IP Library › Granted Patent US 11,312,714
Granted Patent B2
US 11,312,714 · App. 16/627,630 · Granted Apr 26, 2022

Compositions and methods for modulating hair growth

Inventors: William E. Lowry (Los Angeles, CA); Michael E. Jung (Los Angeles, CA); Heather R. Christofk (Los Angeles, CA); Xiaoguang Liu (Santa Monica, CA); Aimee Flores (Los Angeles, CA)
Assignee: The Regents of the University of California
C07D471/04A61K9/0014A61P17/14C07D209/22C07D413/06C07D417/06C07F9/535
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Quick Facts
Patent No.
US 11,312,714
App. No.
16/627,630
Granted
Apr 26, 2022
Kind
B2
Abstract

The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.

Claims (3)

1. A method of promoting hair growth or treating a condition or disorder affecting hair growth, comprising administering to a patient an MPC inhibitor or an MPO inhibitor.

2. The method of claim 1 , wherein the condition or disorder is baldness.

3. The method of claim 1 , wherein the condition or disorder is alopecia.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2021
From: FLORES, AIMEE
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 057043/0699 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2021
From: LOWRY, WILLIAM E.; JUNG, MICHAEL E.; CHRISTOFK, HEATHER R.; LIU, XIAOGUANG
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 057262/0293 →
Continuity (3)
Provisional Application 62527775 · Jun 30, 2017
Provisional Application 62654095 · Apr 6, 2018
Related Publication 20200157093A1 · May 21, 2020
Cited By (3)
US 12,227,503 US 12,559,490 US 12,649,736