Granted Patent B2

US 12,734,028 · App. 18/171,344 · Granted Sep 15, 2026

Inventors: Robert Rosen (Groningen, NL); Franck Emmanuel Gounou (Groningen, NL); Carmen Canovas Vidal (Groningen, NL); Aixa Alarcon Heredia (Groningen, NL)

Assignee: AMO Groningen B.V.

A61F2/1627A61F9/008A61B2017/00181A61F2009/00848

Abstract

Claims (48)

1 . A method for improving vision of a subject, the method comprising:

receiving, by a control system, parameters related to spectacle dependence of an eye of a subject having an implanted intraocular lens (IOL);

calculating, based on the parameters, a pattern of laser pulses and selected areas of the IOL to which the laser pulses are to be applied to change a phase profile of the IOL to increase spectacle independence;

estimating, by the control system, a phase delay based at least in part on measurements associated with subject-specific through-focus visual acuity; and

applying, based at least on one or more of the phase delay, the pattern of laser pulses, or the selected areas of the IOL, a plurality of laser pulses to the selected areas of the IOL to change a refractive index of the selected areas, by refractive index writing.

2 . The method of claim 1 , wherein applying the plurality of laser pulses comprises applying a plurality of focused laser pulses according to the pattern of laser pulses to at least one selected area of the IOL to produce the change in phase profile.

3 . The method of claim 1 or 2 , wherein the change in phase profile to improve spectacle independence is determined by performing functions comprising:

prior to the application of the laser pulses to the IOL, acquiring measurements associated with subject-specific through-focus visual acuity; and

predicting, based at least in part on the acquired measurements, an estimated phase profile for increasing near vision for the subject while maintaining distance vision, or for the increasing of distance vision for the subject while maintaining near vision and intermediate vision.

4 . The method of claim 1 , wherein the IOL is a multifocal IOL and the refractive index writing produces a phase profile on the IOL that changes the add power of the multifocal IOL.

5 . The method of claim 4 , wherein the change of the add power produced by the refractive index writing phase profile is calculated based on at least one of:

through focus visual acuity of the subject;

comfortable reading distance of the subject; and

subject biometry.

6 . The method of claim 5 , wherein the subject biometry comprises at least one of axial length of the subject's eye, IOL position, and corneal power.

7 . The method of claim 1 , wherein the change in phase profile is determined, prior to the application of the laser pulses to the IOL, based at least in part on at least one of:

subject-specific reading habits, including reading distances;

pupil size; and

subject-specific data indicating common lifestyle tasks performed by the subject and lighting conditions associated with respective tasks.

8 . The method of claim 1 , wherein the IOL is a diffractive IOL or a multifocal refractive IOL.

9 . The method of claim 1 , wherein the change in phase profile is estimated by calculating a phase difference between an existing phase profile of the implanted IOL and a desired phase profile expected after the refractive index writing.

10 . A method for improving vision of a subject, the method comprising:

receiving, by a control system, parameters related to spectacle dependence of an eye of a subject having an implanted intraocular lens (IOL);

calculating, based on the parameters, a pattern of laser pulses and selected areas of the IOL to which the laser pulses are to be applied to change a phase profile of the IOL to increase spectacle independence;

estimating, by the control system, a phase delay based at least in part on measurements associated with subject-specific through-focus visual acuity; and

applying, by a pulsed laser system under control of the control system, a plurality of laser pulses to the selected areas of the IOL to change a refractive index of the selected areas, by refractive index writing, wherein the measurements are acquired prior to the application of the laser pulses to the IOL.

11 . The method of claim 10 , wherein applying the plurality of laser pulses comprises applying a plurality of focused laser pulses according to the pattern of laser pulses to at least one selected area of the IOL to produce the change in phase profile.

12 . The method of claim 10 or 11 , wherein the change in phase profile to improve spectacle independence is determined by performing functions further comprising:

predicting, based at least in part on the measurements, an estimated phase profile for increasing near vision for the subject while maintaining distance vision, or the increasing of distance vision for the subject while maintaining near vision.

13 . The method of claim 10 or 11 , wherein the change in phase profile to improve spectacle independence is determined by performing functions further comprising:

predicting, based at least in part on the measurements, an estimated phase profile for increasing intermediate vision for the subject while maintaining distance vision, or the increasing of distance vision for the subject while maintaining intermediate vision.

14 . The method of claim 10 or 11 , wherein the change in phase profile to improve spectacle independence is determined by performing functions further comprising:

predicting, based at least in part on the measurements, an estimated phase profile for increasing intermediate vision for the patient while maintaining near vision, or the increasing of near vision for the patient while maintaining intermediate vision.

15 . The method of claim 10 , wherein the IOL is a multifocal IOL and the refractive index writing produces a phase profile to change the add power of the multifocal IOL.

16 . The method of claim 15 , wherein the change of the add power produced by the refractive index writing phase profile is calculated based on at least one of:

through-focus visual acuity of the subject;

comfortable reading distance of the subject; and

subject biometry.

17 . The method of claim 16 , wherein the subject biometry comprises at least one of axial length, IOL position, and corneal power.

18 . The method of claim 10 , wherein the change in phase profile is determined, prior to the application of the laser pulses to the IOL, based at least in part on at least one of:

subject-specific reading habits, including reading distances;

pupil size; and

subject-specific data indicating common lifestyle tasks performed by the subject and lighting conditions associated with respective tasks.

19 . A method for improving vision of a subject, the method comprising:

receiving, by a control system, parameters related to spectacle dependence of an eye of a subject having an implanted intraocular lens (IOL);

calculating, based on the parameters, a pattern of laser pulses and selected areas of the IOL to which the laser pulses are to be applied to change a phase profile of the IOL to increase spectacle independence;

estimating, by the control system, a phase delay based at least in part on measurements associated with subject-specific through-focus visual acuity; and

applying, by a pulsed laser system under control of the control system, a plurality of laser pulses to the selected areas of the IOL to change a refractive index of the selected areas, the laser pulses being configured to produce, by refractive index writing on the IOL, the change in phase profile of the IOL to increase spectacle independence, wherein the change includes compensation for the phase delay.

Assignments (1)

Continuity (3)

References Cited (400)