IP Library › Granted Patent US 11,278,649
Granted Patent B2
US 11,278,649 · App. 16/712,582 · Granted Mar 22, 2022

Surface coatings

Inventors: Aaron Baldwin (Orange, CA); John Belletto (Yorba Linda, CA); Wendy Beuthin (San Clemente, CA)
Assignee: MicroVention, Inc.
A61L31/10A61F2/885A61F2/91A61L31/06A61L31/16A61F2/82A61F2210/0076A61F2230/0019A61F2240/001A61F2250/0067A61L2300/42A61L2400/18A61L2420/02
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Quick Facts
Patent No.
US 11,278,649
App. No.
16/712,582
Granted
Mar 22, 2022
Kind
B2
Abstract

Described herein are substrate coatings.

Claims (23)

1. An implantable device, including a surface having a coating, wherein the coating includes:

a polydopamine coating deposited on the surface, wherein the polydopamine coating is formed from at least one dopamine or dopamine-like compound; and

a coating deposited on the polydopamine coating, wherein the coating deposited on the polydopamine coating is formed from at least one primary amine zwitterion.

2. The implantable device of claim 1 , wherein the dopamine or dopamine-like compound increases positive charge on the implantable device.

3. The implantable device of claim 1 , wherein the dopamine or dopamine-like compound increases negative charge on the implantable device.

4. The implantable device of claim 1 , wherein the coating induces a faster occlusion time when compared to a non-coated device.

5. The implantable device of claim 1 , wherein the implantable device is a flat coupon, a hypo tube, a wire, a woven wire, a stent, or a laser cut object.

6. The implantable device of claim 1 , wherein the implantable device is a stent.

7. The implantable device of claim 1 , wherein the coating further includes a diamine, multifunctional amine, or multifunctional amine polymer.

8. The implantable device of claim 1 , wherein the at least one primary amine zwitterion includes a phosphate-containing primary amine zwitterion.

9. The implantable device of claim 1 , wherein the at least one dopamine or dopamine-like compound includes

or a combination thereof.

10. The implantable device of claim 1 , wherein the at least one primary amine zwitterion includes phosphorylethanolamine.

11. The implantable device of claim 1 , wherein the at least one primary amine zwitterion includes taurine.

12. The implantable device of claim 1 , wherein the coating deposited on the polydopamine coating includes

13. The implantable device of claim 1 , wherein the coating deposited on the polydopamine coating includes

14. The implantable device of claim 1 , wherein the coating deposited on the polydopamine coating includes

15. The implantable device of claim 1 , wherein the coating includes

or a combination thereof.

16. The implantable device of claim 1 , wherein the coating includes a phosphoramidate.

17. The implantable device of claim 1 , wherein the coating deposited on the polydopamine coating includes a phosphorylcholine polymer.

18. The implantable device of claim 1 , wherein the polydopamine coating is covalently deposited on the surface.

19. The implantable device of claim 1 , wherein the coating deposited on the polydopamine coating is covalently deposited on the polydopamine coating.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2019
From: BALDWIN, AARON; BELLETTO, JOHN; BEUTHIN, WENDY
To: MICROVENTION, INC.
Reel/Frame 051269/0152 →
Continuity (3)
Division 15724135 · Oct 3, 2017
Provisional Application 62403562 · Oct 3, 2016
Related Publication 20200222594A1 · Jul 16, 2020
Cited By (4)
US 12,252,658 US 12,257,370 US 12,514,960 US 12,558,462