IP Library › Granted Patent US 12,746,156
Granted Patent B2
US 12,746,156 · App. 18/947,691 · Granted Sep 29, 2026

Ophthalmic knife and methods of use

Inventors: Malik Y. Kahook (Denver, CO); Khalid Mansour (Eastvale, CA); Suhail Abdullah (Fontana, CA); Eric Porteous (Corona, CA); Vijay R. Balan (Torrance, CA)
Assignees: THE REGENTS OF THE UNIVERSITY OF COLORADO; NEW WORLD MEDICAL, INC.
A61F9/0133A61B17/320068A61F9/00745A61F9/00781A61B2017/00867A61B2017/320082A61B17/3211A61B2217/005A61F9/00736
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Quick Facts
Patent No.
US 12,746,156
App. No.
18/947,691
Granted
Sep 29, 2026
Kind
B2
Abstract

An ophthalmic knife for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques is provided. The ophthalmic knife includes a shaft, a first platform connected to an end of the shaft and extending at an angle from a longitudinal axis of the shaft and a second platform connected to the shaft adjacent to the first platform. The first platform includes a first top surface extending from a first tip and a first bottom surface opposing the first top surface, and the second platform includes a second top surface extending from a second tip, and a second bottom surface opposing the second top surface. The first platform severs trabecular meshwork in a human eye as the trabecular meshwork advances over the first top surface of the first platform and the second bottom surface of the second platform engages but does not sever the trabecular meshwork.

Claims (48)

1 . An ophthalmic knife, comprising:

a shaft;

a first platform connected to an end of the shaft and extending at an angle from a longitudinal axis of the shaft, the first platform comprising:

a first top surface extending from a first tip; and

a first bottom surface opposing the first top surface; and

a second platform connected to the shaft adjacent to the first platform, the second platform comprising:

a second top surface extending from a second tip; and

a second bottom surface opposing the second top surface,

wherein the first platform is configured to sever trabecular meshwork in a human eye as the trabecular meshwork advances over the first top surface of the first platform, and the second bottom surface of the second platform is configured to engage but not sever the trabecular meshwork,

wherein the first top surface of the first platform comprises a planar ramp extending from a tip side to a back side of the first platform opposite the tip side,

and wherein a recess extends from the planar ramp toward the back side of the first platform, at least a portion of the recess disposed above an entirety of a top surface of the planar ramp.

2 . The ophthalmic knife of claim 1 , wherein the first platform and the second platform are radially offset.

3 . The ophthalmic knife of claim 1 , wherein the first platform radially projects from the shaft in a first direction and the second platform radially projects from the shaft in a second direction which is opposite the first direction.

4 . The ophthalmic knife of claim 1 , wherein the planar ramp extends at an obtuse angle from the shaft.

5 . The ophthalmic knife of claim 1 , wherein when the first platform is advanced between the trabecular meshwork and an outer wall of Schlemm's canal, a portion of the trabecular meshwork on the planar ramp is elevated away from the outer wall of Schlemm's canal without cutting the portion of the trabecular meshwork from surrounding portions of the trabecular meshwork and the portion of the trabecular meshwork is guided toward the shaft.

6 . The ophthalmic knife of claim 1 , wherein a portion of the trabecular meshwork is received in the recess when the platform is advanced between the trabecular meshwork and an outer wall of Schlemm's canal.

7 . The ophthalmic knife of claim 1 , where a bottom surface of the recess is planar.

8 . The ophthalmic knife of claim 1 , wherein the first platform comprises first and second sides extending from the first bottom surface to the first top surface and from the first tip laterally toward the shaft.

9 . The ophthalmic knife of claim 8 , wherein the first and second sides define cutting blades.

10 . The ophthalmic knife of claim 8 , wherein the second platform comprises third and fourth sides extending from the second bottom surface to the second top surface.

11 . The ophthalmic knife of claim 8 , wherein the first and second sides are angled and a width between the first and second angled sides increases toward a shaft side of the first platform.

12 . The ophthalmic knife of claim 11 , wherein first and second lateral sides are disposed between the first and second angled sides and the shaft side of the first platform, the first and second lateral sides being substantially parallel.

13 . The ophthalmic knife of claim 1 , wherein the first tip is configured to pierce the trabecular meshwork.

14 . The ophthalmic knife of claim 1 , wherein the second platform is configured such that the second bottom surface of the second platform is disposed on a top surface of the trabecular meshwork when the first platform is in the trabecular meshwork.

15 . The ophthalmic knife of claim 1 , wherein when the first top surface is advanced between the trabecular meshwork and an outer wall of Schlemm's canal, a portion of the trabecular meshwork on the first top surface is elevated away from the outer wall of Schlemm's canal without cutting the portion of the trabecular meshwork and the portion is guided toward the shaft.

16 . The ophthalmic knife of claim 1 , wherein the first platform further comprises first and second lateral elements extending above the first top surface.

17 . The ophthalmic knife of claim 16 , where the first lateral element defines a first cutting blade and the second lateral element defines a second cutting blade.

18 . The ophthalmic knife of claim 16 , wherein the first and second lateral elements are linear.

19 . An ophthalmic knife, comprising:

a shaft;

a first platform connected to an end of the shaft and extending at an angle from a longitudinal axis of the shaft, the first platform comprising:

a first top surface extending from a first tip;

a first bottom surface opposing the first top surface; and

first and second sides extending from the first bottom surface to the first top surface and from the first tip laterally toward the shaft, wherein the first and second sides define cutting blades; and

a second platform connected to the shaft adjacent to the first platform, the second platform comprising:

a second top surface extending from a second tip; and

a second bottom surface opposing the second top surface,

wherein the first platform is configured to sever trabecular meshwork in a human eye as the trabecular meshwork advances over the first top surface of the first platform, and the second bottom surface of the second platform is configured to engage but not sever the trabecular meshwork.

20 . An ophthalmic knife, comprising:

a shaft;

a first platform connected to an end of the shaft and extending at an angle from a longitudinal axis of the shaft, the first platform comprising:

a first top surface extending from a first tip;

a first bottom surface opposing the first top surface;

first and second lateral elements extending above the first top surface, the first lateral element defining a first cutting blade and the second lateral element defining a second cutting blade; and

a second platform connected to the shaft adjacent to the first platform, the second platform comprising:

a second top surface extending from a second tip; and

a second bottom surface opposing the second top surface,

wherein the first platform is configured to sever trabecular meshwork in a human eye as the trabecular meshwork advances over the first top surface of the first platform, and the second bottom surface of the second platform is configured to engage but not sever the trabecular meshwork.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 15, 2024
From: KAHOOK, MALIK Y.
To: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Reel/Frame 069385/0304 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 15, 2024
From: MANSOUR, KHALID; ABDULLAH, SUHAIL; PORTEOUS, ERIC; BALAN, VIJAY R.
To: NEW WORLD MEDICAL INC.
Reel/Frame 069385/0309 →
Continuity (9)
Continuation 18237684 · Aug 24, 2023
Continuation 18070218 · Nov 28, 2022
Continuation 17741170 · May 10, 2022
Continuation 16996736 · Aug 18, 2020
Continuation 16703666 · Dec 4, 2019
Continuation In Part 16015078 · Jun 21, 2018
Continuation 15389328 · Dec 22, 2016
Provisional Application 62387351 · Dec 23, 2015
Related Publication 20250064643A1 · Feb 27, 2025
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