IP Library › Granted Patent US 11,612,741
Granted Patent B2
US 11,612,741 · App. 17/005,461 · Granted Mar 28, 2023

Patterned stimulation intensity for neural stimulation

Inventors: Dustin Tyler (Highland Heights, OH); Daniel Tan (Cleveland, OH); Matthew Schiefer (Shaker Heights, OH); Ronald J. Triolo (Cleveland Heights, OH)
Assignee: CASE WESTERN RESERVE UNIVERSITY
A61N1/0551A61N1/361A61N1/36003A61N1/36014A61N1/3615A61N1/36031A61N1/36034A61N1/36067A61N1/36103A61N1/36139A61N1/36146A61N1/36178A61N1/36189
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Quick Facts
Patent No.
US 11,612,741
App. No.
17/005,461
Granted
Mar 28, 2023
Kind
B2
Abstract

One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.

Claims (33)

1. A method comprising:

receiving a sensor signal in response to an action

configuring a stimulation signal with a pattern of stimulation intensities based on the sensor signal;

delivering the stimulation signal to one or more nerves of the individual,

wherein the individual experiences a virtual sensation based on the stimulation signal being delivered to the one or more nerves of the individual.

2. The method of claim 1 , wherein the individual is an amputee and the virtual sensation is related to an amputated body part.

3. The method of claim 1 , wherein the individual is a diseased individual and the virtual sensation is related to a diseased body part.

4. The method of claim 1 , wherein the individual is an able bodied individual and the virtual sensation is related to an intact body part.

5. The method of claim 1 , further comprising:

receiving another sensor signal in response to another action; and

reconfiguring the stimulation signal with a different pattern of stimulation intensities based on a different virtual sensation to be felt by the individual.

6. The method of claim 1 , wherein the one or more nerves of the individual comprise a plurality of sensory fibers, and

wherein the stimulation signal is configured to activate at least a portion of the sensory fibers.

7. The method of claim 1 , wherein the virtual sensation is related to pain relief.

8. The method of claim 1 , wherein the action is performed by or on a device external to the individual.

9. The method of claim 1 , wherein the action is performed at a location of the individual and/or at a location remote from the individual.

10. A system comprising:

a pulse generator configured to:

configure a stimulation signal with a pattern of stimulation intensities based on a sensor signal received in response to an action; and

generate the stimulation signal;

at least one electrode configured to deliver the stimulation signal to one or more nerves of an individual to cause the individual to experience a virtual sensation.

11. The system of claim 10 , wherein the one or more electrodes are configured to at least partially surround the one or more nerves.

12. The system of claim 10 , wherein the individual is an amputee and the virtual sensation is related to an amputated body part.

13. The system of claim 10 , wherein the individual is a diseased individual and the virtual sensation is related to a diseased body part.

14. The system of claim 10 , wherein the individual is an able bodied individual and the virtual sensation is related to an intact body part.

15. The system of claim 10 , wherein the one or more nerves of the individual comprise sensory fibers,

wherein the stimulation signal is configured to deliver a sensation to the sensory fibers so that the individual experiences the virtual sensation.

16. The system of claim 10 , wherein the action is performed by the individual.

17. The system of claim 10 , wherein the action is performed by or on a device external to the individual.

18. The system of claim 10 , wherein the action is performed at a location of the individual and/or at a location remote from the individual.

19. The system of claim 10 , wherein the virtual sensation allows the individual to experience a sensation when the individual otherwise would not be able to experience the sensation,

wherein the pattern of stimulation intensities mimic actual biological signals.

20. The system of claim 10 , wherein the virtual sensation is related to pain relief.

Continuity (5)
Continuation 16918134 · Jul 1, 2020
Continuation 16175967 · Oct 31, 2018
Continuation 15104589
Continuation PCTUS2013075329 · Dec 16, 2013
Related Publication 20200391025A1 · Dec 17, 2020