Polymer particles
Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
1. A polymer particle comprising:
poly(ethylene glycol) diacrylamide, glycerol monomethacrylate, and amino ethyl methacrylate;
wherein the polymer particle is spherical and has a diameter less than about 1,200 μm.
2. The polymer particle of claim 1 , wherein the polymer particle has a diameter between about 40 μm and about 1,200 μm.
3. The polymer particle of claim 1 , further comprising N,N-methylenebisacrylamide.
4. The polymer particle of claim 1 , wherein the N,N-methylenebisacrylamide is at a concentration of about 1% w/w.
5. The polymer particle of claim 1 , wherein the poly(ethylene glycol) diacrylamide is at a concentration of about 28% w/w.
6. The polymer particle of claim 1 , wherein the glycerol monomethacrylate is present at a concentration of about 68% w/w.
7. The polymer particle of claim 1 , wherein the amino ethyl methacrylate at a concentration of about 3% w/w.
8. The polymer particle of claim 1 , wherein the poly(ethylene glycol) diacrylamide is poly(ethylene glycol) diacrylamide 10,000.
9. The particle of claim 1 , further comprising a drug.
10. A polymer particle comprising:
poly(ethylene glycol) diacrylamide, 3-sulfopropyl acrylate, and amino propyl methacrylamide,
wherein the polymer particle is spherical and has a diameter less than about 1,200 μm.
11. The polymer particle of claim 10 , wherein the polymer particle has a diameter between about 40 μm and about 1,200 μm.
12. The polymer particle of claim 10 , wherein the poly(ethylene glycol) diacrylamide is at a concentration of about 40% w/w.
13. The polymer particle of claim 10 , wherein the at least one monomer is 3-sulfopropyl acrylate at a concentration of about 59% w/w.
14. The polymer particle of claim 10 , wherein the amino propyl methacrylamide is at a concentration of about 1% w/w.
15. The polymer particle of claim 10 , wherein the poly(ethylene glycol) diacrylamide is poly(ethylene glycol) diacrylamide 10,000.
16. The particle of claim 11 , further comprising a drug.
17. A kit comprising:
a plurality of polymer particles in a container,
wherein the plurality of polymer particles comprise poly(ethylene glycol) diacrylamide, glycerol monomethacrylate, and amino ethyl methacrylate;
wherein the plurality of polymer particles are spherical and have a diameter less than about 1,200 μm.
18. The kit of claim 17 , wherein the container is a vial or a syringe.
19. A kit comprising:
a plurality of polymer particles in a container,
wherein the plurality of polymer particles comprise poly(ethylene glycol) diacrylamide, 3-sulfopropyl acrylate, and amino propyl methacrylamide;
wherein the plurality of polymer particles are spherical and have a diameter less than about 1,200 μm.
20. The kit of claim 19 , wherein the container is a vial or a syringe.