IP Library Granted Patent US 10,398,667
Granted Patent B2
US 10,398,667 · App. 15/872,436 · Granted Sep 3, 2019

Methods of treating hair related conditions

Inventors: Sergio Baroni (Villa d'adda, IT); Salvatore Bellinvia (Mendrisio, CH); Francesca Viti (Salorino, CH)
Assignee: Nogra Pharma Limited
A61K31/196A61K8/42A61Q5/00A61Q7/00A61Q19/02A61Q19/06A61Q19/08C07C233/54C07C235/38C07D307/79C07D319/08A61K2800/78
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Quick Facts
Patent No.
US 10,398,667
App. No.
15/872,436
Granted
Sep 3, 2019
Kind
B2
Abstract

Disclosed herein are methods for treating hair related disorders, including compounds that may be specific or modulate PPAR receptors.

Claims (22)

1. A method for modulating hair growth in a human subject in need thereof, the method comprising administering topically to the human subject a therapeutically effective amount of a pharmaceutically and/or cosmetically acceptable composition comprising:

N-acetyl-(S)-3-(4-aminophenyl)-2-methoxypropionic acid, or a pharmaceutically acceptable salt or an N-oxide thereof; and

an excipient.

2. The method of claim 1 , wherein the composition further comprises a hair stimulating agent.

3. The method of claim 1 , wherein the method further comprises administering a hair stimulating agent.

4. A method for treating or ameliorating limited hair growth, short hair growth, or hair loss in a human subject in need thereof, the method comprising administering topically to the human subject a therapeutically effective amount of a pharmaceutically and/or cosmetically acceptable composition comprising:

N-acetyl-(S)-3-(4-aminophenyl)-2-methoxypropionic acid, or a pharmaceutically acceptable salt or an N-oxide thereof; and

an excipient.

5. The method of claim 4 , wherein the composition further comprises a hair stimulating agent.

6. The method of claim 4 , wherein the method further comprises administering a hair stimulating agent.

7. A method for treating or ameliorating alopecia in a human subject in need thereof, the method comprising administering topically to the human subject a therapeutically effective amount of a pharmaceutically and/or cosmetically acceptable composition comprising:

N-acetyl-(S)-3-(4-aminophenyl)-2-methoxypropionic acid, or a pharmaceutically acceptable salt or an N-oxide thereof; and

an excipient.

8. The method of claim 7 , wherein the alopecia is anagen alopecia.

9. The method of claim 7 , wherein the alopecia is telogen alopecia.

10. The method of claim 7 , wherein the alopecia is alopecia areata.

11. The method of claim 8 , wherein the composition further comprises a hair stimulating agent.

12. The method of claim 9 , wherein the composition further comprises a hair stimulating agent.

13. The method of claim 10 , wherein the composition further comprises a hair stimulating agent.

14. The method of claim 8 , wherein the method further comprises administering a hair stimulating agent.

15. The method of claim 9 , wherein the method further comprises administering a hair stimulating agent.

16. The method of claim 10 , wherein the method further comprises administering a hair stimulating agent.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 13, 2018
From: BARONI, SERGIO; BELLINVIA, SALVATORE; VITI, FRANCESCA
To: GIULIANI INTERNATIONAL, LTD.
Reel/Frame 047765/0491 →
CHANGE OF NAME Recorded Dec 13, 2018
From: GIULIANI INTERNATIONAL LIMITED
To: NOGRA PHARMA LIMITED
Reel/Frame 047826/0387 →
Priority Claims (1)
EP 09425056 · Feb 16, 2009 · regional
Continuity (6)
Continuation 14969939 · Dec 15, 2015
Continuation 14314738 · Jun 25, 2014
Continuation 13201790
Provisional Application 61287461 · Dec 17, 2009
Provisional Application 61179062 · May 18, 2009
Related Publication 20180369178A1 · Dec 27, 2018
Cited By (2)
US 12,291,494 US 12,509,416