IP Library Granted Patent US 12,390,117
Granted Patent B2
US 12,390,117 · App. 17/711,974 · Granted Aug 19, 2025

Optical sensor module for speckleplethysmography (SPG) and photoplethysmography (PPG)

Inventors: Kate LeeAnn Bechtel (Pleasant Hill, CA); James McMillan (Santa Monica, CA); Farzaneh Afshinmanesh (Pasadena, CA); Cody Dunn (Costa Mesa, CA)
Assignee: Rockley Photonics Limited
A61B5/02433A61B5/02438A61B5/0295A61B5/681
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,390,117
App. No.
17/711,974
Granted
Aug 19, 2025
Kind
B2
Abstract

An optical sensor module for measuring both speckleplethysmography (SPG) and photoplethysmography (PPG) signals at human or animal tissue, the optical sensor module comprising:a first light source, for illuminating the tissue for use with SPG measurements, the first light source comprising a laser; a second light source, for illuminating the tissue for use with PPG measurements; and one or more optical sensor(s) for receiving light from the illuminated tissue.

Claims (26)

1. A wearable device comprising an optical sensor module, the optical sensor module comprising:

a light source comprising a laser, the light source being configured to selectively apply speckle mitigation techniques to light generated by the laser and to illuminate tissue;

an image sensor configured to selectively receive, through the tissue, a first light signal from the light source when the light source does not apply the speckle mitigation techniques;

a photodiode configured to selectively receive, through the tissue, a second light signal from the light source when the light source does apply the speckle mitigation techniques; and

a processor configured to process first data, corresponding to the first light signal, to generate a speckleplethysmography (SPG) measurement, and to process second data, corresponding to the second light signal, to generate a photoplethysmography (PPG) measurement.

2. The wearable device of claim 1 , wherein the image sensor is configured to carry out in-pixel DC subtraction.

3. The wearable device of claim 1 , wherein the image sensor is configured to carry out a pixel block statistics calculation or a pixel array statistics calculation.

4. The wearable device of claim 1 , wherein the light source is configured to apply the speckle mitigation techniques via a deformable mirror, an optical phase array, raster scanning, angle scanning, wavelength scanning, wavelength broadening, or any combination thereof.

5. The wearable device of claim 1 , including a wrist strap, the optical sensor module being coupled to the wrist strap.

6. A wearable device comprising an optical sensor module, the optical sensor module comprising:

a light source comprising a laser and being configured to illuminate tissue;

one or more optical sensors configured to respectively receive, through the tissue, one or more light signals from the light source, the one or more optical sensors including an image sensor configured to carry out in-pixel DC light subtraction to subtract out a non-pulsatile component of a first light signal of the one or more light signals; and

a processor configured to process data to generate a speckleplethysmography (SPG) measurement and a photoplethysmography (PPG) measurement, the data corresponding to the one or more light signals.

7. The wearable device of claim 6 , wherein the image sensor is configured to receive, through the tissue, the one or more light signals from the light source.

8. The wearable device of claim 6 , wherein the light source is configured to selectively apply speckle mitigation techniques to light generated by the laser.

9. The wearable device of claim 8 , wherein the one or more optical sensors are configured to selectively receive the one or more light signals.

10. The wearable device of claim 6 , the optical sensor module comprising:

a coherent optical output configured to illuminate tissue with coherent light; and

an incoherent optical output configured to illuminate the tissue with incoherent light,

wherein the laser is configured to generate light at the coherent optical output, and the optical sensor module is configured to apply one or more speckle mitigation techniques to light generated by the laser to provide light at the incoherent optical output,

wherein the image sensor is configured to receive, through the tissue, the first light signal from the coherent optical output and a second light signal from the incoherent optical output, and

wherein the optical sensor module is configured to process first data and second data to respectively generate (SPG) the SPG measurement and the PPG measurement, the first data corresponding to the first light signal, and the second data corresponding to the second light signal.

11. The wearable device of claim 10 , wherein the image sensor includes a CMOS image sensor.

12. The wearable device of claim 10 , wherein the image sensor includes an event-based camera.

13. The wearable device of claim 10 , wherein

the image sensor is configured to carry out a pixel block statistics calculation or a pixel array statistics calculation.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 25, 2024
From: BECHTEL, KATE LEEANN; MCMILLAN, JAMES; AFSHINMANESH, FARZANEH; DUNN, CODY
To: ROCKLEY PHOTONICS LIMITED
Reel/Frame 069027/0696 →
RELEASE OF PATENT SECURITY INTEREST - SUPER SENIOR INDENTURE - REEL/FRAME 061768/0082 Recorded Mar 19, 2023
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
To: ROCKLEY PHOTONICS LIMITED
Reel/Frame 063264/0416 →
RELEASE OF SECURITY INTEREST - REEL/FRAME 061604/0025 Recorded Mar 19, 2023
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
To: ROCKLEY PHOTONICS LIMITED
Reel/Frame 063287/0812 →
SECURITY INTEREST Recorded Mar 19, 2023
From: ROCKLEY PHOTONICS LIMITED
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 063287/0879 →
SECURITY INTEREST - SUPER SENIOR INDENTURE Recorded Oct 25, 2022
From: ROCKLEY PHOTONICS LIMITED
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 061768/0082 →
SECURITY INTEREST Recorded Oct 4, 2022
From: ROCKLEY PHOTONICS LIMITED
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 061604/0025 →
Continuity (2)
Provisional Application 63279932 · Nov 16, 2021
Related Publication 20230148885A1 · May 18, 2023
References Cited (297)
US 5243983A · Tarr et al. · 1993 [cited by applicant]
US 5830132A · Robinson · 1998 [cited by applicant]
US 6246892B1 · Chance · 2001 [cited by applicant]
US 6560478B1 · Alfano et al. · 2003 [cited by applicant]
US 6919549B2 · Bamji et al. · 2005 [cited by applicant]
US 7035679B2 · Addison et al. · 2006 [cited by applicant]
US 7113817B1 · Winchester, Jr. et al. · 2006 [cited by applicant]
US 7250317B2 · Heideman · 2007 [cited by applicant]
US 7295783B2 · Singh et al. · 2007 [cited by applicant]
US 7375812B2 · Atia et al. · 2008 [cited by applicant]
US 7505128B2 · Zribi et al. · 2009 [cited by applicant]
US 7761126B2 · Gardner et al. · 2010 [cited by applicant]
US 7865225B2 · Kaltschmidt et al. · 2011 [cited by applicant]
US 7922664B2 · Elliott · 2011 [cited by applicant]
US 7925056B2 · Presura et al. · 2011 [cited by applicant]
US 8237927B1 · Reeve et al. · 2012 [cited by applicant]
US 8277384B2 · Fine · 2012 [cited by applicant]
US 8313439B2 · McCombie et al. · 2012 [cited by applicant]
US 8343062B2 · Fortin et al. · 2013 [cited by applicant]
US 8343063B2 · Borgos · 2013 [cited by applicant]
US 8376955B2 · Baker, Jr. · 2013 [cited by applicant]
US 8398556B2 · Sethi et al. · 2013 [cited by applicant]
US 8868149B2 · Eisen et al. · 2014 [cited by applicant]
US 8920332B2 · Hong et al. · 2014 [cited by applicant]
US 8923942B2 · Bernreuter · 2014 [cited by applicant]
US 8945017B2 · Venkatraman et al. · 2015 [cited by applicant]
US 8948832B2 · Hong et al. · 2015 [cited by applicant]
US 8956303B2 · Hong et al. · 2015 [cited by applicant]
US 8998815B2 · Venkatraman et al. · 2015 [cited by applicant]
US 9005129B2 · Venkatraman et al. · 2015 [cited by applicant]
US 9113794B2 · Hong et al. · 2015 [cited by applicant]
US 9113795B2 · Hong et al. · 2015 [cited by applicant]
US 9149216B1 · Eisen et al. · 2015 [cited by applicant]
US 9155480B2 · Thakor et al. · 2015 [cited by applicant]
US 9226673B2 · Ferguson, Jr. et al. · 2016 [cited by applicant]
US 9237855B2 · Hong et al. · 2016 [cited by applicant]
US 9307917B2 · Hong et al. · 2016 [cited by applicant]
US 9494567B2 · Islam · 2016 [cited by applicant]
US 9687162B2 · Vetter et al. · 2017 [cited by applicant]
US 9704050B2 · Lee et al. · 2017 [cited by applicant]
US 9730622B2 · Eisen et al. · 2017 [cited by applicant]
US 9772280B2 · Cerussi et al. · 2017 [cited by applicant]
US 9804027B2 · Fish et al. · 2017 [cited by applicant]
US 9846126B2 · Gunn, III et al. · 2017 [cited by applicant]
US 9848787B2 · White et al. · 2017 [cited by applicant]
US 9877681B2 · Silverman · 2018 [cited by applicant]
US 9931040B2 · Homyk et al. · 2018 [cited by applicant]
US 9970955B1 · Homyk et al. · 2018 [cited by applicant]
US 10004406B2 · Yuen et al. · 2018 [cited by applicant]
US 10058256B2 · Chen et al. · 2018 [cited by applicant]
US 10178959B1 · Homyk et al. · 2019 [cited by applicant]
US 10178973B2 · Venkatraman et al. · 2019 [cited by applicant]
US 10194808B1 · Thompson et al. · 2019 [cited by applicant]
US 10206576B2 · Shcherbakov et al. · 2019 [cited by applicant]
US 10215698B2 · Han et al. · 2019 [cited by applicant]
US 10241033B2 · Uematsu et al. · 2019 [cited by applicant]
US 10271740B2 · Ward et al. · 2019 [cited by applicant]
US 10314532B2 · Ward et al. · 2019 [cited by applicant]
US 10326035B2 · Lu et al. · 2019 [cited by applicant]
US 10326036B2 · Sweeney et al. · 2019 [cited by applicant]
US 10349847B2 · Kwon et al. · 2019 [cited by applicant]
US 10352768B2 · Simpkin et al. · 2019 [cited by applicant]
US 10357165B2 · Yoon · 2019 [cited by applicant]
US 10422693B2 · Fish et al. · 2019 [cited by applicant]
US 10451537B2 · Nakaji · 2019 [cited by applicant]
US 10463286B2 · Schenkman et al. · 2019 [cited by applicant]
US 10492684B2 · Khachaturian et al. · 2019 [cited by applicant]
US 10506926B2 · Khachaturian et al. · 2019 [cited by applicant]
US 10506955B2 · Tholl et al. · 2019 [cited by applicant]
US 10568527B2 · Yoon et al. · 2020 [cited by applicant]
US 10588519B2 · Yuen et al. · 2020 [cited by applicant]
US 10602987B2 · Khachaturian et al. · 2020 [cited by applicant]
US 10627849B1 · Scofield et al. · 2020 [cited by applicant]
US 10641962B2 · Nykänen et al. · 2020 [cited by applicant]
US 10643903B2 · Drake et al. · 2020 [cited by applicant]
US 10667688B2 · Khachaturian et al. · 2020 [cited by applicant]
US 10677989B2 · Abediasl et al. · 2020 [cited by applicant]
US 10681259B2 · Ichiki et al. · 2020 [cited by applicant]
US 10681283B2 · Nakashima et al. · 2020 [cited by applicant]
US 10694997B2 · Kim et al. · 2020 [cited by applicant]
US 10718668B2 · Gu et al. · 2020 [cited by applicant]
US 10722177B2 · Homyk et al. · 2020 [cited by applicant]
US 10739256B1 · Rickman et al. · 2020 [cited by applicant]
US 10750956B2 · Zalevsky et al. · 2020 [cited by applicant]
US 10775239B2 · Lee et al. · 2020 [cited by applicant]
US 10813597B2 · Rice et al. · 2020 [cited by applicant]
US 10820858B2 · Yoon et al. · 2020 [cited by applicant]
US 10842422B2 · Yu et al. · 2020 [cited by applicant]
US 10871503B1 · Homyk et al. · 2020 [cited by applicant]
US 10966616B2 · De Morree et al. · 2021 [cited by applicant]
US 10973422B2 · Pantelopoulos et al. · 2021 [cited by applicant]
US 11022751B2 · Bauters et al. · 2021 [cited by applicant]
US 11045103B2 · Shchekin et al. · 2021 [cited by applicant]
US 11079364B2 · Leger et al. · 2021 [cited by applicant]
US 11096601B2 · Hong et al. · 2021 [cited by applicant]
US 11096608B2 · Van Dorpe et al. · 2021 [cited by applicant]
US 11129544B2 · Zalevsky et al. · 2021 [cited by applicant]
US 11202582B2 · Verkruijsse et al. · 2021 [cited by applicant]
US 11213217B2 · Han et al. · 2022 [cited by applicant]
US 11278220B2 · Tucker et al. · 2022 [cited by applicant]
US 11298035B2 · Huijbregts et al. · 2022 [cited by applicant]
US 11369275B2 · Song et al. · 2022 [cited by applicant]
US 11445922B2 · Naima · 2022 [cited by applicant]
US 11553851B2 · Kim et al. · 2023 [cited by applicant]
US 11583185B2 · Homyk et al. · 2023 [cited by applicant]
US 11666238B2 · Rege et al. · 2023 [cited by applicant]
US 11666277B2 · Yoon et al. · 2023 [cited by applicant]
US 11684281B2 · Pantelopoulos et al. · 2023 [cited by applicant]
US 11690513B2 · Hu et al. · 2023 [cited by applicant]
US 11696693B2 · Wong · 2023 [cited by applicant]
US 11709120B2 · Rice et al. · 2023 [cited by applicant]
US 11744491B2 · Dunn et al. · 2023 [cited by applicant]
US 11751811B2 · Sun et al. · 2023 [cited by applicant]
US 11759116B2 · White et al. · 2023 [cited by applicant]
US 11759121B2 · Mccann et al. · 2023 [cited by applicant]
US 11771343B2 · Sacha · 2023 [cited by applicant]
US 11800990B2 · White et al. · 2023 [cited by applicant]
US 11857301B1 · Homyk et al. · 2024 [cited by applicant]
US 11883134B2 · Leabman · 2024 [cited by applicant]
US 11890081B2 · Jang · 2024 [cited by applicant]
US 11980451B2 · Albert · 2024 [cited by applicant]
US 20020068859A1 · Knopp · 2002 [cited by examiner]
US 20050249509A1 · Nagarajan et al. · 2005 [cited by applicant]
US 20060124829A1 · Song et al. · 2006 [cited by applicant]
US 20060204175A1 · Laurent-Lund et al. · 2006 [cited by applicant]
US 20080204752A1 · Dorvee et al. · 2008 [cited by applicant]
US 20080220512A1 · Koh et al. · 2008 [cited by applicant]
US 20080316567A1 · Grasser et al. · 2008 [cited by applicant]
US 20110054277A1 · Pinter et al. · 2011 [cited by applicant]
US 20110082355A1 · Eisen et al. · 2011 [cited by applicant]
US 20110196244A1 · Ribas Ripoll et al. · 2011 [cited by applicant]
US 20120130215A1 · Fine et al. · 2012 [cited by applicant]
US 20130131475A1 · Eisen et al. · 2013 [cited by applicant]
US 20130190630A1 · Borgos · 2013 [cited by applicant]
US 20140094666A1 · Fine · 2014 [cited by applicant]
US 20140200423A1 · Eisen et al. · 2014 [cited by applicant]
US 20140316286A1 · Addison et al. · 2014 [cited by applicant]
US 20140376001A1 · Swanson · 2014 [cited by applicant]
US 20150157224A1 · Carmon et al. · 2015 [cited by applicant]
US 20150196251A1 · Outwater et al. · 2015 [cited by applicant]
US 20150201854A1 · Hong et al. · 2015 [cited by applicant]
US 20160066790A1 · Shcherbakov et al. · 2016 [cited by applicant]
US 20160106327A1 · Yoon et al. · 2016 [cited by applicant]
US 20160157736A1 · Huang et al. · 2016 [cited by applicant]
US 20160161685A1 · Xu et al. · 2016 [cited by applicant]
US 20160266337A1 · Feng · 2016 [cited by applicant]
US 20160278676A1 · Eisen et al. · 2016 [cited by applicant]
US 20160282265A1 · Su et al. · 2016 [cited by applicant]
US 20160287107A1 · Szabados et al. · 2016 [cited by applicant]
US 20170014037A1 · Coppola et al. · 2017 [cited by applicant]
US 20170065184A1 · Barak · 2017 [cited by applicant]
US 20170108439A1 · Stievater et al. · 2017 [cited by applicant]
US 20170138789A1 · Ivanov · 2017 [cited by applicant]
US 20170231513A1 · Presura · 2017 [cited by examiner]
US 20170315292A1 · Mullen et al. · 2017 [cited by applicant]
US 20180045566A1 · Fish et al. · 2018 [cited by applicant]
US 20180064399A1 · Buettgen · 2018 [cited by examiner]
US 20180110423A1 · Presura et al. · 2018 [cited by applicant]
US 20180160913A1 · Fine · 2018 [cited by applicant]
US 20180238794A1 · Kangas et al. · 2018 [cited by applicant]
US 20180263519A1 · Gu · 2018 [cited by applicant]
US 20180283950A1 · Ge et al. · 2018 [cited by applicant]
US 20180296168A1 · Rice et al. · 2018 [cited by applicant]
US 20190005351A1 · Zhou · 2019 [cited by examiner]
US 20190046056A1 · Khachaturian et al. · 2019 [cited by applicant]
US 20190053721A1 · Boas et al. · 2019 [cited by applicant]
US 20190094009A1 · Aizawa et al. · 2019 [cited by applicant]
US 20190167118A1 · Vilenskii et al. · 2019 [cited by applicant]
US 20190175030A1 · Verkruijsse et al. · 2019 [cited by applicant]
US 20190336006A1 · Horstmeyer et al. · 2019 [cited by applicant]
US 20190343442A1 · Aung et al. · 2019 [cited by applicant]
US 20190343456A1 · Kahlert et al. · 2019 [cited by applicant]
US 20190387972A1 · Hu et al. · 2019 [cited by applicant]
US 20190391243A1 · Nicolaescu · 2019 [cited by applicant]
US 20190391702A1 · Jo et al. · 2019 [cited by applicant]
US 20200003619A1 · Hu et al. · 2020 [cited by applicant]
US 20200069225A1 · Vizbaras et al. · 2020 [cited by applicant]
US 20200158548A1 · Rice et al. · 2020 [cited by applicant]
US 20200196874A1 · Rozental et al. · 2020 [cited by applicant]
US 20200214602A1 · Narumi et al. · 2020 [cited by applicant]
US 20200359948A1 · Dunn et al. · 2020 [cited by applicant]
US 20200397351A1 · Miyata · 2020 [cited by applicant]
US 20210000385A1 · Warren et al. · 2021 [cited by applicant]
US 20210022623A1 · Rice · 2021 [cited by examiner]
US 20210028602A1 · Cao et al. · 2021 [cited by applicant]
US 20210267471A1 · Bonomi et al. · 2021 [cited by applicant]
US 20210386310A1 · Hong et al. · 2021 [cited by applicant]
US 20220015649A1 · Ikuta et al. · 2022 [cited by applicant]
US 20220019861A1 · Durr et al. · 2022 [cited by applicant]
US 20220039679A1 · Califa et al. · 2022 [cited by applicant]
US 20220265158A1 · Tokura · 2022 [cited by applicant]
US 20220370010A1 · Zilkie et al. · 2022 [cited by applicant]
US 20220413143A1 · Parsa et al. · 2022 [cited by applicant]
US 20230003938A1 · Zilkie et al. · 2023 [cited by applicant]
US 20230039055A1 · Gardner et al. · 2023 [cited by applicant]
US 20230087295A1 · Dunn et al. · 2023 [cited by applicant]
US 20230148885A1 · Bechtel et al. · 2023 [cited by applicant]
US 20230148886A1 · Bechtel et al. · 2023 [cited by applicant]
US 20230277075A1 · Pantelopoulos et al. · 2023 [cited by applicant]
US 20230320598A1 · Khine et al. · 2023 [cited by applicant]
US 20230347029A1 · Corso et al. · 2023 [cited by applicant]
US 20230397818A1 · Newhouse et al. · 2023 [cited by applicant]
US 20230401747A1 · Dunn et al. · 2023 [cited by applicant]
US 20240041342A1 · Lai et al. · 2024 [cited by applicant]
US 20240074667A1 · Rick et al. · 2024 [cited by applicant]
US 20240108289A1 · Bechtel et al. · 2024 [cited by applicant]
US 20240115212A1 · Jang · 2024 [cited by applicant]
US 20240156355A1 · O'Brien et al. · 2024 [cited by applicant]
CN 108709847A · 2018 [cited by applicant]
CN 110301896B · 2019 [cited by applicant]
CN 211094079U · 2020 [cited by applicant]
CN 211131004U · 2020 [cited by applicant]
EP 3002568A1 · 2016 [cited by applicant]
EP 2395958B1 · 2017 [cited by applicant]
EP 3384841A1 · 2018 [cited by applicant]
EP 3558119B1 · 2020 [cited by applicant]
EP 3886686 · 2021 [cited by applicant]
WO WO2018029123A1 · 2018 [cited by applicant]
WO WO2019149815A1 · 2019 [cited by applicant]
WO WO2019233903A1 · 2019 [cited by applicant]
WO WO2020030641A1 · 2020 [cited by applicant]
WO WO2020114989A1 · 2020 [cited by applicant]
WO WO2021058338A1 · 2021 [cited by applicant]
WO WO2021094473A1 · 2021 [cited by applicant]
WO WO2021116766A1 · 2021 [cited by applicant]
WO WO2021116766A8 · 2021 [cited by applicant]
WO WO2023245149A2 · 2023 [cited by applicant]
WO WO2024052289A1 · 2024 [cited by applicant]
Akram, M. N. et al., “Laser speckle reduction due to spatial and angular diversity introduced by fast scanning micromirror”, Applied Optics, Jun. 4, 2010, pp. 3297-3304, vol. 49, No. 17, Optical Society of America. [cited by applicant]
Baek, H. J. et al., “The Effect of Optical Crosstalk on Accuracy of Reflectance-Type Pulse Oximeter for Mobile Healthcare”, Journal of Healthcare Engineering, Oct. 21, 2018, 9 pages, vol. 2018, Article ID 3521738, Hinda… [cited by applicant]
Baets, R. et al., “Spectroscopy-on-chip applications of silicon photonics”, Proc. Of SPIE, 2013, pp. 86270I-1 through 86270I-10, vol. 8627, SPIE. [cited by applicant]
Berger, A. J. et al., “Feasibility of measuring blood glucose concentration by near-infrared Raman spectroscopy”, Spectrochimica Acta Part A, 1997, pp. 287-292, Elsevier Science B.V. [cited by applicant]
Bi, R. et al., “A speckle-based method for fast blood flow measurement in deep tissue”, Proceedings of SPIE, Optical Biopsy XIX: Toward Real-Time Spectroscopic Imaging and Diagnosis, Mar. 5, 2021, pp. 1163606-1 through … [cited by applicant]
Biswas, A. et al., “Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser”, Biomedical Optics Express, Oct. 4, 2021, pp. 6686-6700, vol. 12, No. 11, Optical Society of America. [cited by applicant]
Brouckaert, J. et al., “Silicon-on-Insulator Microspectrometer”, Proceedings Symposium IEEE/LEOS Benelux Chapter, 2008, pp. 7-10, IEEE. [cited by applicant]
Cole, D. B. et al., “Integrated heterodyne interferometer with on-chip modulators and detectors”, Optics Letters, Jun. 25, 2015, pp. 3097-3100, vol. 40, No. 13, Optical Society of America. [cited by applicant]
Epping, J. P. et al., “High power, tunable, narrow linewidth dual gain hybrid laser”, Laser Congress, Oct. 3, 2019, pp. 1-2. [cited by applicant]
Fu, D. et al., “In Vivo Metabolic Fingerprinting of Neutral Lipids with Hyperspectral Stimulated Raman Scattering Microscopy”, Journal of the American Chemical Society, May 28, 2014, pp. 8820-8828, American Chemical Soc… [cited by applicant]
Fukui, T. et al., “Single-Pixel Imaging Using Multimode Fiber and Silicon Photonic Phased Array”, Journal of Lightwave Technology, Jul. 14, 2020, pp. 839-844, vol. 39, No. 3, IEEE. [cited by applicant]
Gottschling, K. et al., “Molecular Insights into Carbon Dioxide Sorption in Hydrazone-Based Covalent Organic Frameworks with Tertiary Amine Moieties”, Chemistry of Materials, Feb. 13, 2019, pp. 1946-1955, American Chemi… [cited by applicant]
Hashimoto, Y. et al., “Fabrication of an Anti-Reflective and Super-Hydrophobic Structure by Vacuum Ultraviolet Light-Assisted Bonding and Nanoscale Pattern Transfer”, Micromachines, Apr. 15, 2018, pp. 1-11, www.mdpi.com… [cited by applicant]
Hollis, V. S. et al., “Non-invasive monitoring of brain tissue temperature by near-infrared spectroscopy”, Proceedings of SPIE, Optical Tomography and Spectroscopy of Tissue IV, Jun. 29, 2001, pp. 470-481, vol. 4250, SP… [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, Mailed Mar. 11, 2021, Corresponding to PCT/IB2020/001037, 13 pages. [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Apr. 4, 2023, corresponding to PCT/EP2022/082341, 33 pages. [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Feb. 1, 2022, corresponding to PCT/IB2021/000649, 18 pages. [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Nov. 15, 2021, corresponding to PCT/IB2021/000517, 15 pages. [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Oct. 10, 2022, corresponding to PCT/IB2022/000373, 16 pages. [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Oct. 19, 2022, corresponding to PCT/EP2022/071467, 16 pages. [cited by applicant]
Invitation to Pay Additional Fees and Partial Search Report mailed Feb. 14, 2023 in related International Application No. PCT/EP2022/082341, 18 pages. [cited by applicant]
Izutsu, M. et al., “Integrated Optical SSB Modulator/Frequency Shifter”, IEEE Journal of Quantum Electronics, Nov. 1981, pp. 2225-2227, vol. QE-17, No. 11, IEEE. [cited by applicant]
Kang, J. W. et al., “Direct observation of glucose fingerprint using in vivo Raman spectroscopy,” Science Advances, Jan. 24, 2020, pp. 1-8, American Association for the Advancement of Science. [cited by applicant]
Karlsson, C. J. et al., “All-fiber multifunction continuous-wave coherent laser radar at 1.55 μm for range, speed, vibration, and wind measurements”, Applied Optics, Jul. 20, 2000, pp. 3716-3726, vol. 39, No. 21, Optica… [cited by applicant]
Lai, N. et al., “CO2 Capture With Absorbents of Tertiary Amine Functionalized Nano-SiO2”, Frontiers in Chemistry, Feb. 28, 2020, pp. 1-9, vol. 8, Article 146, www.frontiersin.org. [cited by applicant]
Lapchuk, A. et al., “Investigation of speckle suppression beyond human eye sensitivity by using a passive multimode fiber and a multimode fiber bundle”, Applied Optics, Feb. 21, 2020, pp. 6820-6834, vol. 28, No. 5, Opti… [cited by applicant]
Loi, R. et al., “Transfer Printing of AlGaInAs/InP Etched Facet Lasers to Si Substrates”, IEEE Photonics Journal, Nov. 11, 2016, 11 pages, vol. 8, No. 6, IEEE. [cited by applicant]
Mehta, D. S. et al., “Laser speckle reduction by multimode optical fiber bundle with combined temporal, spatial, and angular diversity”, Applied Optics, Apr. 11, 2012, pp. 1894-1904, vol. 51, No. 12, Optical Society of … [cited by applicant]
Merritt, S. et al., “Monitoring temperature non-invasively using broadband Diffuse Optical Spectroscopy”, OSA/FIO, 2004, 1 page, Optical Society of America, https://opg.optica.org/abstract.cfm?URI=FiO-2004-FTuK4. [cited by applicant]
Noriki, A. et al., “45-degree curved micro-mirror for vertical optical I/O of silicon photonics chip”, Optics Express, Jul. 1, 2019, pp. 19749-19757, vol. 27, No. 14, Optical Society of America, https://doi.org/10.1364/… [cited by applicant]
Poulton, C. V. et al., “Frequency-modulated Continuous-wave LIDAR Module in Silicon Photonics”, OFC, 2015, 4 pages, Optical Society of America. [cited by applicant]
Redding, B. et al., “Compact spectrometer based on a disordered photonic chip”, Nature Photonics, Jul. 28, 2013, pp. 746-751, vol. 7, Macmillan Publishers Limited. [cited by applicant]
Redding, B. et al., “Evanescently coupled multimode spiral spectrometer”, Optica, Aug. 25, 2016, pp. 956-962, vol. 3, No. 9, Optical Society of America. [cited by applicant]
Robinson, M. B., “Interferometric diffuse correlation spectroscopy improves measurements at long source-detector separation and low photon count rate”, Journal of Biomedical Optics, Sep. 30, 2020, pp. 097004-1 through 0… [cited by applicant]
Roelkens, G. et al., “Transfer printing for silicon photonics transceivers and interposers”, 2018 IEEE Optical Interconnects Conference, Jun. 4, 2018, pp. 13-14, IEEE. [cited by applicant]
Ryckeboer, E., “Spectroscopic Detection of Glucose with a Silicon Photonic Integrated Circuit”, Universiteit Gent, Jan. 1, 2014, 263 pages, ISBN 978-90-8578-688-7, http://www.photonics.intec.ugent.be/download/phd_206.pd… [cited by applicant]
Schneider, S. et al., “Optical coherence tomography system mass-producible on a silicon photonic chip”, Optics Express, Jan. 20, 2016, pp. 1573-1586, vol. 24, No. 2, Optical Society of America. [cited by applicant]
Shimotsu, S. et al., “Single Side-Band Modulation Performance of a LiNbO3 Integrated Modulator Consisting of Four-Phase Modulator Waveguides”, IEEE Photonics Technology Letters, Apr. 2001, pp. 364-366, vol. 13, No. 4, I… [cited by applicant]
Subramanian, A. Z. et al., “Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]”, Photon. Res., Aug. 28, 2015, pp. B47-B59, vol. 3, No. 5, Chinese Laser Press. [cited by applicant]
Timm, U. et al., “Non-Invasive Optical Real-time Measurement of Total Hemoglobin Content”, Procedia Engineering, 2010, pp. 488-491, Elsevier Ltd. [cited by applicant]
Tran, T-T-K. et al., “Speckle reduction in laser projection displays through angle and wavelength diversity”, Applied Optics, Feb. 16, 2016, pp. 1267-1274, vol. 55, No. 6, Optical Society of America. [cited by applicant]
Tuchin, V., “Chapter 8: Coherent Effects at the Interaction of Laser Radiation with Tissues and Cell Flows”, Tissue Optics Light Scattering Methods and Instruments for Medical Diagnostics, 3rd Edition, 2015, pp. 359-417… [cited by applicant]
U.S. Appl. No. 18/019,085, filed Jan. 31, 2023. [cited by applicant]
U.S. Appl. No. 18/027,881, filed Mar. 22, 2023. [cited by applicant]
U.S. Appl. No. 18/056,666, filed Nov. 17, 2022. [cited by applicant]
U.S. Notice of Allowance from U.S. Appl. No. 17/757,130, dated Jan. 18, 2023, 10 pages. [cited by applicant]
Valley, G.C. et al., “Multimode waveguide speckle patterns for compressive sensing”, Optics Letters, May 23, 2016, pp. 2529-2532, vol. 41, No. 11, Optical Society of America. [cited by applicant]
Van Gastel, M. et al., “Camera-based pulse-oximetry—validated risks and opportunities from theoretical analysis”, Biomedical Optics Express, Dec. 5, 2017, pp. 102-119, vol. 9, No. 1, Optical Society of America. [cited by applicant]
Website: “Optical Solutions”, Molex, dated 2023, printed May 10, 2023, 13 pages, Molex, LLC, https://www.molex.com/en-us/products/optical-solutions. [cited by applicant]
Website: “Track Your SpO2 to Uncover Changes in Your Wellbeing”, Fitbit News, dated Sep. 7, 2020, printed Apr. 17, 2023, 7 pages, Fitbit, Inc., https://blog.fitbit.com/track-your-spo2/).626. [cited by applicant]
Wenz, J. J., “Examining water in model membranes by near infrared spectroscopy and multivariate analysis”, BBA—Biomembranes, Dec. 9, 2017, pp. 673-682, Elsevier B.V., https://www.sciencedirect.com/science/article/pii/S0… [cited by applicant]
Xu, M. et al., “Laser Speckle Reduction Using a Motionless Despeckle Element Based on Random Mie Scattering”, Journal of Display Technology, Nov. 12, 2013, pp. 151-156, vol. 10, No. 2, IEEE. [cited by applicant]
Yamakoshi, Y. et al., “Side-scattered finger-photoplethysmography: experimental investigations toward practical noninvasive measurement of blood glucose”, Journal of Biomedical Optics, Jun. 2017, pp. 067001-1 through 06… [cited by applicant]
Yao, Z. et al., “Integrated Silicon Photonic Microresonators: Emerging Technologies”, IEEE Journal of Selected Topics in Quantum Electronics, Jun. 11, 2018, 24 pages, vol. 24, No. 6, IEEE. [cited by applicant]
Zhang, J. et al., “III-V-on-Si photonic integrated circuits realized using micro-transfer-printing”, APL Photonics, Nov. 4, 2019, pp. 110803-1 through 110803-10. [cited by applicant]
Zijlstra, W. G. et al., “Absorption Spectra of Human Fetal and Adult Oxyhemoglobin, De-Oxyhemoglobin, Carboxyhemoglobin, and Methemoglobin”, Clinical Chemistry, Sep. 1991, pp. 1633-1638, vol. 37, No. 9, https://academic… [cited by applicant]
Zilkie, A. J. et al., “Multi-Micron Silicon Photonics Platform for Highly Manufacturable and Versitile Photonic Integrated Circuits”, IEEE Journal of Selected Topics in Quantum Electronics, Apr. 15, 2019, 13 pages, vol.… [cited by applicant]
Zilkie, A. J. et al., “Power-efficient III-V/Silicon external cavity DBR lasers”, Optics Express, Sep. 27, 2012, pp. 23456-23462, vol. 20, No. 21, Optical Society of America. [cited by applicant]
U.S. Appl. No. 18/667,608, filed May 17, 2024. [cited by applicant]
U.S. Office Action from U.S. Appl. No. 17/934,502, dated Aug. 31, 2023, 6 pages. [cited by applicant]
U.S. Office Action from U.S. Appl. No. 17/934,502, dated Feb. 1, 2024, 6 pages. [cited by applicant]
Ge, Z. et al., “Dynamic laser speckle analysis using the event sensor”, Applied Optics, Dec. 23, 2020, pp. 172-178, vol. 60, No. 1, Optical Society of America. [cited by applicant]
Ghijsen, M. et al., “Wearable speckle plethysmography (SPG) for characterizing microvascular flow and resistance”, Biomedical Optics Express, Jul. 30, 2018, pp. 3937-3952, vol. 9, No. 8, Optical Society of America under… [cited by applicant]
International Search Report and Written Opinion of the International Searching Authority, mailed Feb. 14, 2023, corresponding to PCT/EP2022/082162, 33 pages. [cited by applicant]
Lai, M. et al., “Perfusion Monitoring by Contactless Photoplethysmography Imaging”, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), Venice, Italy, Apr. 8-11, 2019, pp. 1778-1782, IEEE. [cited by applicant]
Liu, X. et al., “Simultaneous measurements of tissue blood flow and oxygenation using a wearable fiber-free optical sensor”, Journal of Biomedical Optics, Jan. 29, 2021, pp. 012705-1 through 012705-15, vol. 26, No. 1, S… [cited by applicant]
Lu, H. et al., “Single-trial estimation of the cerebral metabolic rate of oxygen with imaging photoplethysmography and laser speckle contrast imaging”, Optics Letters, Mar. 17, 2015, pp. 1193-1196, vol. 40, No. 7, Optic… [cited by applicant]
U.S. Appl. No. 17/934,502, filed Sep. 22, 2022. [cited by applicant]
U.S. Office Action from U.S. Appl. No. 17/934,502, dated Jun. 5, 2024, 7 pages. [cited by applicant]