Granted Patent
B2
US 12,193,742 · App. 17/811,658 · Granted Jan 14, 2025
Optical coherence tomography-based ophthalmic testing methods, devices and systems
Inventors:
Alexander C. Walsh (Los Angeles, CA); Paul G. Updike (Cerritos, CA); Srinivas R. Sadda (Pasadena, CA)
Assignee:
Doheny Eye Institute
A61B3/102A61B3/0025A61B3/0033A61B3/0041A61B3/0091A61B3/028A61B3/085A61B3/113A61B3/117A61B3/18A61B5/0066A61B5/0073
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Abstract
In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data.
Claims (22)
1. An optical coherence tomography system comprising:
an optical coherence tomography instrument comprising:
an eyepiece for receiving at least one eye of a user;
a light source that outputs light that is directed through the eyepiece into the at least one eye of the user;
an interferometer configured to produce optical interference using light reflected from the at least one eye of the user;
an optical detector disposed so as to detect said optical interference;
electronics configured to transmit optical coherence tomography measurements through a network to a remote computing system configured to perform an analysis based on the optical coherence tomography measurements;
wherein said analysis detects at least one of cystoid retinal degeneration, outer retinal edema, subretinal fluid, subretinal tissue, retinal pigment epithelial detachments, or retinal pigment epithelial atrophy, and
wherein the optical coherence tomography instrument is configured to allow the user to self-administer a scan of the at least one eye of the user.
2. The optical coherence tomography system of claim 1 , wherein the eyepiece is a monocular.
3. The optical coherence tomography system of claim 1 , wherein the eyepiece is binocular.
4. The optical coherence tomography system of claim 1 , wherein the light source comprises a superluminescent diode.
5. The optical coherence tomography system of claim 1 , wherein the interferometer comprises a beam combiner or optical grating configured to produce optical interference with said light reflected from the at least one eye of the user.
6. The optical coherence tomography system of claim 1 , wherein the analysis is accessible through a user access device capable of connecting to the network.
7. The optical coherence tomography system of claim 6 , wherein the analysis is accessible through a web-enabled browser module.
8. The optical coherence tomography system of claim 1 , wherein the remote computing system is configured to transmit a report to the user or doctor through the network.
9. The optical coherence tomography system of claim 1 , wherein the remote computing system is configured to determine a risk of maculopathy based on abnormal thickening of a retina or fovea, presence of hyperreflective (bright) or hyporeflective (dark) structures in an outer half of the retina, hyporeflective (dark) structures in an inner half of the retina, irregularities in a contour of a retinal pigment epithelium that depart from a normal curvature of the at least one eye, or hypertransmission of light through the retinal pigment epithelium when compared to a database of normal values.
10. The optical coherence tomography system of claim 1 , wherein the optical coherence tomography instrument comprises an output device electrically coupled to the electronics, the output device configured to provide an output based on the analysis.
11. The optical coherence tomography system of claim 10 , wherein the output device comprises a printer, a display, a server, a laptop computer, a cell phone, a smartphone, a personal digital assistant, a kiosk, or an audio player.
12. The optical coherence tomography instrument of claim 10 , wherein the output is accessible from an Internet site.
13. The optical coherence tomography system of claim 10 , wherein the output comprises at least one of a recommendation to visit a physician, an appointment request, a summary report, a single B-scan image, multiple B-scan, or a recommendation for a referral to a physician.
14. The optical coherence tomography system of claim 10 , wherein the output indicates whether a condition is worsening or whether a condition is improving.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 6, 2024
From: WALSH, ALEXANDER C.; UPDIKE, PAUL G.; SADDA, SRINIVAS R.
To: DOHENY EYE INSTITUTE
Reel/Frame 066671/0647 →
Continuity (18)
Continuation
13054481
Provisional Application
61222080
· Jun 30, 2009
Provisional Application
61221552
· Jun 29, 2009
Provisional Application
61180837
· May 23, 2009
Provisional Application
61168340
· Apr 10, 2009
Provisional Application
61082175
· Jul 18, 2008
Provisional Application
61082171
· Jul 18, 2008
Provisional Application
61040084
· Mar 27, 2008
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