Methods of improving athletic performance with inorganic nitrate compositions
A method for improving athletic or physical performance in a human includes administering to the human a composition or supplement formulation including a single administration of inorganic nitrate (NO 3 − ), a single administration of inorganic nitrite (NO 2 − ), or a combination thereof; and an additive. A method for increasing endurance in a human includes administering to the human a composition or supplement formulation including a single administration of inorganic nitrate (NO 3 − ), a single administration of inorganic nitrite (NO 2 − ), or a combination thereof; and an additive.
1. A method for improving athletic performance in a human, the method comprising orally administering to the human a composition or supplement formulation comprising:
i) a salt of nitric acid selected from the group consisting of: barium nitrate and amino acid nitrate, wherein the amino acid nitrate is salt of an amino acid selected from the group consisting of: agmatine, beta alanine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, leucine, isoleucine, lysine, methionine, proline, serine, threonine, tryptophan, tyrosine, valine, citrulline, creatine, glutamine, norvaline, ornithine, and phenylalanine; and
ii) an additive selected from the group consisting of a carrier, an excipient, a binder, a colorant, a flavoring agent, a preservative, a buffer, a dilutant, an antioxidant, and a combination thereof.
2. The method of claim 1 , wherein the additive comprises an antioxidant.
3. The method of claim 1 , wherein the composition or supplement formulation consists essentially of:
i) the salt of nitric acid; and
ii) the additive.
4. The method of claim 3 , wherein the composition or supplement formulation consists essentially of the salt of nitric acid and an antioxidant.
5. The method of claim 1 , wherein the composition or supplement formulation is in the form of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, or a syrup.
6. A method for improving physical performance in a human, the method comprising orally administering to the human a composition or supplement formulation comprising:
i) a salt of nitric acid selected from the group consisting of: barium nitrate and amino acid nitrate, wherein the amino acid nitrate is salt of an amino acid selected from the group consisting of: agmatine, beta alanine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, leucine, isoleucine, lysine, methionine, proline, serine, threonine, tryptophan, tyrosine, valine, citrulline, creatine, glutamine, norvaline, ornithine, and phenylalanine; and
ii) an additive selected from the group consisting of a carrier, an excipient, a binder, a colorant, a flavoring agent, a preservative, a buffer, a dilutant, an antioxidant, and a combination thereof.
7. The method of claim 6 , wherein the additive comprises an antioxidant.
8. The method of claim 6 , wherein the composition or supplement formulation consists essentially of:
i) the salt of nitric acid selected from the group consisting of: barium nitrate and amino acid nitrate, wherein the amino acid nitrate is salt of an amino acid selected from the group consisting of: agmatine, beta alanine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, leucine, isoleucine, lysine, methionine, proline, serine, threonine, tryptophan, tyrosine, valine, citrulline, creatine, glutamine, norvaline, ornithine, and phenylalanine; and
ii) the additive.
9. The method of claim 7 , wherein the composition or supplement formulation consists essentially of the salt of nitric acid and the antioxidant.
10. The method of claim 6 , wherein the composition or supplement formulation is in the form of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, or a syrup.
11. The method of claim 1 , wherein the additive is the carrier.
12. The method of claim 1 , wherein the additive is the excipient.
13. The method of claim 1 , wherein the additive is the binder.
14. The method of claim 1 , wherein the additive is the colorant.
15. The method of claim 1 , wherein the additive is the flavoring agent.
16. The method of claim 6 , wherein the additive is the carrier.
17. The method of claim 6 , wherein the additive is the excipient.
18. The method of claim 6 , wherein the additive is the binder.
19. The method of claim 6 , wherein the additive is the colorant.
20. The method of claim 6 , wherein the additive is the flavoring agent.
21. The method of claim 5 , wherein the composition or supplement formulation is a pill.
22. The method of claim 5 , wherein the composition or supplement formulation is a tablet.
23. The method of claim 5 , wherein the composition or supplement formulation is a capsule.
24. The method of claim 5 , wherein the composition or supplement formulation is a powder.
25. The method of claim 5 , wherein the composition or supplement formulation is a liquid.
26. The method of claim 10 , wherein the composition or supplement formulation is a pill.
27. The method of claim 10 , wherein the composition or supplement formulation is a tablet.
28. The method of claim 10 , wherein the composition or supplement formulation is a capsule.
29. The method of claim 10 , wherein the composition or supplement formulation is a powder.
30. The method of claim 1 , wherein the composition or supplement formulation comprises an effective amount of the salt of nitric acid sufficient to improve athletic performance in a human.
31. The method of claim 6 , wherein the composition or supplement formulation comprises an effective amount of the salt of nitric acid sufficient to improve physical performance in a human.
32. The method of claim 3 , wherein the salt of nitric acid is in an effective amount sufficient to improve athletic performance in a human.
33. The method of claim 8 , wherein the salt of nitric acid is in an effective amount sufficient to improve physical performance in a human.
34. The method of claim 1 , wherein the salt of nitric acid is an amino acid nitrate.
35. The method of claim 6 , wherein the salt of nitric acid is an amino acid nitrate.
36. The method of claim 3 , wherein the salt of nitric acid is barium nitrate.
37. The method of claim 3 , wherein the salt of nitric acid is an amino acid nitrate.
38. The method of claim 8 , wherein the salt of nitric acid is barium nitrate.
39. The method of claim 8 , wherein the salt of nitric acid is an amino acid nitrate.
40. The method of claim 32 , wherein the salt of nitric acid is an amino acid nitrate.
41. The method of claim 33 , wherein the salt of nitric acid is barium nitrate.
42. The method of claim 33 , wherein the salt of nitric acid is an amino acid nitrate.
43. The method of claim 1 , wherein the amino acid nitrate is the salt of L-histidine.
44. The method of claim 1 , wherein the amino acid nitrate is the salt of phenylbeta-alanine.
45. The method of claim 6 , wherein the amino acid nitrate is the salt of L-histidine.
46. The method of claim 6 , wherein the amino acid nitrate is the salt of phenylbeta-alanine.