Heart failure management
Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein.
1. A method, comprising:
delivering a therapy using an implantable device to electrically stimulate a heart muscle or an autonomic neural target using stimulation parameters;
receiving parameter values, wherein the received parameter values include parameter values for at least a respiration parameter and a heart sound parameter;
using an algorithm to process the received parameter values; and
changing the stimulation parameters based on the processed received parameter values.
2. The method of claim 1 , wherein the received parameter values further include parameter values for a patient activity parameter.
3. The method of claim 1 , wherein the therapy includes electrical stimulation of the heart muscle.
4. The method of claim 1 , wherein the therapy includes electrical stimulation of the autonomic neural target.
5. The method of claim 1 , wherein the received parameter values, processed using the algorithm, further include a heart rate variability (HRV) measurement.
6. The method of claim 1 , wherein the received parameter values, processed using the algorithm, further include a heart rate turbulence (HRT) measurement.
7. The method of claim 1 , wherein the received parameter values, processed using the algorithm, further include a blood pressure measurement.
8. The method of claim 1 , wherein at least some of the parameter values are received from at least one of: a sensor, a physician input, a patient input, a patient history data source, a pharmaceutical data source, and a population/clinical study data source.
9. The method of claim 1 , wherein the parameter values for the respiration parameter include a transthoracic impedance.
10. The method of claim 1 , wherein the parameter values for the respiration parameter include a minute ventilation.
11. The method of claim 1 , wherein the parameter values for the respiration parameter include a tidal volume.
12. The method of claim 1 , wherein the received parameter values further include an exercise activity.
13. The method of claim 1 , wherein the received parameter values further include a heart rate or a respiration rate.
14. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to:
deliver a therapy using an implantable device to electrically stimulate a heart muscle or an autonomic neural target using stimulation parameters;
receive parameter values, wherein the received parameter values include parameter values for at least a respiration parameter and a heart sound parameter;
use an algorithm to process the received parameter values;
and
change the stimulation parameters based on the processed received parameter values.
15. The non-transitory machine-readable medium of claim 14 , wherein at least some of the parameter values are received from at least one of: a sensor, a physician input, a patient input data source, a patient history data source, a pharmaceutical data source, and a population/clinical study data source.
16. The non-transitory machine-readable medium of claim 14 , wherein the received parameter values further include parameter values for a patient activity parameter.
17. A system, comprising:
an implantable heart failure therapy delivery system configured to deliver a heart failure (HF) therapy to electrically stimulate a heart muscle or an autonomic neural target; and
control circuitry operably connected to the therapy delivery system and configured to:
receive parameter values, wherein the received parameter values include parameter values for at least a respiration parameter and a heart sound parameter;
generate at least a first HF status index and a second HF status index from the received parameter values; and
change the electrical stimulation based on the received parameter values.
18. The system of claim 17 , wherein the control circuitry is configured to receive parameter values from one or more data source types selected from a group of data source types consisting of: a sensor data source type, a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
19. The system of claim 17 , wherein the implantable heart failure therapy delivery system is configured to electrically stimulate the heart muscle to deliver the HF therapy.
20. The system of claim 17 , wherein the implantable heart failure therapy delivery system is configured to electrically stimulate the autonomic neural target to deliver the HF therapy.