Occlusion device with sensing functionality
Systems and methods for delivering an implantable sensor assembly into a vascular structure. The sensor assembly is capable of detecting one or more physiological parameters of a patient and generating sensor data. The one or more physiological parameters may be indicative of blood flow through the vascular structure. The sensor assembly may wirelessly transmit the sensor data to a receiver.
1 . An implantable sensor system capable of being implanted within an intracranial saccular aneurysm of a patient, the sensor system comprising:
a sensor capable of detecting one or more physiological parameters of the patient and generating sensor data, wherein the sensor comprises a glucose sensor and the one or more physiological parameters comprises glucose in the blood of the patient; and
an antenna assembly in electrical communication with the sensor, the antenna assembly comprising a plurality of at least five antennae wrapped around the sensor and forming a spherical structure that encloses the sensor, the spherical structure configured to fit within the intracranial aneurysm and to anchor the system within the intracranial aneurysm, the antenna assembly configured to transmit sensor data related to the one or more physiological parameters of the patient to a receiver, the antenna assembly capable of being compressed for loading into a delivery system and expanded upon release from the delivery system.
2 . The implantable sensor system of claim 1 , further comprising a sealing layer to hermetically seal the sensor.
3 . The implantable sensor system of claim 1 , further comprising a dissolving membrane layer that dissolves when in contact with blood of the patient.
4 . The implantable sensor system of claim 1 , further comprising a power source for providing power to the sensor.
5 . The implantable sensor system of claim 1 , further comprising a supercapacitor to provide power to the sensor.
6 . The implantable sensor system of claim 1 , further comprising a memory device for storing sensor data.
7 . The implantable sensor system of claim 1 , further comprising a second sensor capable of detecting a different physiological parameter than glucose.
8 . The implantable sensor system of claim 1 , wherein the sensor further comprises a conductivity switch configured to detect a presence of fluid above a threshold amount.
9 . The implantable sensor system of claim 8 , wherein the conductivity switch comprises two spaced apart conductive pads.
10 . The implantable sensor system of claim 8 , wherein the glucose sensor is configured to operate only when fluid above the threshold amount is detected.
11 . A kit comprising:
the implantable sensor system of claim 1 ; and
a delivery system capable of releasing the implantable sensor assembly into an aneurysm of a patient in a vascular structure.
12 . A method of monitoring an aneurysm of a patient, the method comprising:
detecting one or more physiological parameters of the aneurysm using an implantable sensor system of claim 1 ; and
transmitting sensor data related to the one or more physiological parameters to a remote location.
13 . The method of claim 12 , further comprising occluding the aneurysm with an anchor structure.
14 . A method of implanting a sensor system into an aneurysm of a patient, the method comprising:
advancing a delivery system carrying the sensor system of claim 1 to an intracranial aneurysm of the patient; and
releasing the sensor system inside the intracranial aneurysm; whereupon the antenna assembly adopts a spherical structure configured to fit within the intracranial aneurysm and to anchor the sensor system within the intracranial aneurysm.
15 . An implantable sensor system capable of being implanted within an intracranial saccular aneurysm of a patient, the sensor system comprising:
a sensor capable of detecting one or more physiological parameters of a patient and generating sensor data, wherein the sensor comprises a glucose sensor and the one or more physiological parameters comprises glucose in the blood of the patient and a conductivity switch configured to detect a presence of fluid above a threshold amount;
an antenna assembly in electrical communication with the sensor, the antenna assembly comprising a plurality of at least five antennae wrapped around the sensor and forming a spherical structure that encloses the sensor, the spherical structure configured to fit within the intracranial aneurysm and to anchor the system within the intracranial aneurysm, the antenna assembly configured to transmit sensor data related to the one or more physiological parameters of the patient to a receiver, the antenna assembly capable of being compressed for loading into a delivery system and expanded upon release from the delivery system; and
wherein the implantable sensor system is configured to fit within an intracranial aneurysm of the patient, and the system comprises a radiopaque marker selected to allow identification of the location of the system within the intracranial space of the patient.
16 . A kit comprising:
the implantable sensor system of claim 15 ; and
a delivery system comprising a shaft having a shaft wall defining a lumen, and a retention wire extending along the shaft partially within the lumen and partially outside the lumen, wherein portions of the retention wire outside the lumen retain the anchor structure in place relative to the shaft, the retention wire capable of being moved relative to the shaft to thereby release the implantable sensor system from the shaft into the aneurysm.