Granted Patent
B2
US 12,734,312 · App. 19/052,634 · Granted Sep 15, 2026
Droplet device actuation from inhalation sensing
Inventors:
Louis Thomas Germinario (Kingsport, TN); John H. Hebrank (Durham, NC); Charles Eric Hunter (Boone, NC); Jack C. Hunter (Boone, NC); Chengjie Li (Shenzhen City, CN); Christopher W. Maurer (Irvine, CA)
Assignee:
PNEUMA RESPIRATORY, INC.
A61M11/005A24F40/05A24F40/10A24F40/30A61B5/082A61B5/087A61M11/001A61M11/003A61M15/0003A61M15/001A61M15/002A61M15/0021A61M15/0065A61M15/0081A61M15/0085A61M15/0091A61M15/025A61M16/0051A61M16/0066A61M16/021A61M16/107A61M16/108A61M16/14A61M16/142B05B17/06G16H50/20G16H50/30A61B5/0816A61B5/091A61M11/002A61M15/00A61M15/0035A61M2016/0018A61M2016/0021A61M2016/0027A61M2016/0036A61M2016/0039A61M16/022A61M16/024A61M16/10A61M16/1075A61M2205/0233A61M2205/0238A61M2205/0294A61M2205/103A61M2205/27A61M2205/276A61M2205/33A61M2205/3306A61M2205/3313A61M2205/3327A61M2205/3331A61M2205/3334A61M2205/3553A61M2205/3569A61M2205/3584A61M2205/3592A61M2205/502A61M2205/505A61M2205/52A61M2205/583A61M2205/584A61M2205/587A61M2205/6018A61M2205/6072A61M2205/7536A61M2205/8206A61M2206/11A61M2207/00A61M2230/06A61M2230/205A61M2230/30A61M2230/40
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Abstract
An electronic droplet delivery device includes a housing including a mouthpiece located at an airflow exit side of the housing, a removable fluid reservoir, an aperture plate having a plurality of openings that receives fluid from the reservoir, an electronic actuator that oscillates the aperture plate to generate an ejected stream of droplets, and a sensor operably coupled to trigger the actuator to generate the ejected stream of droplets when a predetermined inhalation flow rate is detected by the sensor.
Claims (30)
1 . An electronically actuated droplet delivery device comprising:
a housing including a mouthpiece located at an airflow exit side of the housing;
a fluid reservoir disposed within or in fluid communication with the housing;
an electronically actuated aperture plate having a plurality of openings formed through its thickness wherein the aperture plate is in fluid communication with the fluid reservoir;
an electronic actuator operably coupled to vibrate the aperture plate at a frequency that generates an ejected stream of droplets;
a sensor operably coupled to trigger the electronic actuator to generate the ejected stream of droplets when a predetermined inhalation flow rate is detected by the sensor; and
a detector positioned at least at one of (a) between an airflow exit of the mouthpiece and the aperture plate and (b) across a face of the aperture plate, wherein the detector is configured to monitor a concentration of a compound in solution within an aerosol plume including the ejected stream of droplets based on optical absorbance specifically associated with the compound.
2 . The droplet delivery device of claim 1 , wherein the electronic actuator is a piezoelectric actuator and the detector includes an optical or image sensor.
3 . The droplet delivery device of claim 2 , wherein the fluid reservoir includes a medicine.
4 . The droplet delivery device of claim 3 , wherein the predetermined flow rate is about 10 SLM.
5 . The droplet delivery device of claim 3 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
6 . The droplet delivery device of claim 2 , wherein the fluid reservoir includes nicotine.
7 . The droplet delivery device of claim 6 , wherein the predetermined flow rate is about 10 SLM.
8 . The droplet delivery device of claim 6 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
9 . The droplet delivery device of claim 2 , wherein the fluid reservoir includes a chemical that is in marijuana.
10 . The droplet delivery device of claim 9 , wherein the predetermined flow rate is about 10 SLM.
11 . The droplet delivery device of claim 9 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
12 . The droplet delivery device of claim 2 , wherein the predetermined flow rate is about 10 SLM.
13 . The droplet delivery device of claim 2 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
14 . The droplet delivery device of claim 1 , wherein the fluid reservoir includes a medicine.
15 . The droplet delivery device of claim 14 , wherein the predetermined flow rate is about 10 SLM.
16 . The droplet delivery device of claim 14 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
17 . The droplet delivery device of claim 1 , wherein the fluid reservoir includes nicotine.
18 . The droplet delivery device of claim 17 , wherein the predetermined flow rate is about 10 SLM.
19 . The droplet delivery device of claim 17 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
20 . The droplet delivery device of claim 1 , wherein the fluid reservoir includes a chemical that is in marijuana.
21 . The droplet delivery device of claim 20 , wherein the predetermined flow rate is about 10 SLM.
22 . The droplet delivery device of claim 20 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
23 . The droplet delivery device of claim 1 , wherein the predetermined flow rate is about 10 SLM.
24 . The droplet delivery device of claim 1 , wherein the predetermined flow rate is a user's peak period of inhalation during an inhalation cycle.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 27, 2025
From: GERMINARIO, LOUIS THOMAS; HEBRANK, JOHN H.; HUNTER, CHARLES ERIC; HUNTER, JACK C.; LI, CHENGJIE; MAURER, CHRISTOPHER W.
To: PNEUMA RESPIRATORY, INC.
Reel/Frame 071553/0553 →
Continuity (14)
Provisional Application
62471929
· Mar 15, 2017
Provisional Application
62448796
· Jan 20, 2017
Provisional Application
62428696
· Dec 1, 2016
Provisional Application
62422932
· Nov 16, 2016
Provisional Application
62416026
· Nov 1, 2016
Provisional Application
62399091
· Sep 23, 2016
Provisional Application
62354437
· Jun 24, 2016
Provisional Application
62334076
· May 10, 2016
Provisional Application
62332352
· May 5, 2016
Provisional Application
62331328
· May 3, 2016
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