Method for preparing nanolipids with encapsulated alcohol
A method for preparing ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages. The method comprises nanolipidic vehicles in which ethanol-containing substances are encapsulated, said ethanol-containing nanolipidic vehicles can be combined with food products, desserts or beverage ingredients including those that are subsequently frozen. The food product, dessert or beverage can remain in a frozen state during consumption by an individual. A composition comprising ethanol-containing nanolipid particles, which can be used in food products, frozen desserts, or beverages.
1. A method for making ethanol-loaded nanolipid particle (NLP) carriers comprising the steps of:
a) providing a monophasic optically clear precursor stock having phospholipids solubilized in ethanol and water;
b) diluting said precursor stock with an ethanol solvent to produce a solvent-diluted precursor stock having substantially unloaded nanolipid particles (NLPs), wherein said diluting of said precursor stock with said ethanol solvent is at a ratio ranging from about 1 part precursor stock to about 20 parts ethanol solvent to a ratio ranging from about 1 part precursor stock to about 0.3 parts ethanol solvent;
c) mixing an ethanol-containing substance suitable for human consumption with an aqueous solvent to produce an aqueous-ethanol monophase; and
d) combining said solvent-diluted precursor stock produced in step (b) with said aqueous-ethanol monophase produced in step (c), wherein the ethanol-containing substance from said aqueous-ethanol monophase in step (c) becomes loaded as a passenger within the nanolipid particles (NLPs) in step (b) forming ethanol-loaded nanolipid particle (NLP) carriers, said ethanol-loaded nanolipid particle (NLP) carriers are sized from 20 nm-300 nm.
2. The method of claim 1 , wherein said ethanol-containing substance suitable for human consumption is an ethanol-containing beverage product.
3. The method of claim 1 , wherein said aqueous-ethanol monophase in step (c) comprises from 12.5% ethanol in water (volume/volume) to 50% ethanol in water (volume/volume).
4. The method of claim 3 , wherein said aqueous-ethanol monophase in step (c) comprises from 15% ethanol in water (volume/volume) to 35% ethanol in water (volume/volume).
5. The method of claim 1 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a food product.
6. The method of claim 5 , wherein said food product is a syrup or topping for a dessert.
7. The method of claim 1 , loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a frozen food product.
8. The method of claim 7 , wherein said frozen food product is a frozen beverage or a frozen dessert.
9. The method of claim 1 , wherein said precursor stock comprises phospholipids selected from the group consisting of phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA), phosphatidylinositol (PI), and mixtures thereof.
10. A method for making ethanol-loaded nanolipid particle (NLP) carriers comprising the steps of:
a) providing a monophasic optically clear precursor stock having phospholipids selected from phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA), phosphatidylinositol (PI), or mixtures thereof, solubilized in ethanol and water;
b) diluting said precursor stock with an ethanol solvent to produce a solvent-diluted precursor stock having substantially unloaded nanolipid particles (NLPs), wherein said diluting of said precursor stock with said ethanol solvent is at a ratio ranging from about 1 part precursor stock to about 20 parts ethanol solvent to a ratio ranging from about 1 part precursor stock to about 0.3 parts ethanol solvent;
c) mixing an ethanol-containing substance suitable for human consumption with an aqueous solvent to produce an aqueous-ethanol monophase; said aqueous-ethanol monophase comprising from 12.5% ethanol in water (volume/volume) to 50% ethanol in water (volume/volume); and
d) combining said solvent-diluted precursor stock produced in step (b) with said aqueous-ethanol monophase produced in step (c), wherein the ethanol-containing substance from said aqueous-ethanol monophase in step (c) becomes loaded as a passenger within the nanolipid particles (NLPs) in step (b) forming ethanol-loaded nanolipid particle (NLP) carriers.
11. The method of claim 10 , wherein said ethanol-loaded nanolipid particle (NLP) carriers are sized from 20 nm-300 nm.
12. The method of claim 10 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a food product.
13. The method of claim 10 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a frozen food product.
14. The method of claim 13 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers combined with one or more ingredient suitable for consumption in a frozen food product are frozen at an appropriate temperature to result in a frozen food product.
15. The method of claim 14 , wherein said frozen food product is a frozen beverage or a frozen dessert.
16. A method for making ethanol-loaded nanolipid particle (NLP) carriers comprising the steps of:
a) providing a monophasic optically clear precursor stock having phospholipids selected from phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA), phosphatidylinositol (PI), or mixtures thereof, solubilized in ethanol and water;
b) diluting said precursor stock with an ethanol solvent to produce a solvent-diluted precursor stock having substantially unloaded nanolipid particles (NLPs), wherein said diluting of said precursor stock with said ethanol solvent is at a ratio ranging from about 1 part precursor stock to about 20 parts ethanol solvent to a ratio ranging from about 1 part precursor stock to about 0.3 parts ethanol solvent;
c) mixing an ethanol-containing substance suitable for human consumption with an aqueous solvent to produce an aqueous-ethanol monophase; said aqueous-ethanol monophase comprising from 15% ethanol in water (volume/volume) to 35% ethanol in water (volume/volume); and
d) combining said solvent-diluted precursor stock produced in step (b) with said aqueous-ethanol monophase produced in step (c), wherein the ethanol-containing substance from said aqueous-ethanol monophase in step (c) becomes loaded as a passenger within the nanolipid particles (NLPs) in step (b) forming ethanol-loaded nanolipid particle (NLP) carriers, wherein said ethanol-loaded nanolipid particle (NLP) carriers are sized from 20 nm-300 nm.
17. The method of claim 16 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a food product.
18. The method of claim 16 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers are combined with one or more ingredient suitable for consumption in a frozen food product.
19. The method of claim 18 , wherein said ethanol-loaded nanolipidic particle (NLP) carriers combined with one or more ingredient suitable for consumption in a frozen food product are frozen at an appropriate temperature to result in a frozen food product.
20. The method of claim 19 , wherein said frozen food product is a frozen beverage or a frozen dessert.