Patient-specific spinal fusion devices and associated systems and methods
The present technology includes patient-specific spinal fusion devices, which may include an interbody implant that is designed to be positioned within a disc space between two vertebral bodies and one or more fixation elements that can anchor the interbody implant to the vertebral bodies. The fusion devices include one or more retention mechanisms for retaining the fixation elements within corresponding lumens or bore holes extending through the interbody implant. Methods for designing and manufacturing patient-specific spinal fusion devices are also described herein.
1 . A patient-specific spinal interbody implant, comprising:
a tapered cage body configured to be delivered anteriorly into spine of a subject, the tapered cage body is asymmetrical with respect to a mid-sagittal plane of the tapered cage body and is asymmetrical with respect to a transverse plane of the tapered cage body, wherein the tapered cage body is configured to receive an anchor configured to anchor the tapered cage body to the spine and includes
a first patient-specific endplate having a patient-contoured region,
a lattice region beneath the patient-contoured region,
a load bearing rim extending at least partially circumferentially about the patient-contoured region, wherein the load bearing rim includes a concave section and a convex section, wherein the patient-contoured region protrudes away from the transverse plane and past the concave section of the load bearing rim such that the patient-contoured region is positioned within a concave region of a first vertebral endplate of the spine and abuts a concave region of a vertebral surface of the spine when the tapered cage body is positioned between the first vertebral endplate and a second vertebral endplate of the spine;
a second patient-specific endplate,
continuous smooth tubular surface defining an anchor-receiving throughhole extending through the tapered cage body, and
one or more struts connected to the continuous smooth tubular surface and extending between the first patient-specific endplate and the second patient-specific endplate.
2 . The patient-specific spinal interbody implant of claim 1 , wherein the second patient-specific endplate with contours different from contours of the first patient-specific endplate.
3 . The patient-specific spinal interbody implant of claim 1 , wherein the tapered cage body includes one or more lattice regions extending along most of a distance between the first patient-specific endplate and a patient-specific second endplate.
4 . The patient-specific spinal interbody implant of claim 1 , wherein the tapered cage body has a graft holding chamber and a sidewall surrounding the graft holding chamber, wherein the sidewall includes a viewing lattice extending through the sidewall and defining a portion of the graft holding chamber.
5 . The patient-specific spinal interbody implant of claim 1 , further comprising:
an anchor configured to be positioned within the anchor-receiving throughhole to extend through an irregular patient-specific contoured surface of the first patient-specific endplate.
6 . The patient-specific spinal interbody implant of claim 1 , wherein the tapered cage body includes a continuous lumen defining the anchor-receiving throughhole that is tubular and arcuate.
7 . A patient-specific spinal interbody implant, comprising:
a cage body configured to be delivered into spine of a subject, the cage body is asymmetrical with respect to a mid-sagittal plane of the cage body and is asymmetrical with respect to a transverse plane of the cage body, wherein the cage body includes
a first patient-specific endplate having a patient-contoured region,
an interior region including a plurality of solid regions and a plurality of lattice regions, wherein each of the solid regions is located between a respective pair of the lattice regions, and
an outer solid rim defining a continuous surface extending along a periphery of the interior region, wherein the outer solid rim includes a concave section and a convex section, wherein the patient-contoured region protrudes outwardly past the concave section, and
an anchor-receiving throughhole extending through the cage body and the patient-contoured region; and
an anchor configured to be positioned within the anchor-receiving throughhole and to extend through the first patient-specific endplate and a first vertebral endplate of the spine of the subject such that the patient-contoured region is positioned along the first vertebral endplate when the cage body is positioned between the first vertebral endplate and a second vertebral endplate of the spine.
8 . The patient-specific spinal interbody implant of claim 7 , further comprising a second patient-specific endplate with contours different from contours of the first patient-specific endplate.
9 . The patient-specific spinal interbody implant of claim 7 , wherein the cage body includes one or more lattice regions extending along most of a distance between the first patient-specific endplate and a patient-specific second endplate.
10 . The patient-specific spinal interbody implant of claim 7 , wherein the cage body has a graft holding chamber and a sidewall surrounding the graft holding chamber, wherein the sidewall includes a viewing lattice extending through the sidewall and defining a portion of the graft holding chamber.
11 . A patient-specific spinal interbody implant comprising:
a cage body configured to be delivered into a spine of a patient, the cage body is asymmetrical with respect to a mid-sagittal plane of the cage body and is asymmetrical with respect to a transverse plane of the cage body, wherein the cage body includes
a first patient-specific endplate having a patient-contoured region,
a lattice region,
an outer solid rim defining a continuous surface extending along a periphery of the first patient-specific endplate, wherein the outer solid rim includes a concave section and a convex section, wherein the patient-contoured region protrudes outwardly past the concave section,
an anchor-receiving throughhole extending through the cage body and the patient-contoured region,
a second patient-specific endplate,
a continuous smooth tubular surface defining the anchor-receiving throughhole extending through the cage body, and
one or more struts connected to the continuous smooth tubular surface and extending between the first patient-specific endplate and the second patient-specific endplate; and
an anchor configured to be positioned within the anchor-receiving throughhole and to extend through the first patient-specific endplate and a first vertebral endplate of the spine of the patient such that the patient-contoured region is positioned along the first vertebral endplate when the cage body is positioned between the first vertebral endplate and a second vertebral endplate of the spine.
12 . The patient-specific spinal interbody implant of claim 7 , wherein the anchor-receiving throughhole has an arcuate lumen extending between the patient-contoured region and a sidewall opening of the cage body.
13 . The patient-specific spinal interbody implant of claim 7 , wherein the cage body includes
a second patient-specific endplate opposite the first patient-specific endplate, and
a solid corner region extending between the first patient-specific endplate and the second patient-specific endplate.
14 . The patient-specific spinal interbody implant of claim 7 , wherein the patient-contoured region extends across most of a side-to-side width of the cage body.
15 . A patient-specific spinal interbody implant comprising:
a cage body including
a first patient-specific endplate having a first patient-contoured region configured to contact a first endplate of a spine of a patient,
a second patient-specific endplate having a second patient-contoured region configured to contact a second endplate of the spine,
a first lattice region positioned between the first patient-specific endplate and the second patient-specific endplate,
a second lattice region positioned between the first patient-specific endplate and the second patient-specific endplate,
a continuous tubular portion defining an anchor-receiving throughhole extending through the cage body, and
a strut extending between the first patient-specific endplate and the second patient-specific endplate, wherein the strut is positioned between the first lattice region and the second lattice region, and wherein the second lattice region is positioned between the strut and an entrance opening of the anchor-receiving throughhole.
16 . The patient-specific spinal interbody implant of claim 15 , further comprising an anchor configured to be positioned in the anchor-receiving throughhole such that the anchor extends into the first endplate of the spine and the continuous tubular portion is located directly between the anchor and the first lattice region.
17 . The patient-specific spinal interbody implant of claim 15 , further comprising:
an anchor, and
a retention mechanism movable relative to the cage body between an unlocked configuration for allowing the anchor to be inserted through the anchor-receiving throughhole and a locked configuration for contacting a head of the anchor when the anchor is positioned in the anchor-receiving throughhole.
18 . The patient-specific spinal interbody implant of claim 15 , wherein the cage body further includes a graft opening extending between the first patient-specific endplate and the second patient-specific endplate, wherein the continuous tubular portion has a convex sidewall that extends toward a longitudinal axis of the graft opening and defines a portion of the graft opening.
19 . The patient-specific spinal interbody implant of claim 18 , wherein the graft opening is configured to be filled with graft material that promotes bone growth between the first endplate and the second endplate of the spine.
20 . The patient-specific spinal interbody implant of claim 18 , wherein a patient-contacting edge of the convex sidewall has a patient-specific topography that matches a topography of the first endplate.
21 . The patient-specific spinal interbody implant of claim 15 , wherein the first patient-specific endplate, the second patient-specific endplate, and the strut are integrally connected together.
22 . The patient-specific spinal interbody implant of claim 21 , wherein the strut extends between the first patient-specific endplate and the second patient-specific endplate.
23 . A patient-specific spinal interbody implant comprising:
a cage configured to be implanted along a spine of a patient, the cage including
a first endplate having a first patient-contoured region,
a second endplate having a second patient-contoured region,
an interior region between the first endplate and the second endplate and including plurality of solid regions and a plurality of lattice regions, wherein each of the plurality of solid regions is located between a respective pair of the plurality of lattice regions, and
an anchor-receiving throughhole extending through the cage and the first patient-contoured region; and
an anchor configured to be positioned within the anchor-receiving throughhole and to extend through the first endplate of the cage and a first anatomical endplate of the spine such that the first patient-contoured region is positioned along the first anatomical endplate.
24 . The patient-specific spinal interbody implant of claim 23 , wherein a tubular portion of one of the plurality of solid regions has a continuous smooth surface that defines the anchor-receiving throughhole.
25 . The patient-specific spinal interbody implant of claim 24 , wherein the cage further includes a graft opening extending between the first endplate and the second endplate, wherein the tubular portion has a convex sidewall that extends toward a central region of the graft opening and defines a portion of the graft opening.
26 . The patient-specific spinal interbody implant of claim 25 , wherein the graft opening is configured to be filled with graft material that promotes bone growth between bony anatomy of the spine.
27 . The patient-specific spinal interbody implant of claim 25 , wherein the convex sidewall has a patient-contacting edge with a patient-specific topography that matches a topography of the first anatomical endplate.
28 . The patient-specific spinal interbody implant of claim 23 , wherein the plurality of lattice regions includes a first lattice region and a second lattice region, and wherein the plurality of solid regions includes a strut positioned between the first lattice region and the second lattice region.
29 . The patient-specific spinal interbody implant of claim 28 , wherein the strut extends between the first endplate and the second endplate.
30 . The patient-specific spinal interbody implant of claim 23 , wherein the first endplate, the second endplate, and the interior region are integrally connected together.
31 . An interbody implant comprising:
a first patient-specific endplate having a first patient-contoured region configured to contact a first endplate of a spine of a patient;
a second patient-specific endplate having a second patient-contoured region configured to contact a second endplate of the spine;
a lattice region positioned between the first patient-specific endplate and the second patient-specific endplate;
a strut positioned between the first patient-specific endplate and the second patient-specific endplate;
a graft opening extending between the first patient-specific endplate and the second patient-specific endplate; and
a tubular portion defining an anchor-receiving throughhole extending through the interbody implant, wherein the tubular portion includes a convex sidewall that extends toward and defines a portion of the graft opening, and wherein the convex sidewall has a patient-contacting edge portion with a patient-specific topography that matches a topography of the first endplate.