IP Library Granted Patent US 11,622,812
Granted Patent B2
US 11,622,812 · App. 17/534,981 · Granted Apr 11, 2023

Systems and methods for correction of artificial deformation in anatomic modeling

Inventors: Leo Grady (Darien, CT); Michiel Schaap (Leiden, NL); Sophie Khem (San Francisco, CA); Sarah Wilkes (San Mateo, CA); Ying Bai (Belmont, CA)
Assignee: HeartFlow, Inc.
A61B34/10G06F30/20G06K9/6215G06K9/6267G06T7/0012G06T7/60G06T7/70G09B9/00G09B23/303G16B5/00G16H50/50A61B6/5258A61B2034/105G06T13/20G06T2207/10004G06T2207/30101G06T2207/30104
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Quick Facts
Patent No.
US 11,622,812
App. No.
17/534,981
Filed
Nov 24, 2021
Granted
Apr 11, 2023
Kind
B2
Art Unit
2669
USPC
382/128
Abstract

Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.

Claims (48)

1. A computer-implemented method of correcting anatomical modeling, the method comprising:

obtaining a plurality of patient-specific images including a vessel and a portion of myocardial tissue;

obtaining a vessel model including the vessel and the portion of myocardial tissue;

determining a bridged portion within the portion of myocardial tissue based on the plurality of patient-specific images;

comparing a local radiodensity within the plurality of patient-specific images of the vessel;

computing a radius or local area for a non-bridged portion of the vessel; and

modifying the vessel model within the bridged portion of myocardial tissue based on the computed radius or local area.

2. The method of claim 1 , further including:

performing one or more simulations using the modified vessel model.

3. The method of claim 2 , further including

providing a medical assessment based on the one or more simulations.

4. The method of claim 1 , wherein the vessel model includes implicit or explicit local area information.

5. The method of claim 1 , wherein modifying the vessel model includes creating an updated vessel model with the computed radius centered on a centerline.

6. The method of claim 1 , further including:

outputting the modified vessel model to an electronic storage device.

7. The method of claim 1 , wherein comparing the local radiodensity determines whether the portion of the myocardial tissue is in contact with the vessel.

8. The method of claim 1 , wherein determining the bridged portion includes determining the bridged portion via tunneling.

9. A system for correcting anatomical modeling, the system comprising:

a data storage device storing instructions for correcting anatomical modeling; and

a processor configured to execute the instructions to perform operations comprising:

obtaining a plurality of patient-specific images including a vessel and a portion of myocardial tissue;

obtaining a vessel model including the vessel and the portion of myocardial tissue;

determining a bridged portion within the portion of myocardial tissue based on the plurality of patient-specific images;

comparing a local radiodensity within the plurality of patient-specific images of the vessel;

computing a radius or local area for a non-bridged portion of the vessel; and

modifying the vessel model within the bridged portion of myocardial tissue based on the computed radius or local area.

10. The system of claim 9 , the operations further comprising:

performing one or more simulations using the modified vessel model.

11. The system of claim 10 , the operations further comprising:

providing a medical assessment based on the one or more simulations.

12. The system of claim 9 , wherein the vessel model includes implicit or explicit local area information.

13. The system of claim 9 , wherein modifying the vessel model includes creating an updated vessel model with the computed radius centered on a centerline.

14. The system of claim 9 , the operations further comprising:

outputting the modified vessel model to an electronic storage device.

15. The system of claim 9 , wherein comparing the local radiodensity determines whether the portion of the myocardial tissue is in contact with the vessel.

16. The system of claim 9 , wherein determining the bridged portion includes determining the bridged portion via tunneling.

17. A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for performing operations correcting anatomical modeling, the operations comprising:

obtaining a plurality of patient-specific images including a vessel and a portion of myocardial tissue;

obtaining a vessel model including the vessel and the portion of myocardial tissue;

determining a bridged portion within the portion of myocardial tissue based on the plurality of patient-specific images;

comparing a local radio density within the plurality of patient-specific images of the vessel;

computing a radius or local area for a non-bridged portion of the vessel; and

modifying the vessel model within the bridged portion of myocardial tissue based on the computed radius or local area.

18. The non-transitory computer readable medium of claim 17 , wherein the operations further comprise:

performing one or more simulations using the modified vessel model.

19. The non-transitory computer readable medium of claim 18 , wherein the operations further comprise:

providing a medical assessment based on the one or more simulations.

20. The non-transitory computer readable medium of claim 17 , wherein the vessel model includes implicit or explicit local area information.

Assignments (2)
SECURITY INTEREST Recorded Jun 18, 2024
From: HEARTFLOW, INC.
To: HAYFIN SERVICES LLP
Reel/Frame 067775/0966 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2021
From: GRADY, LEO; SCHAAP, MICHIEL; KHEM, SOPHIE; WILKES, SARAH; BAI, YING
To: HEARTFLOW, INC.
Reel/Frame 058330/0523 →
Continuity (8)
Continuation 16871216 · May 11, 2020
Continuation 15961331 · Apr 24, 2018
Continuation 15429026 · Feb 9, 2017
Continuation 14736853 · Jun 11, 2015
Continuation 14577705 · Dec 19, 2014
Continuation 14311605 · Jun 23, 2014
Provisional Application 61985946 · Apr 29, 2014
Related Publication 20220079681A1 · Mar 17, 2022
Cited By (17)
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