Peptide compositions and methods for ameliorating skin laxity and body contour
Compositions and methods for amelioration of skin laxity and body contour are provided. Provided herein are compositions comprising a combination of peptides.
1. A method for improving skin laxity, texture, or crepiness, or for improving body contouring, comprising:
administering a topical composition comprising:
a tripeptide-1,
a hexapeptide-11,
a hexapeptide-12, wherein the topical composition improves skin laxity, texture, or crepiness or body contouring.
2. The method of claim 1 , wherein the topical composition is administered in conjunction with a body-shaping procedure or following a body-shaping procedure.
3. The method of claim 1 , wherein the topical composition is administered up to one day following a body-shaping procedure.
4. The method of claim 2 , wherein the body-shaping procedure comprises high frequency focused ultrasound, pulsed focus ultrasound, cryolipolysis, radiofrequency induced electroporation, injectable lipolytic agents, liposuction, a surgical body contouring procedure, or combinations thereof.
5. The method of claim 1 , wherein the topical composition is administered one, two, three, four, five, or six times a day.
6. The method of claim 1 , wherein the topical composition is administered for at least one week, 2 weeks, 4 weeks, 8 weeks, or 12 weeks.
7. The method of claim 1 , wherein the tripeptide 1 is present at 1-10 ppm.
8. The method of claim 1 , wherein further comprising a tetrapeptide.
9. The method of claim 1 , wherein the hexapeptide-11 is present at about 0.001% to about 6% by weight.
10. The method of claim 1 , wherein the hexapeptide-12 is present at about 0.5-10 ppm.
11. The method of claim 1 , wherein the topical composition further comprises one or more additional ingredients selected from the group consisting of ceramide NP, Tremella fuciformis extract, niacinamide, hydrogenated lecithin, C12-16 alcohols, palmitic acid, avocado extract, shea butter, bentonite, phytoene/phytofluene, hydroxymethoxyphenyl decanone, polyholosides, Plantago lanceolata , dill extract, phosphatidylserine, oleuropein, hydrolyzed Candida saitoana extract, Centella asiatica , propanediol, lecithin, Euglena gracilis extract, aqua, caffeine, Glaucium flavum leaf extract, or combinations thereof.
12. The method of claim 1 , wherein the hexapeptide-11 is present at about 0.002% to about 4% by weight.
13. The method of claim 1 , wherein the hexapeptide-11 is present at about 0.005% to about 0.02% by weight.
14. The method of claim 1 , wherein the topical composition is administered in conjunction with a non-invasive body-shaping procedure or following a non-invasive body-shaping procedure.
15. The method of claim 1 , wherein the topical composition is administered up to 2 days, 3 days, 4 days, 5 days, 6 days, 1 week, 2 weeks, 3 weeks, 1 month, 2 months, 3 months, 4 months, 5 months, or 6 months following a body-shaping procedure.
16. The method of claim 8 , wherein the tetrapeptide is tetrapeptide-2.
17. The method of claim 8 , wherein the tetrapeptide is present at 1-10 ppm.