IP Library › Granted Patent US 12,734,344
Granted Patent B2
US 12,734,344 · App. 18/668,055 · Granted Sep 15, 2026

Methods and systems for draining cerebrospinal fluid into the venous system

Inventors: Carl Heilman (Wayland, MA); Adel M. Malek (Weston, MA); David A. Rezac (Westborough, MA); Timothy W. Robinson (Sandown, NH); Joseph Ting (Auburndale, MA)
Assignee: CereVasc, Inc.
A61M27/006A61B18/1477A61B34/20A61M25/0067A61M25/0108A61M25/0155A61M25/09A61M25/10A61M39/24A61B18/1492A61M2039/242A61M2039/2426A61M2210/06
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Quick Facts
Patent No.
US 12,734,344
App. No.
18/668,055
Granted
Sep 15, 2026
Kind
B2
Abstract

Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour.

Claims (16)

1 . A method for positioning an elongate medical device within a subarachnoid space (SAS) beneath dura and arachnoid tissue layers in a patient's cranium, the method comprising:

introducing a delivery catheter through a vascular access point of the patient, the delivery catheter having a sidewall opening in a distal portion of the delivery catheter;

navigating the delivery catheter through the patient's vascular system until the distal portion of the delivery catheter is positioned within a venous sinus of the patient;

expanding a stabilizing element coupled to, or incorporated within, the distal portion of the delivery catheter to position the side opening adjacent to a targeted location in a wall of the venous sinus;

advancing a tissue penetrating member out the side opening of the delivery catheter and through the sinus wall to thereby create an anastomosis between the venous sinus and the SAS; and

deploying the elongate medical device out the side opening of the delivery catheter and through the anastomosis so that a distal portion of the elongate medical device is positioned in the SAS.

2 . The method of claim 1 , wherein the tissue penetrating member comprises a stylet configured to pass-through the dura and arachnoid tissue layers while minimizing tearing of dura when penetrating therethrough.

3 . The method of claim 2 , wherein the tissue penetrating member comprises a beveled or Quincke tip configuration.

4 . The method of claim 1 , wherein the tissue penetrating member comprises a tissue penetrating distal tip of, or disposed on, the elongate medical device.

5 . The method of claim 1 , wherein the stabilizing element comprises an inflatable balloon.

6 . The method of claim 1 , wherein the elongate medical device comprises an implant.

7 . The method of claim 1 , wherein the delivery catheter comprises a lumen through which the tissue penetrating member and elongate medical device are delivered, and a deflection ramp disposed within the lumen and configured to deflect the respective tissue penetrating member and elongate medical device through the side wall opening.

8 . The method of claim 1 , the delivery catheter comprising one or more radiopaque markers located and dimensioned to indicate a trajectory of the tissue penetrating member when deployed out the side opening.

9 . The method of claim 1 , the tissue penetrating member comprising a penetration stop configured to limit a distance in which the tissue penetrating distal member may be advanced through the anastomosis.

10 . The method of claim 1 , wherein the venous sinus comprises an inferior petrosal sinus.

11 . The method of claim 1 , wherein the stabilizing element comprises a coil, a stent, or an expandable foam.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 28, 2024
From: HEILMAN, CARL; MALEK, ADEL M.; REZAC, DAVID A.; ROBINSON, TIMOTHY W.; TING, JOSEPH
To: CEREVASC, LLC
Reel/Frame 068428/0323 →
CHANGE OF NAME Recorded Aug 28, 2024
From: CEREVASC, LLC
To: CEREVASC, INC.
Reel/Frame 068807/0716 →
Continuity (13)
Continuation 16998606 · Aug 20, 2020
Continuation 15981118 · May 16, 2018
Continuation 15862120 · Jan 4, 2018
Continuation 15668657 · Aug 3, 2017
Continuation 15432818 · Feb 14, 2017
Continuation 15289790 · Oct 10, 2016
Continuation 15195139 · Jun 28, 2016
Continuation 15065766 · Mar 9, 2016
Division 14929066 · Oct 30, 2015
Provisional Application 62156152 · May 1, 2015
Provisional Application 62142895 · Apr 3, 2015
Provisional Application 62073766 · Oct 31, 2014
Related Publication 20240299714A1 · Sep 12, 2024
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