · 2011 [cited by applicant]
CN 102656142 · 2012 [cited by applicant]
CN 108078798 · 2018 [cited by applicant]
CN 110099721 · 2019 [cited by applicant]
SG 165839 · 2010 [cited by applicant]
WO 2001039737 · 2001 [cited by applicant]
WO 2009130319 · 2009 [cited by applicant]
WO WO2010112577A1 · 2010 [cited by examiner]
WO 2014088572 · 2014 [cited by applicant]
WO 2014094900 · 2014 [cited by applicant]
WO WO2017116444A1 · 2017 [cited by examiner]
WO 2017223497 · 2017 [cited by applicant]
Hampelska et al (“The Role of Oral Microbiota in Intra-Oral Halitosis”, Journal of Clinical Medicine, vol. 9(8), Aug. 2020), an article obtained at the website: https://pubmed.ncbi.nlm.nih.gov/32748883/) (Year: 2020). [cited by examiner]
International Search Report and the Written Opinion of the International Searching Authority issued in International Application PCT/US2021/064066 mailed Apr. 7, 2022. [cited by applicant]