Cassette system integrated apparatus
A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
1. A pump cassette comprising:
a middle plate interposed between a first plate and a second plate, the middle plate having a first side facing the first plate and a second side facing the second plate;
the first plate comprising a first actuation chamber wall of a first diaphragm valve;
the second plate comprising a second actuation chamber wall of a second diaphragm valve;
the cassette including an actuation chamber port for each of the first diaphragm valve and the second diaphragm valve, each said actuation chamber port extending away from a face of the cassette and configured for connection to separate conduits providing pneumatic pressure to the pump cassette;
wherein the actuation chamber port for the first diaphragm valve connects to a first valve actuation chamber defined by the first diaphragm valve actuation chamber wall and a first valve diaphragm positioned between the first plate and the middle plate; and
wherein the actuation chamber port for the second diaphragm valve connects to a second valve actuation chamber defined by the second diaphragm valve actuation chamber wall and a second valve diaphragm positioned between the second plate and the middle plate.
2. The pump cassette of claim 1 , wherein the first plate comprises a pump actuation chamber wall of a diaphragm pump, the second plate comprises a pumping chamber wall of the diaphragm pump opposite the pump actuation chamber wall of the first plate, and the cassette includes an actuation chamber port for the diaphragm pump, said actuation chamber port extending away from the face of the cassette and configured for connection to a conduit carrying pneumatic pressure to the pump cassette, wherein the actuation chamber port for the diaphragm pump connects to a pump actuation chamber defined by the pump actuation chamber wall and a pump diaphragm positioned between the first plate and the middle plate.
3. The pump cassette of claim 2 , comprising a pumping chamber defined by the pump diaphragm and the pumping chamber wall of the second plate, wherein the pump diaphragm is configured to move from the pump actuation chamber wall of the first plate to the pumping chamber wall of the second plate under positive pneumatic pressure delivered via the pump actuation chamber port to the pump actuation chamber, and wherein the pump diaphragm is configured to move from the pumping chamber wall of the second plate to the pump actuation chamber wall of the first plate under negative pneumatic pressure delivered via the pump actuation chamber port to the pump actuation chamber.
4. The pump cassette of claim 1 , wherein the first diaphragm valve comprises a first valve fluid chamber on the first side of the midplate, the first valve fluid chamber defined by the first valve diaphragm and a first fluid chamber wall on the first side of the midplate, the first fluid chamber wall including two ports connected to a first fluid flowpath on the second side of the middle plate.
5. The pump cassette of claim 4 , wherein the first valve diaphragm is configured to occlude the two ports connected to the first fluid flowpath to interrupt fluid flow in the first fluid flowpath under positive pneumatic pressure delivered to the first valve actuation chamber via the actuation chamber port of the first diaphragm valve.
6. The pump cassette of claim 1 , wherein the second diaphragm valve comprises a valve fluid chamber on the second side of the midplate, the valve fluid chamber defined by the second valve diaphragm and a second fluid chamber wall on the second side of the midplate, the second fluid chamber wall including two ports connected to a second fluid flowpath on the first side of the middle plate.
7. The pump cassette of claim 6 , wherein the second valve diaphragm is configured to occlude the two ports connected to the second fluid flowpath to interrupt fluid flow in the second fluid flowpath under positive pneumatic pressure delivered to the second valve actuation chamber via the actuation chamber port of the second diaphragm valve.
8. A pump cassette comprising:
a middle plate interposed between a first plate and a second plate, the middle plate having a first side facing the first plate and a second side facing the second plate;
the first plate comprising a pump actuation chamber wall of a diaphragm pump, and comprising a first valve actuation chamber wall of a first diaphragm valve;
the second plate comprising a pumping chamber wall of the diaphragm pump opposite the pump actuation chamber wall of the first plate;
the cassette including an actuation chamber port for the diaphragm pump and the first diaphragm valve, each said actuation chamber port extending away from a face of the cassette and configured for connection to separate conduits carrying pneumatic pressure to the pump cassette;
wherein the actuation chamber port for the first diaphragm valve connects to a first valve actuation chamber defined by the first diaphragm valve actuation chamber wall and a first valve diaphragm positioned between the first plate and the middle plate; and
wherein the actuation chamber port for the diaphragm pump connects to a pump actuation chamber defined by the pump actuation chamber wall of the diaphragm pump and a pump diaphragm positioned between the first plate and the middle plate.
9. The pump cassette of claim 8 , wherein the second plate comprises a second actuation chamber wall of a second diaphragm valve, the cassette including a second actuation port for the second diaphragm valve, said second actuation port extending away from the face of the cassette and configured for connection to a separate conduit providing pneumatic pressure to the pump cassette, the second actuation port for the second diaphragm valve connecting to a second valve actuation chamber defined by the second valve actuation chamber wall and a second valve diaphragm positioned between the second plate and the middle plate.
10. The pump cassette of claim 8 , wherein the first diaphragm valve comprises a first valve fluid chamber on the first side of the midplate, the first valve fluid chamber defined by the first valve diaphragm and a first fluid chamber wall on the first side of the midplate, the first fluid chamber wall including two ports connected to a first fluid flowpath on the second side of the middle plate.
11. The pump cassette of claim 10 , wherein the first valve diaphragm is configured to occlude the two ports connected to the first fluid flowpath to interrupt fluid flow in the first fluid flowpath under positive pneumatic pressure delivered to the first valve actuation chamber via the actuation chamber port of the first diaphragm valve.
12. The pump cassette of claim 9 , wherein the second diaphragm valve comprises a valve fluid chamber on the second side of the midplate, the valve fluid chamber defined by the second valve diaphragm and a second fluid chamber wall on the second side of the midplate, the second fluid chamber wall including two ports connected to a second fluid flowpath on the first side of the middle plate.
13. The pump cassette of claim 12 , wherein the second valve diaphragm is configured to occlude the two ports connected to the second fluid flowpath to interrupt fluid flow in the second fluid flowpath under positive pneumatic pressure delivered to the second valve actuation chamber via the actuation chamber port of the second diaphragm valve.
14. The pump cassette of claim 8 , comprising a pumping chamber defined by the pump diaphragm and the pumping chamber wall of the second plate, wherein the pump diaphragm is configured to move from the pump actuation chamber wall of the first plate to the pumping chamber wall of the second plate under positive pneumatic pressure delivered via the pump actuation chamber-port to the pump actuation chamber, and wherein the pump diaphragm is configured to move from the pumping chamber wall of the second plate to the pump actuation chamber wall of the first plate under negative pneumatic pressure delivered via the pump actuation chamber port to the pump actuation chamber.
15. A pump cassette comprising:
a middle plate interposed between a first plate and a second plate, the middle plate having a first side facing the first plate and a second side facing the second plate;
the first plate comprising a first valve actuation chamber wall of a first diaphragm valve, and comprising a pump actuation chamber wall of a diaphragm pump;
the second plate comprising a second valve actuation chamber wall of a second diaphragm valve, and comprising a pumping chamber wall of the diaphragm pump opposite the pump actuation chamber wall of the first plate;
the cassette including an actuation chamber port for each of the diaphragm pump, the first diaphragm valve and the second diaphragm valve, each said actuation chamber port extending away from a face of the cassette and configured for connection to individual conduits carrying pneumatic pressure to the pump cassette;
wherein the actuation chamber port for the first diaphragm valve connects to an actuation chamber defined by the first diaphragm valve actuation chamber wall and a first valve diaphragm positioned between the first plate and the middle plate;
wherein the actuation chamber port for the second diaphragm valves connects to an actuation chamber defined by the second diaphragm valve actuation chamber wall and a second valve diaphragm positioned between the second plate and the middle plate; and
wherein the actuation chamber port for the diaphragm pump connects to a pump actuation chamber defined by the pump actuation chamber wall of the diaphragm pump and a pump diaphragm positioned between the first plate and the middle plate.
16. The pump cassette of claim 15 , wherein the first diaphragm valve comprises a first valve fluid chamber on the first side of the midplate, the first valve fluid chamber defined by the first valve diaphragm and a first fluid chamber wall on the first side of the midplate, the first fluid chamber wall including two ports connected to a first fluid flowpath on the second side of the middle plate.
17. The pump cassette of claim 16 , wherein the first valve diaphragm is configured to occlude the two ports connected to the first fluid flowpath to interrupt fluid flow in the first fluid flowpath under positive pneumatic pressure delivered to the first valve actuation chamber via the actuation chamber port of the first diaphragm valve.
18. The pump cassette of any of claim 15 , wherein the second diaphragm valve comprises a valve fluid chamber on the second side of the midplate, the valve fluid chamber defined by the second valve diaphragm and a second fluid chamber wall on the second side of the midplate, the second fluid chamber wall including two ports connected to a second fluid flowpath on the first side of the middle plate.
19. The pump cassette of claim 18 , wherein the second valve diaphragm is configured to occlude the two ports connected to the second fluid flowpath to interrupt fluid flow in the second fluid flowpath under positive pneumatic pressure delivered to the second valve actuation chamber via the actuation chamber port of the second diaphragm valve.
20. The pump cassette of any of claim 15 , comprising a pumping chamber defined by the pump diaphragm and the pumping chamber wall of the second plate, wherein the pump diaphragm is configured to move from the pump actuation chamber wall of the first plate to the pumping chamber wall of the second plate under positive pneumatic pressure delivered via the pump actuation chamber port to the pump actuation chamber, and wherein the pump diaphragm is configured to move from the pumping chamber wall of the second plate to the pump actuation chamber wall of the first plate under negative pneumatic pressure delivered via the pump actuation chamber port to the pump actuation chamber.