IP Library › Granted Patent US 10,543,299
Granted Patent B2
US 10,543,299 · App. 15/724,135 · Granted Jan 28, 2020

Surface coatings

Inventors: Aaron Baldwin (Orange, CA); John Belletto (Yorba Linda, CA); Wendy Beuthin (San Clemente, CA)
Assignee: MicroVention, Inc.
A61L31/10A61F2/885A61F2/91A61L31/06A61L31/16A61F2210/0076A61F2230/0019A61F2240/001A61F2250/0067A61L2300/42A61L2400/18A61L2420/02
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Quick Facts
Patent No.
US 10,543,299
App. No.
15/724,135
Granted
Jan 28, 2020
Kind
B2
Abstract

Described herein are substrate coatings.

Claims (21)

1. A method of functionalizing a surface of an implantable medical device, the method including:

depositing a dopamine or dopamine-like compound on the surface to form a functionalized surface; and

depositing phosphorylethanolamine on the functionalized surface.

2. The method of claim 1 , further comprising depositing a diamine, multifunctional amine, or multifunctional amine polymer on the functionalized surface.

3. The method of claim 1 , further comprising conjugating a phosphate containing compound onto the functionalized surface.

4. The method of claim 3 , wherein the phosphate containing compound is phosphorylcholine.

5. The method of claim 1 , wherein the dopamine or dopamine-like compound is

6. A method of functionalizing a surface of an implantable medical device, the method including:

depositing a dopamine or dopamine-like compound on the surface to form a functionalized surface; and

depositing taurine on the functionalized surface.

7. The method of claim 6 , further comprising depositing a diamine, multifunctional amine, or multifunctional amine polymer on the functionalized surface.

8. The method of claim 6 , further comprising conjugating a phosphate containing compound onto the functionalized surface.

9. The method of claim 8 , wherein the phosphate containing compound is phosphorylcholine.

10. The method of claim 6 , wherein the dopamine or dopamine-like compound is

11. A method of functionalizing a surface of an implantable medical device, the method including:

depositing a dopamine or dopamine-like compound on the surface to form a functionalized surface; and

depositing a primary amine zwitterion on the functionalized surface.

12. The method of claim 11 , further comprising depositing a diamine, multifunctional amine, or multifunctional amine polymer on the functionalized surface.

13. The method of claim 11 , further comprising conjugating a phosphate containing compound onto the functionalized surface.

14. The method of claim 13 , wherein the phosphate containing compound is phosphorylcholine.

15. The method of claim 11 , wherein the dopamine or dopamine-like compound is

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 3, 2017
From: BALDWIN, AARON; BELLETTO, JOHN; BEUTHIN, WENDY
To: MICROVENTION, INC.
Reel/Frame 043771/0786 →
Continuity (2)
Provisional Application 62403562 · Oct 3, 2016
Related Publication 20180093019A1 · Apr 5, 2018
Cited By (4)
US 12,252,658 US 12,257,370 US 12,514,960 US 12,558,462