IP Library Granted Patent US 11,324,973
Granted Patent B2
US 11,324,973 · App. 17/016,372 · Granted May 10, 2022

Multi-color charged particle detector apparatus and method of use thereof

Inventors: Maureen Petterson (Somerville, MA); W. Davis Lee (Rockport, ME)
A61N5/1077A61B6/03A61N5/1044A61N5/1067A61N5/1082G21K1/087G21K1/093G21K5/04A61N5/107A61N2005/1074A61N2005/1087A61N2005/1097H01J35/14
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Quick Facts
Patent No.
US 11,324,973
App. No.
17/016,372
Filed
Sep 10, 2020
Granted
May 10, 2022
Kind
B2
Art Unit
2881
USPC
600/1
Abstract

The invention comprises a method and apparatus for using a multi-layer multi-color scintillation based detector element to image a tumor of a patient using a process of determining residual energies of positively charged particles after passing through the patient, the process comprising the steps of: (1) transmitting the positively charged particles at known energies through the patient and into a multi-layer detector element; (2) detecting first and second secondary photons, resultant from passage of the positively charged particles, respectively from a first layer of a first scintillation material and a second layer of a second scintillation material at two respective layer depths, where the first wavelength range differs from the second wavelength range; (4) determining residual energies of the positively charged particles, using output from the step of detecting; and (5) relating the residual energies to body densities to generate an image.

Claims (24)

1. An apparatus for determining residual energy of positively charged particles after passing through a patient, comprising:

a multi-layer detector, comprising;

a first layer comprising a first scintillation material, said first scintillation material, responsive to passage of the positively charged particles, emitting first secondary photons over a first wavelength range; and

a second layer comprising a second scintillation material, said second scintillation material, responsive to passage of the positively charged particles, emitting second secondary photons over a second wavelength range, the first scintillation material differing from the second scintillation material.

2. The apparatus of claim 1 , said multi-layer detector further comprising:

a third layer comprising a third scintillation material, said third scintillation material, responsive to passage of the positively charged particles, emitting third secondary photons over a third wavelength range, said third scintillation material differing from both said first scintillation material and said second scintillation material.

3. The apparatus of claim 2 , said multi-layer detector further comprising:

a first sub-stack of scintillation materials comprising said first layer, said second layer, and said third layer; and

a second sub-stack comprising a manufactured copy of said first sub-stack.

4. The apparatus of claim 3 , said multi-layer detector further comprising:

at least ten layers of scintillation materials, said at least ten layers of scintillation materials comprising:

said first sub-stack; and

said second sub-stack.

5. The apparatus of claim 1 , further comprising:

an imaging system configured to use output from said multi-layer detector to generate an image of a tumor of the patient.

6. A method for determining residual energy of positively charged particles after passing through a patient, comprising the steps of:

passing the positively charged particles into a multi-layer detector element;

detecting first secondary photons, resultant from passage of the positively charged particles, over a first wavelength range from a first layer of said multi-layer detector, said first layer comprising a first scintillation material; and

detecting second secondary photons, resultant from passage of the positively charged particles, over a second wavelength range from a second layer of said multi-layer detector element, the first wavelength range differing from the second wavelength range;

accelerating the positively charged particles using an accelerator;

transporting the positively charged particles from said accelerator, through the patient, and into said multi-layer detector element of a detection system; and

generating an image of a tumor of the patient from output from said multi-layer detector element.

7. The method of claim 6 , further comprising the step of:

detecting third secondary photons, resultant from passage of the positively charged particles, over a third wavelength range from a third layer of said multi-layer detector element, a third mean wavelength of the third wavelength range differing from both a first mean wavelength of the first wavelength range and a second mean wavelength of the second wavelength range by at least ten nanometers.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2023
From: PETTERSON, MAUREEN; LEE, W DAVIS
To: PROTOM INTERNATIONAL HOLDING CORPORATION
Reel/Frame 062383/0646 →
Continuity (15)
Continuation In Part 16538648 · Aug 12, 2019
Continuation In Part 15901770 · Feb 21, 2018
Continuation In Part 15892240 · Feb 8, 2018
Continuation In Part 15868897 · Jan 11, 2018
Continuation In Part 15838072 · Dec 11, 2017
Continuation In Part 15823148 · Nov 27, 2017
Continuation In Part 15467840 · Mar 23, 2017
Continuation In Part 15402739 · Jan 10, 2017
Continuation In Part 15348625 · Nov 10, 2016
Continuation In Part 15167617 · May 27, 2016
Continuation 15152479 · May 11, 2016
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13087096 · Apr 14, 2011
Provisional Application 61324776 · Apr 16, 2010
Related Publication 20200406063A1 · Dec 31, 2020
Cited By (1)
US 12,474,163