Granted Patent
B2
US 12,540,119 · App. 19/030,637 · Granted Feb 3, 2026
Amino acid compositions
Assignee:
ThermoLife International, LLC
C07D233/64A61K31/185A61K31/197A61K31/198A61K31/205A61K31/221A61K31/401A61K31/4172A61K33/00C07C229/08C07C229/24C07C229/26C07C237/06C07C275/16C07C279/02C07C323/58C07D207/16
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Abstract
Semisolid supplement compositions are disclosed comprising at least one non-ester nitrate compound and at least one isolated amino acid compound. The at least one isolated amino acid compound is a separate compound than the at least one non-ester nitrate compound. The composition contains at least about 0.05625 mg nitrate ion (NO 3 − ).
Claims (34)
1 . A semisolid supplement composition comprising:
at least one non-ester nitrate compound; and
at least one isolated amino acid compound selected from Tyrosine and Trimethylglycine;
wherein the at least one isolated amino acid compound is a separate compound than the at least one non-ester nitrate compound; and
wherein the semisolid supplement composition comprises an amount of nitrate ion (NO 3 − ) that is at least about 0.05625 mg.
2 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is least about 0.33125 mg.
3 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is least about 0.33125 mg.
4 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is least about 1 mg.
5 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is least about 1 mg.
6 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is least about 5 mg.
7 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is least about 5 mg.
8 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is least about 10 mg.
9 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is least about 10 mg.
10 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is least about 20 mg.
11 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 ) is least about 20 mg.
12 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is about 0.33125 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
13 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is about 0.33125 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
14 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is about 1 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
15 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is about 1 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
16 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
17 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 31.6 mg of nitrate ion (NO 3 − ).
18 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the semisolid supplement composition comprises one or more of the following: beetroot, spinach, and rocket.
19 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the semisolid supplement composition comprises one or more of the following: beetroot, spinach, and rocket.
20 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the semisolid supplement composition comprises at least one isolated non-ester nitrate compound.
21 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the semisolid supplement composition comprises at least one isolated non-ester nitrate compound.
22 . The composition of claim 1 , wherein the semisolid supplement composition contains a pharmaceutically effective amount of Tyrosine.
23 . The composition of claim 1 , wherein the semisolid supplement composition contains a pharmaceutically effective amount of Trimethylglycine.
24 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the semisolid supplement composition is ready for distribution to a consumer.
25 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the semisolid supplement composition is ready for distribution to a consumer.
26 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and is isolated from a botanical source.
27 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and is isolated from a botanical source.
28 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Tyrosine and the at least one non-ester nitrate compound is from a vegetable nitrate source.
29 . The composition of claim 1 , wherein the at least one isolated amino acid compound is Trimethylglycine and the at least one non-ester nitrate compound is from a vegetable nitrate source.
30 . The composition of claim 1 , wherein the amount of nitrate ion (NO 3 − ) is about 5 mg to no more than about 10 mg of nitrate ion (NO 3 − ).
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 19, 2025
From: KRAMER, RONALD; NIKOLAIDIS, ALEXANDROS
To: THERMOLIFE INTERNATIONAL, LLC
Reel/Frame 070265/0471 →
Continuity (8)
Continuation
17522680
· Nov 9, 2021
Division
14621738
· Feb 13, 2015
Continuation
13920066
· Jun 17, 2013
Provisional Application
60973229
· Sep 18, 2007
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